Pharmokinetics and Dynamics

Question 1

Pharmokinetics

Answer 1

Science of the kinetics of drug absorption, distribution, and elimination (metabolism and excretion)

Question 2

Drug disposition

Answer 2

Description of drug absorption, distribution, metabolism + elimination

Question 3

Elimination consists of

Answer 3

Metabolism and excretion

Question 4

Pharmacodynamics

Answer 4

At the side of action

Biochemical and physiologic effects that influence interaction of drugs w/ the receptor

Question 5

PK-PD models

Answer 5

Relate plasma drug levels to drug concentration at site of action + establish intensity + time course of drug

Question 6

Describe Pk_PD models

Answer 6

1. Drug release + dissolution -absorbed
2. Drug in system circulation
   distributed back and forth b/w systemic and tissues
3. From systemic , will be excreted and metabolized through elimination
4. Distributed in drug or tissues to have effect