Pharmakologie HS Flashcards

1
Q

Carbachol

A

direkte Parasympathomimetika (Muskarinrezeptor-Antagonist)

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2
Q

Pilocarpin

A

direkte Parasympathomimetika (Muskarinrezeptor-Antagonist)

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3
Q

Neostigmin

A

indirekte Parasympathomimetika (reversible Cholinersterase-Hemmer)

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4
Q

Pyridostigmin

A

indirekte Parasympathomimetika (reversible Cholinersterase-Hemmer)

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5
Q

Donezepil

A

indirekte Parasympathomimetika (reversible Cholinersterase-Hemmer)

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6
Q

Atropin

A

Parasympatholytika (Muskarinrezeptor-Antagonist)

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7
Q

Ipratropiumbromid

A

Parasympatholytika (Muskarinrezeptor-Antagonist)

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8
Q

Scopolamin

A

Parasympatholytika (Muskarinrezeptor-Antagonist)

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9
Q

Butylscopalamin

A

Parasympatholytika (Muskarinrezeptor-Antagonist)

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10
Q

Biperiden

A

Parasympatholytika (Muskarinrezeptor-Antagonist)

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11
Q

Solifenacin

A

Parasympatholytika (Muskarinrezeptor-Antagonist)

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12
Q

Xylometazolin

A

Adrenozeptor-Agonist (Sympathomimetika) –> alpha-spezifisch

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13
Q

Phenylefrin

A

Adrenozeptor-Agonist (Sympathomimetika) –> alpha-spezifisch

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14
Q

Etilefrin

A

Adrenozeptor-Agonist (Sympathomimetika) –> alpha-spezifisch

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15
Q

Ephedrin

A

Adrenozeptor-Agonist (Sympathomimetika) –> alpha-

+ beta-spezifisch

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16
Q

Noradrenalin

A

Adrenozeptor-Agonist (Sympathomimetika) –> alpha-

+ beta-spezifisch

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17
Q

Adrenalin

A

Adrenozeptor-Agonist (Sympathomimetika) –> alpha-

+ beta-spezifisch

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18
Q

Dopamin

A

Adrenozeptor-Agonist (Sympathomimetika) –> alpha-

+ beta-spezifisch

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19
Q

Isoprenalin

A

Adrenozeptor-Agonist (Sympathomimetika) –> beta-spezifisch

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20
Q

Salbutamol

A

Adrenozeptor-Agonist (Sympathomimetika) –> beta2-spezifisch

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21
Q

Fenoterol

A

Adrenozeptor-Agonist (Sympathomimetika) –> beta2-spezifisch

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22
Q

Amphetamin, Cocain, Ephedrin

A

indirekte Sympathomimetika (viele Sucht- und Dopingmittel) –> mehr NA im synaptischen Spalt

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23
Q

Prazosin

A

Adrenozeptor-Antagonist = Sympatholytika –> alpha1-Blocker

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24
Q

Doxazosin

A

Adrenozeptor-Antagonist = Sympatholytika –> alpha1-Blocker

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25
Q

Propanolol

A

Adrenozeptor-Antagonist = Sympatholytika –> beta-Blocker

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26
Q

Carvedilol

A

Adrenozeptor-Antagonist = Sympatholytika –> beta-Blocker

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27
Q

Metoprolol

A

Adrenozeptor-Antagonist = Sympatholytika –> beta1-Blocker = kardioselektiv

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28
Q

Atenolol

A

Adrenozeptor-Antagonist = Sympatholytika –> beta1-Blocker = kardioselektiv

29
Q

Nebivolol

A

Adrenozeptor-Antagonist = Sympatholytika –> beta1-Blocker = kardioselektiv

30
Q

Clonidin

A

Antisympathotonika –> alpha2-Adrenozeptor-Antagonist

–> Hemmung des Sympathikus + zusätzliche Stimulation des Vagus

31
Q

alpha-Methyldopa

A

Antisympathotonika –> alpha2-Adrenozeptor-Antagonist

–> Hemmung des Sympathikus

32
Q

Nifedipin

A

Ca2+-Kanalblocker

- Dihydropyridin-Typ

33
Q

Amlodipin

A

Ca2+-Kanalblocker

- Dihydropyridin-Typ

34
Q

Verapamil

A

Ca2+-Kanalblocker

- Phenylalkylamin-Typ

35
Q

Diltiazem

A

Ca2+-Kanalblocker

- Benzothiazepin-Typ

36
Q

organische Nitrate

A

NO-Donatoren

37
Q

Molsidomin

A

NO-Donatoren

38
Q

Nicorandil

A

NO-Donatoren

39
Q

Sildenafil

A

PDE-5-Hemmer

–> Viagra

40
Q

Bosentan

A

Endothelin-Rezeptor-Antagonist

41
Q

Macitentan

A

Endothelin-Rezeptor-Antagonist

42
Q

Minoxidil

A

K+ Kanalöffner

43
Q

Diazoxid

A

K+ Kanalöffner

44
Q

Enalapril

A

ACE-Hemmer

45
Q

Captopril

A

ACE-Hemmer

46
Q

Losartan

A

ARB = AT1-Rezeptor-Antagonist

47
Q

Oimesartan

A

ARB = AT1-Rezeptor-Antagonist

48
Q

Aliskiren

A

Renin-Hemmer

49
Q

Chlorthalidon

A

Thiaziddiuretika

50
Q

Hydrochlorothiazid

A

Thiaziddiuretika

51
Q

Furosemid

A

Schleifendiuretika

52
Q

Torasemid

A

Schleifendiuretika

53
Q

Amilorid

A

K+ sparende Diuretika: ENaC-Hemmer

54
Q

Spironolaction

A

K+ sparende Diuretika: Aldosteron-Rezeptor-Antagonist

55
Q

Epleronon

A

K+ sparende Diuretika: Aldosteron-Rezeptor-Antagonist

56
Q

Ivabradin

A

If-Kanalblocker –> Ersatz für beta-Blocker

57
Q

Milrinon

A

PDE-3-Hemmer

58
Q

Amrinon

A

PDE-3-Hemmer

59
Q

Digoxin

A

Digitalisglykoside

60
Q

Digitoxin

A

Digitalisglykoside

61
Q

Chinidin

A

Antiarrhythmika Klasse Ia –> Na+ Kanal-Blocker

62
Q

Prajmalin

A

Antiarrhythmika Klasse Ia –> Na+ Kanal-Blocker

63
Q

Lidocain

A

Antiarrhythmika Klasse Ib –> Na+ Kanal-Blocker

64
Q

Propafenon

A

Antiarrhythmika Klasse Ic –> Na+ Kanal-Blocker

65
Q

Flecainid

A

Antiarrhythmika Klasse Ic –> Na+ Kanal-Blocker

66
Q

Sotalol

A

Antiarrythmika Klasse III –> –> K+ Kanal-Blocker (+ mehr)

67
Q

Amiodaron / Dronedaron

A

Antiarrhytmika Klasse III –> K+ Kanal-Blocker (+ mehr)
–> zusätzlich Blockade von N+ und Ca2+, alpha- und beta-Rezeptoren

Amiodaron = Leitsubstanz der Antiarrhytmika (jedoch viele NW)

68
Q

Adenosin

A

Antiarrhythmika Klasse V –> puringer Agonist

–> negativ chronotrop + dromotrop

69
Q

Mg2+

A

= physiologischer Ca2+ Antagonist

–> Mittel der Wahl bei Torsade-de-Pointes