pharmacy science rap

Question 1

what is a lysome

Answer 1

• acts as a stomach cell
• it is an organelle that engulfs and invades bacteria
• clears damaged cells

Question 2

what is pKa

Answer 2

ph of a solution where the molecule is 50% protonated.

Question 3

how many nucleotides are in 1 colon

Answer 3

3

Question 4

which epithelial cell type are you most likely to find forming the skin.

Answer 4

stratified squamous epithelium

Question 5

muscles

Answer 5

cardiac muscle is both striated and under involuntary control.

Question 6

connective tissue

Answer 6

Macrophages are a class of white blood cells, important for engulfing and breaking down pathogens or damaging substances.

Question 7

in mechanisms of glandular secretion, to produce sweat, which causes the least damage to the glandular cell

Answer 7

merocrine secretion

Question 8

which is the correct order of passage of food through the structures of digestve system

Answer 8

stomach
duodenum
jejunum
ileum
caecum
ascending colon

Question 9

circulatory system

Answer 9

depxygenated blood is carried in the pulmaory arteries to the lungs.

Question 10

anatomical statement

Answer 10

adtenal glands are located directly superior to the kidneys.

Question 11

Which route of administarton will noramlly show the slowest absorption

Answer 11

Oral

Question 12

which route if administartion will potentially result in 1st pass metabolism

Answer 12

Oral

Question 13

which part of the GI tract has a pH of between 6.1 and 7.4

Answer 13

Proximal small intestine

Question 14

which pharmacokinetic term matches the description “the time the plasma conc is above the MEC”

Answer 14

duration of action

Question 15

If a drug had a volume of distribution of 42L where in the body is the drug concentrated

Answer 15

body water

Question 16

after a drug is administrated how long would it atke before you would consider the drug is effectively removed from the systematic circulation

Answer 16

6 half lives

Question 17

when calculating a loading dose, whioch pharmacokinetic paramters is needed

Answer 17

volume of distribution

Question 18

when can non linear pharmacokinetic occur

Answer 18

the metabolism of the drug is saturated at high concentrations

Question 19

A patient has difficulty to swallow tablets, doc advised to crush tablets before swallowing. they have been prescribed enteric coated dosage form. What does it describe

Answer 19

Crushing the tablet would cause it to dissolve in the stomach

Question 20

which quantity changes as a first order reaction proceeds.

Answer 20

rate of reaction

Question 21

Which is not a common packaging item for a cream

Answer 21

blister packs

Question 22

Statement regarding phases of clinical trials and patient numbers

Answer 22

Pre clinical trials examine a drugs efficacy and toxity in a lab setting and phase 3 trials involve the use of placebo.

Question 23

In pahse 1 clinical trial who takes part

Answer 23

volunteers in a certain age range who are in general good health and take part in trials where the dose reponse is measured.

Question 24

who is responsible for releasing the raw material for production

Answer 24

the quality control manager

Question 25

what does the granting of a patent mean for a new potential drug

Answer 25

the intellectual property of the potential drug is protected

Question 26

Statement regarding quality control

Answer 26

the independence of quality control from production is considered fundamental of the satisfactory operation of quality control

Question 27

What is not a benefit of inhaler recycling

Answer 27

Damage to the ozone layer is reduced

Question 28

What is not a route of administration

Answer 28

Dissoloution

Question 29

What is not a typical class of tablet excipent

Answer 29

Suspending agent

Question 30

How are drugs formulated into tablets if they are sensitive to moisture and heat

Answer 30

Direct compression

Question 31

What does API stand for

Answer 31

Active Pharmaceutical ingredient

Question 32

Statement regarding E - factors

Answer 32

It is a measure of the quantity of waste produced for each unit of drug manufactured.