pharmacy science rap Flashcards

1
Q

what is a lysome

A
  • acts as a stomach cell
  • it is an organelle that engulfs and invades bacteria
  • clears damaged cells
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2
Q

what is pKa

A

ph of a solution where the molecule is 50% protonated.

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3
Q

how many nucleotides are in 1 colon

A

3

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4
Q

which epithelial cell type are you most likely to find forming the skin.

A

stratified squamous epithelium

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5
Q

muscles

A

cardiac muscle is both striated and under involuntary control.

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6
Q

connective tissue

A

Macrophages are a class of white blood cells, important for engulfing and breaking down pathogens or damaging substances.

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7
Q

in mechanisms of glandular secretion, to produce sweat, which causes the least damage to the glandular cell

A

merocrine secretion

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8
Q

which is the correct order of passage of food through the structures of digestve system

A

stomach
duodenum
jejunum
ileum
caecum
ascending colon

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9
Q

circulatory system

A

depxygenated blood is carried in the pulmaory arteries to the lungs.

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10
Q

anatomical statement

A

adtenal glands are located directly superior to the kidneys.

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11
Q

Which route of administarton will noramlly show the slowest absorption

A

Oral

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12
Q

which route if administartion will potentially result in 1st pass metabolism

A

Oral

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13
Q

which part of the GI tract has a pH of between 6.1 and 7.4

A

Proximal small intestine

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14
Q

which pharmacokinetic term matches the description “the time the plasma conc is above the MEC”

A

duration of action

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15
Q

If a drug had a volume of distribution of 42L where in the body is the drug concentrated

A

body water

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16
Q

after a drug is administrated how long would it atke before you would consider the drug is effectively removed from the systematic circulation

A

6 half lives

17
Q

when calculating a loading dose, whioch pharmacokinetic paramters is needed

A

volume of distribution

18
Q

when can non linear pharmacokinetic occur

A

the metabolism of the drug is saturated at high concentrations

19
Q

A patient has difficulty to swallow tablets, doc advised to crush tablets before swallowing. they have been prescribed enteric coated dosage form. What does it describe

A

Crushing the tablet would cause it to dissolve in the stomach

20
Q

which quantity changes as a first order reaction proceeds.

A

rate of reaction

21
Q

Which is not a common packaging item for a cream

A

blister packs

22
Q

Statement regarding phases of clinical trials and patient numbers

A

Pre clinical trials examine a drugs efficacy and toxity in a lab setting and phase 3 trials involve the use of placebo.

23
Q

In pahse 1 clinical trial who takes part

A

volunteers in a certain age range who are in general good health and take part in trials where the dose reponse is measured.

24
Q

who is responsible for releasing the raw material for production

A

the quality control manager

25
what does the granting of a patent mean for a new potential drug
the intellectual property of the potential drug is protected
26
Statement regarding quality control
the independence of quality control from production is considered fundamental of the satisfactory operation of quality control
27
What is not a benefit of inhaler recycling
Damage to the ozone layer is reduced
28
What is not a route of administration
Dissoloution
29
What is not a typical class of tablet excipent
Suspending agent
30
How are drugs formulated into tablets if they are sensitive to moisture and heat
Direct compression
31
What does API stand for
Active Pharmaceutical ingredient
32
Statement regarding E - factors
It is a measure of the quantity of waste produced for each unit of drug manufactured.