pharmacy science rap Flashcards
what is a lysome
- acts as a stomach cell
- it is an organelle that engulfs and invades bacteria
- clears damaged cells
what is pKa
ph of a solution where the molecule is 50% protonated.
how many nucleotides are in 1 colon
3
which epithelial cell type are you most likely to find forming the skin.
stratified squamous epithelium
muscles
cardiac muscle is both striated and under involuntary control.
connective tissue
Macrophages are a class of white blood cells, important for engulfing and breaking down pathogens or damaging substances.
in mechanisms of glandular secretion, to produce sweat, which causes the least damage to the glandular cell
merocrine secretion
which is the correct order of passage of food through the structures of digestve system
stomach
duodenum
jejunum
ileum
caecum
ascending colon
circulatory system
depxygenated blood is carried in the pulmaory arteries to the lungs.
anatomical statement
adtenal glands are located directly superior to the kidneys.
Which route of administarton will noramlly show the slowest absorption
Oral
which route if administartion will potentially result in 1st pass metabolism
Oral
which part of the GI tract has a pH of between 6.1 and 7.4
Proximal small intestine
which pharmacokinetic term matches the description “the time the plasma conc is above the MEC”
duration of action
If a drug had a volume of distribution of 42L where in the body is the drug concentrated
body water
after a drug is administrated how long would it atke before you would consider the drug is effectively removed from the systematic circulation
6 half lives
when calculating a loading dose, whioch pharmacokinetic paramters is needed
volume of distribution
when can non linear pharmacokinetic occur
the metabolism of the drug is saturated at high concentrations
A patient has difficulty to swallow tablets, doc advised to crush tablets before swallowing. they have been prescribed enteric coated dosage form. What does it describe
Crushing the tablet would cause it to dissolve in the stomach
which quantity changes as a first order reaction proceeds.
rate of reaction
Which is not a common packaging item for a cream
blister packs
Statement regarding phases of clinical trials and patient numbers
Pre clinical trials examine a drugs efficacy and toxity in a lab setting and phase 3 trials involve the use of placebo.
In pahse 1 clinical trial who takes part
volunteers in a certain age range who are in general good health and take part in trials where the dose reponse is measured.
who is responsible for releasing the raw material for production
the quality control manager
what does the granting of a patent mean for a new potential drug
the intellectual property of the potential drug is protected
Statement regarding quality control
the independence of quality control from production is considered fundamental of the satisfactory operation of quality control
What is not a benefit of inhaler recycling
Damage to the ozone layer is reduced
What is not a route of administration
Dissoloution
What is not a typical class of tablet excipent
Suspending agent
How are drugs formulated into tablets if they are sensitive to moisture and heat
Direct compression
What does API stand for
Active Pharmaceutical ingredient
Statement regarding E - factors
It is a measure of the quantity of waste produced for each unit of drug manufactured.
