Pharmacy Calculations Flashcards
Osmosis
Solvent moves from low conc. to high conc. through semi-permeable membrane until equilibrium reached
Osmotic pressure
Pressure required to stop osmosis (excess pressure applied to solution)
Isosmotic
2 solutions that have same osmotic pressure
Isotonic
Solution that has same osmotic pressure as bodily fluids (e.g. blood, tears) such as IV fluids- no problem
Hypotonic
Solution that has lower conc. of solutes than bodily fluids (e.g. water)- draws fluid out of body
Hypertonic
Solution that has higher conc. solutes than bodily fluids- causes body to swell
Osmoles
Unit measurement that describes no. moles of compound that contributes to osmotic pressure
Osmoles formula
osmol=weight substance (g)/ MW x dissociation factor
Osmolarity
Unit to measure no. particles/ L solution which takes into account any dissociation ionic compounds
Osmolarity formula (Osm/L)
Osmolarity= molarity x dissociation factor
Non-electrolyte
No dissociation- DF=1 (therefore Osmol/L= moles/L)
Electrolyte
DF=no. species (therefore Osmol/L= moles/L x no. species)
Displacement values
Amount of substance (by weight) that will occupy volume 1g Theobroma Oil
Dilution
Decreasing conc. of solute in suitable diluent by increasing amount of diluent
Alligation
Used to calculate no. parts 2 components given strengths same substance (X% and Y%) required to make mixture required to make strength (Z%)