pharmacotherapeutics Flashcards

1
Q

pharm agents used in palliative mgmt of terminal agitation

A

Benzos, antipsychotics, barbituates, ketamine

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2
Q

pharm agents used in palliative mgmt of anxiety

A

Benzos, opioids (to slow respirations for air hunger), antipsychotics for elderly, antihistamines for young.

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3
Q

pharm agents used in palliative mgmt of constipation

A

stimulant laxatives, senna & casanthrol, lactulose/sorbitol/PEG products (osmotic laxatives that draw fluid into the bowels), magnesium citrate, bisacodyl, MOM, cascara, mineral oil

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4
Q

pharm agents used in palliative mgmt of diarrhea

A

anti motility agents

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5
Q

pharm agents used in palliative mgmt of diminished appetite

A

megesterol, dronabinol, corticosteroids, cyproheptadine, antidepressants, androgens-oxandrolone

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6
Q

pharm agents used in palliative mgmt of depression

A

SSRIs, tricyclics, SNRIs, Buproprion

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7
Q

pharm agents used in palliative mgmt of dyspnea/air hunger

A

opiods, benzos, albuterol, ipratropium, furosemide

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8
Q

pharm agents used in palliative mgmt of hiccoughs

A

antipsychotics: chlorpromazine.

Major AE: cardiovascular, CNS (seizures)

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9
Q

pharm agents used in palliative mgmt of nausea/vomitting

A

serotonin receptor antagonist: Ondansetron (AE: HA, constipation); dopamine receptor agonist: prochloroperazine (AE: hypotension)

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10
Q

pharm agents used in palliative mgmt of pruritis

A

antihistamines. AE: drowsiness, allergic rxn

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11
Q

pharm agents used in palliative mgmt of pain

A

somatic: NSAIDS, opioid for mild-mod- severe pain, use WHO ladder. AE: respiratory suppression, constipation.
neuropathic: gabapentin, lidocaine patch, tramadol, tricyclic antidepressants. AE: drowsiness, dizziness, serotonin syndrome, anticholinergic effects

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12
Q

pharm agents used in palliative mgmt of terminal delerium

A

neuroleptics: haloperidol, risperidone
anxiolytics: lorazepam
anesthetics: propofol. AE: hypotension, respiratory depression, dystonia, blurred vision.

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