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Pharmacotherapeutics > Pharmacotherapeutics > Flashcards

Pharmacotherapeutics Flashcards

0
Q

Adalimumab (Humira)

A

Treats plaque psoriasis and psoriatic arthritis

SQ

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1
Q

Etanercept (Enbrel)

A

Treats plaque psoriasis and psoriatic arthritis

SQ

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2
Q

Infliximab (Remicade)

A

Treat plaque psoriasis and psoriatic arthritis

IV

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3
Q

Golimumab (Simponi)

A

arthritis only, not plaque psoriasis

SQ

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4
Q

Ustekinumab (stelara)

A

Interfere with IL-12 and IL-23

SQ

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5
Q

Mycophenolate Mofetil (CellCept)

A

used in combination with other therapies for moderate to severe
oral
category D

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6
Q

Hydroxyurea

A

antimetabolite for hematologic malignancies
psoriasis only
for pt with liver dx who would be at risk of ADRs with other antipsoriatic agents, less effective
Oral

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7
Q

pediatrics

A

0-18 years

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8
Q

premature

A

<37 weeks gestation age

normal is 40 weeks

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9
Q

neonate

A

1 day to 1 month

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10
Q

infant

A

1 month to 1 year

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11
Q

children

A

1-12 years

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12
Q

adolescent

A

12 - 18 years

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13
Q

chloramphenicol

A

gray baby syndrome

could not metabolize drug & accumulated in body & turned grey

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14
Q

thalidomide

accutane

A

phocomelia

flipper like limb syndrome

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15
Q

sulfonamides

A

kernicterus

displace bilirubin and accumulates = jaundice = cross BBB & lodge brain = permanent brain damage.

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16
Q

tablets and capsules for children <6

A

cannot swallow so use liquids, oral disintegrating tables, cheweable tablets

17
Q

subcutaneous in neonates

A

unpredictable, more viable than intramuscular injections, absorption increased in neonates, should inject in abdomen = less risk of injecting into muscle/bone.

18
Q

intramuscular

A

not ideal in neonatal due to absorption issues

19
Q

IV bags for neonates

A

used for maintenance fluids only

20
Q

syringe pump

A

most common technique in pediatrics
allows med to be administered over a set time at specific rate
concentrated solution is slowly dripped into the maintenance fluid for dilute administration

21
Q

volumetric set

A

Buretrol or Metriset
allows for administration of a set volume of medication into a specific volume of diluent to create a patient specific concentration
allows for tubing to the flushed to ensure entire dose is given

22
Q

intraosseous infusion

A

when IV access cannot be gained
should not be used if pt is over 6 years old
can infuse most meds & fluids w exception of lipid based products

23
Q

pediatric chief complaint

A

presented same as in adults but states who is giving the information

24
Q

past medical history

A

adult chart + prenatal & birth history.

NVSD = normal spontaneous vaginal delivery

25
Q

pediatric social history/family history

A

child’s primary living environment, daycare, genetic illnesses in family

26
Q

diet history

A

important for infants

document types of food & amts.

27
Q

pediatric heart rate

A

starts high prior to birth, dips slightly at birth, slowly decreases until age 14 when adult normals are reached

28
Q

pediatric respiratory rate

A

highest at birth, declines until normal adult at 15 years

29
Q

pediatric blood pressure

A

starts low and increases with age.

30
Q

pediatric serum creatinine

A

for the first 10 days of life, the value obtained is indicative of the mother’s renal health, not the child’s renal health
levels are dependent on muscle mass and don’t reach adult normals until adolescence

31
Q

pediatric creatinine clearance

A

maturation occurs btw 6 mo-3 years

32
Q

pediatric bilirubin

A

total bilirubin peaks at 3-7 days of life and decreases as the liver’s ability to conjugate matures. conjugated bilirubin should remain the same throughout a health childhood since body will excrete any excess.

33
Q

pediatric fluids, electrolytes, nutrition (FEN) for non-dehydrated pediatrics patients

A

100 ml/kg for the first 10kg
50 ml/kg for the 2nd 10 kg
20 ml/kg for each extra kg over 20 kg

3 years = D5/.45 NaCl + 20 mEq KCl/L

divide by 24 to get ml/hr rate

34
Q

nelson’s textbook of pediatrics

A

widely available, general reference, req some medical terminology knowledge, a “dipro’s for pediatrics”

35
Q

pediatric dosage handbook by lexicomp

A

excellent drug reference, nothing on diagnosis or treatment plans, FDA information

36
Q

Current Concepts in Pediatric Diagnosis and Therapy

A

UTD std of care, assume you know background on dx staet

37
Q

Harriet Lane Handbook

A

good section on dx & testing, some difficulties w drug section, designed for physicians, questionable drug reference

38
Q

Nelson’s Essentials of Pediatrics

A

handbook on common pediatric dx states

39
Q

Teddy Bear Book

A

peds specific compatibility info of IV for each conc used in children, found very rarely in other resources

40
Q

Neofax

A

limited to medications in neonatal pop

Pharmacotherapeutics (1 decks)

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