Pharmacology YT Flashcards
ASA Ped Dose
324mg PO only if ischemic cardiac hx
Ketamine Adult Dose (induction)
1-2mg/kg SIVP PRN. Maintain with 1/2 induction dose q5-15 mins
Magnesium Sulfate Contraindications (3)
Hypersensitivity, myocardial damage, heart block
Ketorolac Ped Dose
0.5mg/kg (max 30mg) IV
Calcium Gluconate Ped Dose (BB/CCB OD)
20mg/kg IV (max 1g) over 5mins, q5 mins x1 repeat
Nitroglycerine Indications (2)
C/P, APE
Salbutamol Ped Dose (bronchospasm) (2)*
- Ped dosage only applies if weight under 20kg*
- 2.5mg Neb, repeat PRN
- 5x100mcg, repeat PRN
Glucagon Adult Dose (anaphylaxis)
1mg IV, q5 mins max of 5mg total (especially effective for pts on BB/CCB patients)
Ipratropium Bromide Adult Dose (2)
- 500mcg Neb, repeat prn max 1500mcg.
- 3-6 sprays (18mcg/spray) MDI, x1 repeat
Ketamine Ped Dose (induction)
1-2mg/kg SIVP PRN. Maintain with 1/2 induction dose q5-15 mins
Calcium Gluconate Indications (3)
Hypocalcemia, hyperkalemia/crush injury, OD (BB/CCB)
Magnesium Sulfate Adult Dose (torsades)
1-2g IV over 15 mins, q5-15 mins PRN
Salbutamol Adult Dose (hyperkalemia)
20mg Neb
Morphine Adult Dose (2)
- 2-10mg IV/IM, q5-15 mins
- 0.5-4mg/h infusion IV
Midazolam (Versed) Contraindications (3)
Hypersensitivity, narrow-angle glaucoma, myasthenia gravis
Midazolam (Versed) Ped Dose (seizure) (2)
- 0.1mg/kg IV (5mg max), q5 mins PRN
0. 2mg/kg IM/IN (10mg max), q5 mins PRN
Nitroglycerine Adult Dose (C/P) (2)
- 0.4mg SL q5 mins
- 10-20mcg/min IV increase by 5-10mcg/min every 5-10 mins PRN
Magnesium Sulfate Adult Dose (asthma)
2g IV over 10 mins
Fentanyl Adult Dose (for pain)
25-50mcg IV, q5-15 mins PRN
Midazolam (Versed) Adult Dose (intubation)
0.1mg/kg IV
Fentanyl Contraindications (1)
Hypersensitivity to opiates
Glucagon Adult Dose (BB/CCB OD)
5mg IV, q10 mins x2 repeats
Haloperidol Contraindications (4)
Hypersensitivity, Parkinson’s, CNS depression, 1/2 doses or alternate medication for hypotension
Magnesium Sulfate Indications (4)
Torsades, eclamptic seizure, TCA OD, asthma
Glucagon Ped Dose (hypoglycemia)*
- Ped dosage only applies if weight is less than 25kg*
0. 5mg IM
Haloperidol Adult Dose
2.5-10mg IM, q5-10 mins max 100mg
Calcium Gluconate Ped Dose (hyperkalemia/crush injury)
20mg/kg IV (max 1g), q5 mins x1 repeat
Glucagon Contraindications (2)
Hypersensitivity, pheochromocytoma
Ephedrine Indications (1)
Post-intubation hypotension (persistant)
Ondansetron Ped Dose
0.1mg/kg IM/IV, max 4mg
Morphine Contraindications (2)
Hypersensitivity, MAOI use in last 14 days
Ipratropium Bromide Ped dose (2)*
- Ped dosage applies only if weight less than 30kg*
- 250mcg Neb, q15mins x2 repeats.
- 4 sprays (18mcg/spray) MDI, q15mis x2 repeats
Adenosine Ped Dose
0.1mg/kg RIVP (max 6mg), q1-2 mins x1 repeat of 0.2mg/kg (max 12mg)
Salbutamol Indications (2)
Bronchospasm, hyperkalemia
Magnesium Sulfate Adult Dose (TCA OD)
1-2g IV over 5 mins
Magnesium Sulfate Adult Dose (eclamptic seizure)
4g in 100cc IV over 15 mins
Ketamine Indications (3)
Induction, pain, combative
Glucagon Adult Dose (hypoglycemia)
1mg IM
Ephedrine Adult Dose
0.2mg/kg IV (max 10mg), q5 mins PRN
Ketamine Contraindications (4)
Hypersensitivity, HTN/CHF, high ICP, thyrotoxicosis (increased thyroid hormone causing psychosis)
Ketorolac Contraindications (2)
Bleeds, advanced renal/hepatic impairment
Ketamine Adult Dose (combative)
1mg/kg SIVP PRN
4-5mg/kg IM
Infuse at 1-2mg/kg/h
Haloperidol Indications (1)
Chemical restraint
Nitroglycerine Contraindications (5)
Hypersensitivity, BP less than 100, ED drugs last 2/48h, severe anemia, cardiac tamponade/restrictive pericarditis
Fentanyl Indications (2)
Severe pain, adjunct for intubation
Ketamine Adult Dose (pain)
0.25-0.5mg/kg SIVP, q3-5mins max 35mg
Fentanyl Adult Dose (for intubation)
1-3mcg/kg IV. Maintain with 50-200mcg/h
Succinylcholine Adult Dose
1.5mg/kg IV, maintain with Rocuronium or analgesic maintenance
Calcium Gluconate Adult Dose (hypocalcemia)
7-14mEq IV over 15-30 mins
Magnesium Sulfate Ped Dose (asthma)
50mg/kg (max 2g) IV over 20 mins
Calcium Gluconate Contraindications (3)
Known hypercalcemia, VF, digoxin toxicity (as it may delay depolarization causing VF/VT)
Succinylcholine Ped Dose
2mg/kg IV, maintain with Rocuronium or analgesic maintenance
Nitroglycerine Adult Dose (APE)
0.4mg SL (or 0.8mg if BP over 160mmHg systolic), then maintain with 20mcg/kg IV, titrate to effect
Morphine Ped Dose (2)
- 0.1mg/kg IV/IM (max 5mg) q5-15 mins
- 0.02-0.06mg/kg/h infusion IV
Ketorolac Adult Dose
15-30mg IM/IV, q6h max 120mg/day
Glucagon Indications (3)
Hypoglycemia, BB/CCB OD, anaphylaxis refractory to fluids/epinephrine
ASA Contraindications (4)
Hypersensitivity, ongoing bleed, peds with viral symptoms, asthma with hx of ASA causing exacerbation
Adenosine Adult Dose
6mg RIVP, q1-2 mins x1 repeat of 12mg
Ipratropium Bromide Contraindications (2)
Hypersensitivity, Allergy to peanuts/soy
Fentanyl Ped Dose (for pain)
0.5mcg/kg IV (max 50mcg), q5-15 mins PRN
Salbutamol Adult Dose (bronchospasm) (2)
- 5mg Neb, repeat PRN
- 8x100mcg MDI, repeat PRN
Midazolam (Versed) Ped Dose (intubation)
0.1mg/kg IV
Glucagon Ped Dose (BB/CCB OD)
0.1mg/kg IV (max 5mg), q5 mins total max 10mg
Calcium Gluconate Adult Dose (BB/CCB OD)
1g IV over 5 mins, q10-15 mins x2 repeat
Fentanyl Ped Dose (for intubation)
0.5-1mcg/kg IV. Maintain with 0.5-5mcg/kg/h
Midazolam (Versed) Adult Dose (seizure) (2)
- 5mg IV q5-10 mins PRN
- 10mg IM/IN q5-10 mins PRN
Midazolam (Versed) Adult Dose (violent)
2-5mg IM/IN, repeat PRN max 10mg
Ketamine Ped Dose (pain)
0.3mg/kg SIVP
Ephedrine Contraindications (1)
Hypersensitivity to sympathomimetics
Ephedrine Ped Dose
Epinephrine preferred for pediatrics
Midazolam (Versed) Ped Dose (violent)
0.2mg/kg IM/IN, repeat PRN max 8mg
ASA Adult Dose
324mg PO
Succinylcholine Contraindications (4)
Hypersensitivity, hyperkalemia, hx of malignant hyperthermia, major burns/trauma in last 24h
Salbutamol Contraindications (2)
Hypersensitivity, hemodynamically significant tachyarrythmias
Salbutamol Ped Dose (hyperkalemia)
2.5-5mg Neb continuous
Ondansetron Contraindications (3)
Hypersensitivity, current apomorphine use, congenital long QT syndrome
Midazolam (Versed) Indications (3)
Seizure, violent, adjunct for intubation
Adenosine Contraindications (4)
Hypersensitivity, poison/drug-induced tachycardia, 2nd/3rd-degree heart block, A-fib/sick sinus syndrome with rate above 220
Ondansetron Adult Dose
4-8mg IV/IM, max 8mg
Haloperidol Ped Dose
0.05-0.15mg/kg IM/IV (max 2mg IV and 5mg IM), q1h PRN
Calcium Gluconate Adult Dose (hyperkalemia/crush injury)
1g IV over 5mins, q20 mins x1 repeat
Amiodarone Adult Dose (refractory VF/VT)
300mg IV, q3-5 mins x1 repeat of 150mg
Amiodarone Ped Dose (refractory VF/VT)
5mg/kg IV (max 300mg), q5 mins x 2 repeats
Amiodarone Adult Dose (VT with pulse)
150mg IV over 10 mins
Amiodarone Ped Dose (VT with pulse)
5mg/kg IV (max 300mg) over 20-60 mins
Amiodarone Contraindications (4)
Hypersensitivity, 2nd/3rd-degree heart block, prolonged QT, pre-excitation a-fib
Acetaminophen Indications (2)
Mild to moderate pain, Fever (38.5 degrees+)
Acetaminophen Adult Dose
500-1000mg PO/PR
Acetaminophen Ped Dose
10-15mg/kg PO/PR (max 1000mg)
Acetaminophen Contraindications (2)
Hypersensitivity, hepatic failure
Norepinephrine Adult Dose
0.1-1mcg/kg/min IV, titrate to effect
Norepinephrine Ped Dose
0.05-0.1mcg/kg/min IV titrate by 0.02mcg/kg/min PRN (max 2mcg/kg/min)
Norepinephrine Contraindications (2)
Hypersensitivity, hypovolemia
Pantoprazole Indications (2)
GERD/ulcers, GI bleed
Pantoprazole Adult Dose (GERD/ulcers)
40mg IV/PO
Pantoprazole Adult Dose (GI bleed)
80mg IV over 15 mins, then an additional 40mg @8mg/h
Pantoprazole Contraindications (2)
Hypersensitivity, lactation
Atropine Indications (2)
Symptomatic bradycardia, organophosphate poisoning
Atropine Adult Dose (bradycardia)
0.5mg IV, q3-5 mins max 3mg
Atropine Ped Dose (bradycardia)
0.02mg/kg IV (min of 0.1mg, max of 0.5mg), q3 mins x1 repeat
Atropine Adult Dose (organophosphate poisoning)
2-5mg IV, q2-5 mins PRN
Atropine Ped Dose (organophosphate poisoning)
0.05mg/kg IV (min 0.1mg, max 5mg), q2-5mins PRN
Atropine Contraindications (2)
Hypersensitivity to anticholinergics, tachycardia
Diphenhydramine Adult Dose
50mg IV/IM/PO
Diphenhydramine Ped Dose
1mg/kg IM/IV/PO (max 40mg)
Diphenhydramine Contraindications (1)
Hypersensitivity
Dopamine Adult Dose
Renal: 0.5-2mcg/kg/min IV
Beta 1: 2-10mcg/kg/min IV
Alpha: 10-20mcg/kg/min IV
Dopamine Ped Dose
Increase the following by 1mcg/kg/min:
Renal: 0.5-2mcg/kg/min IV
Beta 1: 2-10mcg/kg/min IV
Alpha: 10-20mcg/kg/min IV
Dopamine Contraindications (1)
Hypersensitivity
Dimenhydrinate Adult Dose
25-50mg IM/IV (12.5mg if frail or elderly)
Dimenhydrinate Ped Dose
1.25mg/kg SIVP (max 40mg)
Dimenhydrinate Contraindications (1)
Hypersensitivity to Gravol, Benedryl, or caffeine
Thiamine Indications (2)
Hypoglycemia with ETOH abuse/malnourishment, methanol ingestion
Thiamine Adult dose (hypoglycemia)
100mg IV/IM
Thiamine Adult dose (methanol ingestion)
100mg IV/IM
Thiamine Contraindications (1)
Hypersensitivity
Oxytocin Adult Dose
10 units IM, then maintain with: 40 units in 1000mL, bolus 500mL then 125mL/h infusion
Oxytocin Contraindications (1)
Pt candidate for multiple births
TXA Adult Dose
1g IV over 10 mins
TXA Ped Dose
15mg/kg IV (max 1g) over 10 mins
TXA Contraindications (3)
Hypersensitivity, over 3h past injury, ongoing thromboembolism
Sodium Bicarbonate Indications (4)
Acidosis, OD (sympathomimetic, BB, TCA, ASA, methanol), anticholinergic poisoning, crush syndrome/hyperkalemia
Sodium Bicarbonate Adult Dose (acidosis)
2-5 mEq/kg IV over 4-8 hours
Sodium Bicarbonate Ped Dose (acidosis)
1 mEq/kg IV (max 50 mEq)
Sodium Bicarbonate Adult Dose (OD)
1-2 mEq/kg IV, if no response infuse 150 mEq in 1000mL @ 250mL/h IV
Sodium Bicarbonate Ped Dose (OD)
1-2 mEq/kg IV, if no response infuse 150 mEq in 1000mL @ 250mL/h IV
Sodium Bicarbonate Adult Dose (anticholinergic poisoning)
1 mEq/kg SIVP, q5 mins x1 repeat, if no response: infuse 150 mEq in 1000mL @ 250mL/h IV
Sodium Bicarbonate Adult Dose (crush/hyperkalemia)
50 mEq IV
Sodium Bicarbonate Ped Dose (crush/hyperkalemia)
1 mEq/kg SIVP (max 50 mEq)
Sodium Bicarbonate Contraindications (2)
Early cardiac arrest, early respiratory arrest
Dextrose Adult Dose
10-25g IV, repeat PRN
Dextrose Ped Dose
0.5g/kg IV (max 25g), repeat PRN
Dextrose Ped Younger Than 6w Dose
0.2g/kg IV (max 25g), repeat PRN
Furosemide Indications (2)
APE, hyperkalemia with ECG changes
Furosemide Adult Dose (APE)
40-80mg IV (consider larger dose if they take large dose furosemide)
Furosemide Adult Dose (hyperkalemia with ECG changes)
20-40mg IV
Furosemide Ped Dose (hyperkalemia with ECG changes)
0.5-1mg/kg IV (max 40mg)
Furosemide Contraindications (3)
Hypersensitivity, anuria, severe hypotension
Diazepam (Valium) Adult Dose
5mg IV, q5-10mins PRN
Diazepam (Valium) Ped Dose
0.3mg/kg IV (max 5mg), q5-10 mins PRN
Diazepam (Valium) Contraindications (2)
Hypersensitivity, hypoglycemic seizures
Lorazepam (Ativan) Indications (3)
Seizure, violent, anxiety
Lorazepam (Ativan) Adult Dose (seizure)
2mg IV, q5 mins PRN
Lorazepam (Ativan) Ped Dose (seizure)
0.1mg/kg SIVP (max 4mg), q5 mins x1 repeat
Lorazepam (Ativan) Adult Dose (violent)
2-4mg IV/IM/PO, q10 mins until sedation
Lorazepam (Ativan) Ped Dose (violent)
0.1mg/kg IV (max 4mg), q5 mins 1/2 doses PRN
Lorazepam (Ativan) Adult Dose (anxiety)
1-2mg IV/PO, q10 mins max 8mg
Lorazepam (Ativan) Contraindications (3)
Hypersensitivity, narrow-angle glaucoma, myasthenia gravis
Epinephrine Indications (4)
Severe bronchospasm, anaphylaxis, cardiac arrest, croup
Epinephrine Adult Dose (bronchospasm)
0.3mg IM, q5-10 mins x2 repeats
Epinephrine Ped Dose (bronchospasm)
0.01mg/kg IM (max 0.3mg), q5-10 mins x 2 repeats
Epinephrine Adult Dose (anaphylaxis)
0.3mg IM, q5 mins PRN
Epinephrine Ped Dose (anaphylaxis)
0.01mg/kg IM (max 0.3mg), q5 mins PRN
Epinephrine Adult Dose (cardiac arrest)
1mg IV (1:10’000), q3-5 mins PRN
Epinephrine Ped Dose (cardiac arrest)
0.01mg/kg IV (1:10’000) (max 1mg), q3-5 mins PRN
Epinephrine Ped Dose (croup)
0.5mg/kg Neb (max 5mg), mixed with 5mL of NS