Pharmacology & Toxiology -Dr An Flashcards
1
Q
Bioavailability
A
Amount of drug reaching plasma unchanged
2
Q
Drug absorption
Factors affecting absorption
A
- concentration gradient
- thickness of the membrane
- surface area
- time in contact
- permeability of the membrane
3
Q
Drug absorption-Mechanism
A
- simple diffusion
- facilitated diffusion ( carrier mediated)
- active transport ( carrier mediated)
- filtration via membrane pores
- bulk flow( intercellular pores and capillaries)
- endocytosis
