Pharmacology TCM Flashcards
Barium Enema
polyps, diverticulosis, motility of colon or rectum
- colon cancer (ascending colon), UC (descending), Crohns (esophagus to lower colon- primarily left), Dx blood in stools, diarrhea, constipation
Barium Swallow
upper GI- ulcers (ST/esophageal), polyps, diverticulosis, motility and peristalsis of the esophagus. ST, duodenum, SI
- narrowing or irritations of esophagus, dysphagia, ulcers, tumors, polyps in upper GI, GERD
CT scan
Tumors, blood clots, biliary obstruction, aneurysms
- Great for post trauma injuries such as MVA
- Better for acute sx (chest, abdominal, lung)
- best at identifying cancer such as lymphoma
- very good for diagnosis spinal problems, injuries to hands, feet, blood vessels, muscles. , blood clots, internal bleeding, tumors
MRI
atherosclerotic tissue, joints, spine, brain, valves of the heart, tendons and ligaments when patient is stationary* - end result testing
- frequently used for: aneurysms, MS, Spinal Cord injuries, Stroke, arthritis, Tumors
KUB (Kidney Ureter Bladder)
size, shape, position of urinary organ, kidney stones
Ultrasound-
gallbladder, kidneys, pancreas, bladder, arterial blood, liver and reproductive organs
Arthrography
joint, tendon, cartilage and ligament condition while patient moves (*MRI is used for sedentary views)
SPECT
extent of brain damage post stroke
PET
diagnosing parkinson’s epilepsy, mental illness as well as metabolic activity to organs
Laproscopy
fiber optic tube used to view contents w/in abdomen & pelvis
What is the best radiography exam to diagnose an AAA (abdominal aortic aneurysm)
CT Scan
X Ray
arthritis, bone cancer, breast tumors, digestive problems, enlarged heart, fractures, osteoporosis, swallowed items, tooth decay (gut healthy)
Pharmacology
characteristic of a natural drug and their sources
pharmacodynamics
study of what drugs do to the body
pharmacokinetics
study of what the body does to a drug
pharmacotherapeutics
how drugs are used to treat disease
toxicology
poisons or poisonous effects of drugs
Absorption-
converting a drug into something the body can use
distribution
process of transporting a drug from its given site to its action site
metabolism
transformation process of a drug into metabolites (age, immunity can interfere with metabolism of drugs
Excretion
how medication is eliminated (feces, urine)
Pregnancy Categories (used to rank birth defects or termination of the fetus) A B C D E NR
A- No Risk B- no risk in humans *C- indeterminate risk, benefits outweigh risks (could be cardiac medication or nausea - pregnancy) D- high risk E- contraindicated NR- no rating
Controlled Substance Schedule (used to identify risk of abuse. Primarily opiates are monitored) I II III IV V
() trade name
generic no bracket
SCHEDULE I- high abuse, no medical use in US; can’t be prescribed. Ex: Heroin, LSD, MDMA, marijuana
SCHEDULE II- HIGH abuse and dependency (still considered for therapeutic use)
Narcotics: morphine, oxycodone, opium, codeine, methadone, dilaudid, demoral, Percocet
Stimulants: amphetamine (Dexedrine, adrenal, methamphatmine (desoxyn), methylphenidate (Ritalin) cocaine
SCHEDULE III- low abuse may cause dependence (steroids, analgesics, barbiturates, anti-diarrheal- most common)- less than 15mg of hydrocodone or 90mg of codeine
SCHEDULE IV- low abuse, limited dependence, used recreationally (benzos; Valium (diazepam), calium, lorazepam (Ativan), xanax, clonazepam/klonopin, (soma) - these can reduce the efficiency of acupuncture
SCHEDULE V- LOW abuse, limited dependence (antitussive, anti-diarrheal, cough medicine)
If a patient is on 110mg of codeine what schedule of drug are they in?
Schedule II
Methods of Administration: Buccal
Water absorbed- Used for people with liver or stomach absorption issues.
Cardiuvascular drugs, steroids, barbiturates, enzymes, vitamins
Methods of Administration: Sublingual
under the tongue, fast absorption like buccal with many of the same meds
Methods of Administration: Transdermal
absorbed through the skin (steroids, hormones, opioids) for slow drug release
- don’t touch someone else’s transdermal patch
Methods of Administration: Intradermal
creates a wheal, makes a bubble under the epidermis and slowly absorbs into the dermis. Ex. allergy testing
Methods of Administration: Subcutaneous
administered as a bolus into the layer of skin below the dermis and adipose
*Morphine, insulin
Methods of Administration: Intramuscular
acts as a depot for the medication which slowly releases into the blood stream
- thorazine, methotrexate, morphine, codeine
Peak serum concentration 30min- 3 hours (for absorption)
Methods of Administration: Intravenous
fastest absorption as it enters the blood stream; risk for overdose or marked interactions. End of infusion (immediate) (usually and IV bag)
**Penicillin peak serum concentration administration
peak serum concentration is 4-24 hours all routes
- If patient it taking probiotic you have to wait 24 hours after probiotic dosage to prescribe penicillin otherwise it will counteract.
Methods of Administration: Oral
taken via mouth- most common however, it has been linked with higher liver, stomach pathology.
Peak serum concentration 30min-6 hours
Methods of Administration: vaginal
douches, suppositories, antifungals, antivirus, in vitro fertilization
Methods of Administration: rectal
Rectal: suppositories, enemas
Suffixes: -amil
calcium channel blockers
Suffixes: -caine
local anethetics
- lidocaine
Suffixes: -dine
H2 blockers, anti ulcer agents
- rantadine
Suffixes: -done
opoids- mathadone
Suffixes: -ide
oral hypoglycemic
- glipizide, glimepiride (oral hyperglycemic),
Suffixes: -lam
anti anxiety
- alprazolam
Suffixes: mycin
antibiotic
-erythromycin, azythromycin
Suffixes: -mide
diuretic
- furosimide (contraindicated with Fu Ling)
Suffixes: nuim
neurological blocker
Suffixes: - olol
betablocker
- troprol-XL
Suffixes: - pam
antianxiety
- diazepam (valium), lorazepam (Ativan)
Suffixes: - pine
calcium channel blockers
Suffixes: - pril
ACE inhibitors, enalapril, ramipril
- progressive cough
Suffixes: -sone
Steriods
cortisone, hydrocortisone
Suffixes: -statin
Antihypertensives
- Shan Zha (hawthorne) - agonist with statins
Suffixes: -vir
Vir = viral, Antiviral
aciclovir (acyclovir) - think herpes
Suffixes: -zide
diuretics
- dyazide (potassium sparing)
Analgesic
mild to severe pain reliever
*Anticholinergic
Blocks parasympathetic nerve impulses, motion sickness
spasm of muscles in GI, COPD, parkingson’s,
meds: flexural, phenergen
side effects: dry mouth (decreased saliva = increased cavities), blurred vision, constipation, sedation, hallucinations,
*Antacid
neutralizes stomach acid
*Anti depressent (tricyclic, MAOI, SSRI, SNRI)
read more in course notes
relieves depression
Selctive Serotonin reuptake Inhibitors = SSRIs
Serotonin and Norepinephrine Reuptake = SNRIs
Monoamine Oxidase Inhibitors = MAOIs (last resort med ***and do not eat tyramine rich foods)
Meds: prozac, Paxil, Zoloft, celexa, lexapro, trazodone, Wellbutrin
*Anticonvulsant
prevents, controls, or relieves seizures
**Anti-diabetic (read more in course notes)
Treats diabetes - rapid acting insulin, peak in 1-3 hours
Meds: lispro (Humalog), (Novolog)
**Metformin = migraine, joint pain, dry mouth, Spontaneous pneumothorax (do not needle upper thorax or chest points)
anti inflammatory (NSAIDS, Steroids)
reduces inflammation
Antihistamine
counteracts histamine, relieves allergies
- often patients forget to tell you they take these
- acupuncture requires a histamine effect- thus antihistamines will inhibit the tx
Anthelmintic
kills parasites and their eggs
Antineoplastic
destroys cancer cells
cathartic
alleviates constipation - Da Huang
a patient presents to you with elevated blood glucose, hypertension, hypercholesterolemia and weight gain- what is the most likely diagnosis
metabolic syndrome
What is not a symptoms of Type 2 diabetes: A) paresthesia B) lack of appetite C) increased thirst D) increased urination
B) lack of appetite
Which is not a s/s of hypoglycemia? A) blurred vision B) weakness C) dry and flushed skin D) headache
C) dry and flushed skin
Which of the following statements about portal hypertension is not true?
A) it can be caused by cirrhosis of the liver
B) it can lead to ascites
C) it can cause caput medusae or purple veins that can be seen around the umbilicus
D) it is due to an increase in pressure in hepatic portal artery
D
which type of anemia is caused by lack of intrinsic factor and inability to absorb B12
pernicious anemia
stool which is black and tarry/sticky when passed most likely indicates
upper gastrointestinal bleed
all of the following statements about Crohn’s disease are correct except:
A) it affects only partial thickness of bowel tissue
B) it can produce cramping and severe abdominal pain
C) it may cause significant weight loss
D) it can cause fistulae and abscesses
A) it affects only partial thickness of bowel tissue
a patient presents with severe RLQ pain, N/V, and fever of 101. Bowel sounds are evident in all four quadrants. Her WBC count is elevated and she tests positive when you perform McBurney’s test. Your patient’s most likely diagnosis is:
Appendicitis
severe epigastric pain that radiates to the right shoulder. she is concerned that it may be a side effect from the lipitor that her MD prescribed. It seems to come and go and is worse when she eats fatty foods. whats her diagnosis?
Cholelithiasis
lack of which vitamin is associated with pernicious anemia
B12
pain just below the right costal margin at the midclavicular line with deep inhale and pressure placed on that spot could be…
cholecystitis
what is the expected incubation period of Hep B
50-180 days
What is transmitted through fecal-oral route?
Hep A & E
47 year old with acute lower GI bleed; knowing that the most common cause of acute lower GI bleed in patients above 40 is (blank), you would refer out for what test?
Diverticulosis
78
which of the following conditions can be characterized by right lower quadrant abdominal pain, fever, nausea, vomiting, constipation, and increase in WBC count
appendicitis
79
45 year old male comes into your clinic w/ RUQ pain, nausea that comes and goes, and a strange tenderness in his costovertebral region. which condition does this present as?
cholecystitis
80
what does the HbA1C level have to be to be rendered Diabetic?
6.5% or over
which of the following is a first-line medication for treatment of Type 2 diabetes
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Metformin
82 a 39 year old patient develops GERD over the course of 6 years in a high stress job. He is asking for a dietary plan from you. Your recommendation to him should be to avoid all of the following except: A) caffeine B) alcohol C) H2 receptor antagonist D) nicotine
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H2 Receptor antagonist
83
abdominal pain that worsens with consumption of food.. what is the likely diagnosis?
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gastric ulcer
84
abdominal discomfort in which the pt feels incomplete relief w/ defecation and intermittent diarrhea interrupted by constipation. Aggravated by psychological factors?
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IBS
86 Colonoscopy is used to visualize A) LI & SI B) LI C) Esophagus, ST, Duodenum D) LI, SI, ST
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LI
87
which of the following regions of the GI tract are sites of enzyme release for carbohydrate digestion?
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Mouth and Small intestine
88
Which of the following regions of the GI tract is the site of enzyme release for Fat digestion?
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Small Intestine
89
the small intestine region of the GI tract consists of ?
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Duodenum, Jejunum, Ileum
90
which of the following conditions presents pathology above pectinate line and is not painful
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internal hemorrhoid?
91
which pathogen is the major cause of acute diarrhea in US during winter months (is found at high rates in day care centers and kindergartens)
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Rotavirus
92
which of the following viruses can spread quickly in closed places such as day care centers, nursing homes, schools and cruise ships?
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Norovirus
93
Upper GI and Lower GI is divided by which anatomical sites?
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ligament of treitz
94
internal hemorrhoids are…
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above the pectinate line, non-painful
95
patient enters with diarrhea and a history of recent antibiotic use.. which is most likely the cause?
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Clostridium difficile
96
Vaccines are available for which of the following varieties of Hepatitis?
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Hep A & B
97
Which forms of hepatitis have abrupt onset?
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Hep A & E