pharmacology quiz

Question 1

This is the study of drugs and their interactions with the living system?

Answer 1

Pharmacology

Question 2

Non-Proprietary name of a drug that reflects important pharmacologic characteristics of the drug?

Answer 2

Generic name

Question 3

This is the name of a drug, given by the manufacturer, for example, Panadol?

Answer 3

Trade

Question 4

This is a form of drug preparation that contains the active and ‘filler’ ingredients. it can come in different colours and shapes?

Answer 4

Tablet

Question 5

A device that contains the active ingredient of the drug is a formulated as an inhaler?

Answer 5

Puffer

Question 6

A Form of drugs with active ingredient dissolved in sweetened liquid formulated for young children?

Answer 6

Syrup

Question 7

This form of drug preparation contains the active ingredient within a solid base of glycerine, to be inserted into the rectum?

Answer 7

Suppository

Question 8

This form of drug preparation has a 2-piece hard shell that encases the active ingredient?

Answer 8

Capsule

Question 9

A route of drug administration that can be administed through a central or peripheral vein

Answer 9

Intravenous

Question 10

A form of drug preparation that contains undissolved particles, Important to shake before use?

Answer 10

Suspension

Question 11

The is the study of how drugs move through the body?

Answer 11

Pharmacokinetics

Question 12

Movement of drugs from the site of administration into the bloodstream?

Answer 12

Absorption

Question 13

Movement of drug from the bloodstream, into cells?

Answer 13

Distribution

Question 14

Alteration of drug and structure, mediated by enzymes?

Answer 14

Metabolism

Question 15

Movement of drug and metabolites out of the body.Main body organ in this process, the kidneys?

Answer 15

Excretion

Question 16

Drugs that increase (activate) one of the P450 enzymes in the liver as known as?

Answer 16

inducers

Question 17

Drugs that decrease (slow) the rate of drug metabolism by one of the P450 enzymes in the liver are called?

Answer 17

inhibitors

Question 18

Drugs administered in an inactive form which need to be activated by the liver?

Answer 18

Prodrug

Question 19

if a drug undergoes extensive hepatic inactivation because of first-pass metabolism, this drug has low?

Answer 19

Bioavailability

Question 20

This is the time taken for the concentration of the drug in the blood to fall by half its original value?

Answer 20

Half-life

Question 21

pick the correct answer to these questions?

1.——— Factor that decreases renal drug excretion due to ageing process ?

2.________ Factor that can be used to increase aspirin excretion ?

3.________ Factor that needs to be considered in drug dosing to avoid toxicity?

4. __________ Factor that need to be considered when prescribing and administering multiple medications to the same patient?

Competitive tubular transport
pH-dependent ionisation
people 80 years and older
Decreased rental function

Answer 21

1. people 80 years and older
2. pH- dependent ionisation
3. Decreased renal function
4. Competitive tubular transport

Question 22

Prodrugs are medications that must be administered intravenously to bypass liver metabolism ? (True or false )

Answer 22

False

Question 23

Grapefruit juice is widely recognised to decrease the rate of drug metabolism and thus, can increase drug levels? (True or False)

Answer 23

True

Question 24

which is the answer of these questions ?

1. _______ Factor that promotes lipid-soluble drugs to readily enter cells?
   2._______ Factor that may be limit drug distribution due to abscesses or tumours?
2. ________ Factor that could slow the amount of free drugs in the bloodstream?
3. ________ Factor that prevents drugs from entering the central nervous system ?

Answer 24

1. Lipid-soluble drugs
2. Blood flow to tissues
3. Affinity to serum proteins
4. Blood- brain barrier

Question 25

which of the following drug forms is intended for systemic therapeutic effect? Irrigation fluid Transdermal patch Eye drops or ointment Ear drops or ointment Vaginal pessaries

Answer 25

Transdermal patch

Question 26

Which of the following are classified as parenteral route of drug administration? Intravenous Intramuscular Oral Rectal Subcutaneous

Answer 26

Intravenous Intramuscular Subcutaneous

Question 27

Properties of an ideal drug are the following ( select all the apply) which of these answers are the correct one ? It has a multiple therapeutic actions It is effective It is safe It only produces the intended therapeutic effects

Answer 27

It only produces the intended therapeutic effects

Question 28

which one of these are the correct answer of these question 1. ________ is the movement of drug and metabolites out of the body ? 2. _________ is the movement of drug from the bloodstream into cells? 3. __________ is the movement of drug from site of administration into the bloodstream? 4. ________ is the alteration of drug structure, mediated by enzymes.? Biotransformation Distribution Excretion Absorption

Answer 28

1. Excretion 2. Distribution 3. Absorption 4. Biotransformation

Question 29

There can be a number of trade name or brand names for the same drug that are sold in Australia? (True or false)

Answer 29

True

Question 30

Drugs, prepared for oral administration, can be crushed, prepared using aseptic technique, and administered through intravenous route? (True or false)

Answer 30

False

Question 31

Sterile water for irrigation is the same as sterile water for injection ? ( True or False)

Answer 31

False

Question 32

Which of the following properties of a drug that would promote rapid absorption? Lipid-soluble water-soluble gas-soluble sustained-release enteric-coated

Answer 32

Lipid-soluble

Question 33

Injecting drugs into the marrow of a bone is an emergency is known as ? Intramuscular administration endotracheal administration intravenous administration intraosseous administration subcutaneous administration

Answer 33

intraosseous administration

Question 34

First-pass effect (first-pass metabolism) refers to: which one is the correct answer? renal inactivation of drugs administered via the oral route renal inactivation of drugs administered via the subcutaneous route hepatic inactivation of drugs administered via the subcutaneous route hepatic inactivation of drugs administered via the intramuscular route hepatic inactivation of drugs administered via the oral route

Answer 34

hepatic inactivation of drugs administered via the oral route

Question 35

Drug-drug interactions can either increase or decrease the rate of drug metabolism? (True or false )

Answer 35

True

Question 36

Nebulised medication are administered through the? skin joint peritoneum ear nose

Answer 36

Nose

Question 37

Which of the following injectable drugs can be administered via the endotracheal tube? ( Select all apply) naloxone fentanyl ( Duragesic) sodium bicarbonate atropine morphine

Answer 37

naloxone

Question 38

The generic name of a drug is also known as the non-proprietary name (e.g. paracetamol, aspirin).? (True or False)

Answer 38

True

Question 39

Most drugs, formulated into tablets, contain 'filler' ingredients, also known as excipients? (True or False)

Answer 39

True

Question 40

1.-------- contains a two-piece hard shell, encasing powder or granules? 2._______ contains active ingredient, dissolved a solid base of glycerine or cocoa butter? 3.________ contains active ingredient dissolved in sweetened liquid? 4.________ contains active ingredient, suspended in water-based solution.? 5. ___________ contains active ingredient, formulated as greasy, semisolid emulsion of oil and water. Suppository Ointment Syrup Lotion Capsule

Answer 40

1. Capsule 2. Suppository 3. Syrup 4. Lotion 5. Ointment

Question 41

The study of the molecular, biochemical and physiologic effects of drugs on human body?

Answer 41

Pharmacodynamics

Question 42

this a protein that interacts with a physiological signal outside the cell and convert it into an effect inside cells?

Answer 42

Receptor

Question 43

Some drugs act on this type of receptors to speed up chemical reactions in the body?

Answer 43

Enzyme

Question 44

An agonist mimics the effects of a natural substance in the body called____________?

Answer 44

Ligand

Question 45

Drug affinity to receptors influence the drug?

Answer 45

potency

Question 46

this type of drug action binds to a receptor but does not active it ?

Answer 46

Antagonist

Question 47

Naloxone ( Narcan) belongs to this type of receptors that induces an opposite clinical response to an agonist?

Answer 47

Inverse agonist

Question 48

Undesirable drug effects can be defined as ?

Answer 48

adverse drug reactions

Question 49

This type of unintended effects are mostly predictable, usually mild and may resolve after commencement of therapy?

Answer 49

side effect

Question 50

This type of unintended drug reactions do not usually occur during first exposure. it can be life-threatening!?

Answer 50

Allergic reactions

Question 51

__________ can occur with regular use of some drugs, When the individual may need a higher dosage of the drug to achieve the same therapeutic effects.?

Answer 51

Tolerance

Question 52

This is a well-recognised drug effect that is unrelated to the pharmacological properties of the drug?

Answer 52

Placebo

Question 53

Change in a vital sign, commonly associated with the adverse effects of opioid overdose is _________________?

Answer 53

respiratory depression

Question 54

In rare cases, taking a new drug (e.g penicillin, aspirin) can induce this type of shock?

Answer 54

Anaphylactic

Question 55

This drug is commonly administered is cases of anaphylactic shock?

Answer 55

Adrenaline

Question 56

Drugs that drop blood pressure quickly is likely to result in this symptom?

Answer 56

Dizziness

Question 57

Laxatives or enemas may be required, if this common adverse effect of opioid therapy is not managed early with increase dietary fibre and fluid intake?

Answer 57

Constipation

Question 58

Insulin, produced by the beta cells in the pancreas, is this type of protein ?

Answer 58

transport

Question 59

The effective dose 50 (ED50) is the dose that would produce the desired effect in 50% of subjects.if your patient needs more dosage than this 50%, your patient is a______________?

Answer 59

hyporeactive drug responder

Question 60

The effective dose 50 (ED50) is the dose that would produce the desired effect in 50% of subjects.if your patient needs less dosage than is 50%, your patient is a ______________?

Answer 60

hyperreactive drug responder

Question 61

Only patients with psychological problems experience drug effects from a placebo.? (True OR False )

Answer 61

False

Question 62

Side effects are always undesirable effects experienced by the consumer of the medication.? (True or false)

Answer 62

False

Question 63

pick of the words to answer the question? 1. _________ Binds to a receptor but does not activate it ? 2 .__________ Binds to a receptor but only produces some response? 3.___________ Binds to receptor and activates it to produce a response ? 4.___________ Binds to a receptor and induces an opposite clinical response to a ligand? Antagonist Agonist Partial agonist Inverse agonist

Answer 63

1. Antagonist 2. Partial agonist 3. Agonist 4. Inverse agonist

Question 64

Potency of drug: Which of these answers are the correct one ?

Answer 64

Higher potency = morphine Mid- level potency = pethidine Lower potency= paracetamol

Question 65

Which of the following are substances or sites of drug receptors?(Hint: not the effects of drug action) (Select all the apply)?

Answer 65

Transport proteins Ion channels Enzymes

Question 66

There is variability in drug sensitivity across the lifespan? (True or False)

Answer 66

True

Question 67

A drug can alter the nature of cell functions? (True or False )

Answer 67

False

Question 68

Efficancy of drug

Answer 68

top one Higher bottom one Lower

Question 69

A drug that is an agonist has a similar mechanism of action to one of the following? inverse agonist antagonist ligand partial agonist

Answer 69

ligand

Question 70

Efficancy is the same as potency in pharmacology ? (True or False)

Answer 70

False

Question 71

Pharmacodynamics is how the body responds to the drug? (True or False?

Answer 71

True

Question 72

Which of the following factors need to be considered when administering or adjusting drug dosage? Body weight and composition Body structure Renal impairment Skin colour Liver impairment

Answer 72

Body weight and composition Renal impairment Liver impairment

Question 73

the mechanism of drug tolerance are related to: ? decreased drug sensitivity in the central nervous system increased drug sensitivity in the central nervous system increased drug breakdown by the liver decreased drug breakdown by the liver

Answer 73

decreased drug sensitivity in the central nervous system increased drug breakdown by the liver

Question 74

The more receptors are bound by the drug, the higher the intensity of effect? (True or false)

Answer 74

True

Question 75

Types of dugs inverse agonist Antagonist Partial agonist Full agonist

Answer 75

first one Full agonist second one Partial agonist third one Antagonist fourth one Inverse agonist

Question 76

unintended drug effects are often related to its lack of specificity? (True or False)

Answer 76

True

Question 77

oral candidiasis (oral thrush) is commonly caused by the following (Select all the apply):?

Answer 77

anticancer drugs corticosteroids Antibacterial drugs

Question 78

All the following are unintended drug effects EXCEPT:?

Answer 78

therapeutic effects

Question 79

Clinical manifestations of allergic reactions to drug therapy are (select all that apply):? rash bronchospasm respiratory depression insomnia cardiac arrest

Answer 79

rash bronchospasm cardiac arrest

Question 80

The most common organ in drug metabolism are the kidneys.?(True or False)

Answer 80

False