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Jenna - USMLE Step 1 Study Cards > PHARMACOLOGY: Miscellaneous > Flashcards

PHARMACOLOGY: Miscellaneous Flashcards

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USMLE® Step 1 flashcards
1
Q

You have a patient with Lesch-Nyhan syndrome being treated with allopurinol. They develop leukemia and you want to treat them with 6-mercaptopurine. Would you start with a higher dose or a lower dose?

A

Lower dose

Xanthine oxidase metabolizes purines such as 6-MP

Allopurinol inhibits xanthine oxidase.

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Jenna - USMLE Step 1 Study Cards (2 decks)

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