Pharmacology Introduction Flashcards
Routes of Administration
Oral
Most common route in veterinary medicine
Routes of Administration
Injection Sites
- Subcutaneous (SQ)
- Intradermal (ID)
- Intramuscular (IM)
- Intravenous (IV) - fastest absorption
Pharmacokinetics
Study of how drugs move within the body
* absorption
* distribution
* metabolism
* excretion
Toxicity
Adverse reaction to an administered drug
OTC
Over The Counter
* drugs do not require a prescription
Dosage
Amount of drug needed per unit of body weight
Antagonist
Drugs that bind and activate receptors
* suppress a body response
* out compete other drugs for the same receptor
Agonist
Drugs that bind and activate receptors
* produce a body response
* have a higher affinity and efficacy level
Plasma Bound
Factor that can affect drug distribution
Organs used to excrete drugs
- Liver
- Kidneys
Therapeutic Index
Numerical value that represents dose that is effective vs dose that is lethal to an animal
* larger margin = higher safety of drug