Pharmacology Introduction Flashcards
Full agonist
Produces the maximal effect from a drug
Partial agonist produces less of an effect
Receptor
Component of an organism with which a chemical interacts
Drug—-receptor—-effect
Antagonist
Produces no effect, inhibits agonist induced cell signaling events
Drug effects can be influenced by a variety of factors
Age, physiological condition, disease states, interactions with other drugs, tolerance, genetics
Drug development
Discover and preclinical testing, clinical testing, review by FDA, postmarketing surveillance
Rare toxicities are unlikely to be predicted, typically found when released to public
FDA cannot interfere with the practice of medicine, the physicians determines the se for each drug
Genetic versions are bioequivalent of the brand names