PHARMACOLOGY: GENERAL REVIEW/FARMER LECTURE Flashcards

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1
Q

What kind SYMPATHIC/ADRENERGIC receptors are on the Heart?

A

BETA 1

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2
Q

What kind of SYMPATHETIC/ADRENERGIC receptors are on the lungs?

A

BETA 2 RECEPTORS

CAUSE LUNG BRONCHI TO DILATION via smooth muscle

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3
Q
  1. What kind of SYMPATHETIC/ADRENERGIC receptors are on BLOOD VESSELS?
  2. Affect on Blood Vessels?
A
  1. ALPHA 1 RECEPTORS
  2. Constriction of Blood vessels which increases BP
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4
Q
  1. Adrenalin is also called?
  2. Where is Adrenalin produced?
  3. Produced during stressful/trauma/surgery events T or F?
A
  1. Epinephrine
  2. Adrenal glands
  3. True
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5
Q

Epinephrine & norepinephrine (neurotransmitter) affects

  1. GI
  2. Pupils
  3. Lungs

Sympathetic nervous System uses norepinephrine)

Adrenal gland (adrenal medulla) (epinenephrine) extra boast

Adreneginc neurons

Adrenergic system

A
  1. GI Shut down
  2. Pupils dilate (max info)
  3. Lungs bronchioles open
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6
Q

Adrenergic Agonists are also called?

A

sym/patho/mimetics

or

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7
Q

sym/patho/mimetics also called?

A

Adrenergic Agonists

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8
Q
  1. Albuterol is what? Used for asthma brochial constriction and spasm
  2. affect on HR and BP?
A
  1. Albuterol is an adrenergic beta 2 agonist
  2. Î Hr Î BP
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9
Q
  1. Beta Blockers also called ?
  2. are located Beta 1 on __?_ ,Beta 2 on __?_
  3. Beta Blockers are common drugs used to tx? (2)
A
  1. Adrenergic Antagonist
  2. Beta 1 on heart, B 2 on Lungs
  3. tx High BP and High eye pressure (glaucoma)
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10
Q

Beta blocker or Adrenergic Antagonist are used for asthma? T/F?

A

False

Andrenergic Antagonist cause bronchial constriction

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11
Q

Cardioselective beta blockers are used for pt with asthma

WHY?

A

Beta blockers cause brochial spasms even Beta 1 drugs

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12
Q

Effects of Parasympatheitc Tone

HR?

BP?

Digestion

A

HR and BP down

Digestion up

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13
Q

Parasympathetic system uses 2 transmitters/receptors

A

Acetylcholine (Neurotransmitters)

Muscarinic Receptors (on organs)

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14
Q

Bethanechol

Cholinergic Agonism also called Cholinomimetic

example:

Adrenergic Antagonist

Bethanechol fxn (2)

Cholinergic Muscarinic Agonist

A
  1. Stimulate Bowel and bladder fxn
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15
Q

Indirect cholinergic agonism via

ACETYLCHOLINESTERASE INHIBITORS

Cholinomimetic

  1. fxn (2)
  2. have what ending on drug name?
  3. EXAMPLE DRUG?
  4. Organophosphates are ACETYLCHOLINESTERASE INHIBITORS Toxin to humans why?
  5. What is the Organophosphate OD antedote?
A
  1. Blocks acetlycholine breakdown Which increase acetycholine concentration/levels
  2. NEO/STYGMINE
  3. NEO/STYGMINE
  4. ACETYLCHOLINE is not broken down and reach toxic levels
  5. Atropine
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16
Q

Cholinergic Antagosim

Drug example?

  • Cholinergic Muscarinic antagonist
  • anticholinergic
  • antimuscurinic
  • parasympatholytic
A
  1. Atropine
17
Q

Atropine

Cholinergic Antagosim

used to tx (5)

Antidote for?

A
  1. speed up HR
  2. Emergency tx for bradycardia
  3. Atropine causes mydnasis (open the pupils)
  4. tx diarrhea slows down GI by blocking parasympathic effect
  5. Antidote for Organophosphate poisoning
18
Q

Asthma tx DuoNeb contains two drugs

can use two class/types of drugs?

Name the two drugs?

A
  1. Beta 2 agonist/ Albulterol
  2. anticholinergic, antimuscarinic, parasympatholytic bloc/Ipratropium note “atropine” in the drug name
19
Q

Sympathic and parasympathic drugs

organs to assess for INCREASE OR DECREASE in fxn or rate? (6)

A
  1. HR
  2. BP
  3. Eye pressure
  4. Lungs: Open or closed
  5. Bladder: Tone relax or less relaxed
  6. GI: stimulated or slow
20
Q
  1. Mydriasis
  2. Name 2 class durgs to cause this
A
  1. Dilation of pupils
  2. Sympathomimetic adrenegic drugs (epinephrine) or anticholinergic parasympatholytic drugs (Atropine)
21
Q
  1. Miosis is ?
  2. 2 class drugs to cause this?
A
  1. constricting pupils
  2. sympatholytic andrenergic antagonist and cholinergic parasympathomimetic
22
Q

Dry Eye caused by

A

sympathomemetic adrenergic and anticholinergic parasympatholytics drugs

23
Q

Drugs that stimulate tears?

A

sympatholytic adrenergic antagonist drugs or

cholinergic parasympathomimetic drugs

24
Q

Dry mouth

most common side effect of medications

A

sympathomimetic adrenergic drugs or

anticholinergic parasympatholytic drugs cause dry mouth

25
Q

stimulates salivary glands

A

sympatholytic adrenergic antagonist drugs or

cholinergic parasympathomimetic drugs stimulate saliva production or acetylcholinease to raise acetlycholine levels