PHARMACOLOGY: GENERAL REVIEW/FARMER LECTURE Flashcards
What kind SYMPATHIC/ADRENERGIC receptors are on the Heart?
BETA 1
What kind of SYMPATHETIC/ADRENERGIC receptors are on the lungs?
BETA 2 RECEPTORS
CAUSE LUNG BRONCHI TO DILATION via smooth muscle
- What kind of SYMPATHETIC/ADRENERGIC receptors are on BLOOD VESSELS?
- Affect on Blood Vessels?
- ALPHA 1 RECEPTORS
- Constriction of Blood vessels which increases BP
- Adrenalin is also called?
- Where is Adrenalin produced?
- Produced during stressful/trauma/surgery events T or F?
- Epinephrine
- Adrenal glands
- True
Epinephrine & norepinephrine (neurotransmitter) affects
- GI
- Pupils
- Lungs
Sympathetic nervous System uses norepinephrine)
Adrenal gland (adrenal medulla) (epinenephrine) extra boast
Adreneginc neurons
Adrenergic system
- GI Shut down
- Pupils dilate (max info)
- Lungs bronchioles open
Adrenergic Agonists are also called?
sym/patho/mimetics
or
sym/patho/mimetics also called?
Adrenergic Agonists
- Albuterol is what? Used for asthma brochial constriction and spasm
- affect on HR and BP?
- Albuterol is an adrenergic beta 2 agonist
- Î Hr Î BP
- Beta Blockers also called ?
- are located Beta 1 on __?_ ,Beta 2 on __?_
- Beta Blockers are common drugs used to tx? (2)
- Adrenergic Antagonist
- Beta 1 on heart, B 2 on Lungs
- tx High BP and High eye pressure (glaucoma)
Beta blocker or Adrenergic Antagonist are used for asthma? T/F?
False
Andrenergic Antagonist cause bronchial constriction
Cardioselective beta blockers are used for pt with asthma
WHY?
Beta blockers cause brochial spasms even Beta 1 drugs
Effects of Parasympatheitc Tone
HR?
BP?
Digestion
HR and BP down
Digestion up
Parasympathetic system uses 2 transmitters/receptors
Acetylcholine (Neurotransmitters)
Muscarinic Receptors (on organs)
Bethanechol
Cholinergic Agonism also called Cholinomimetic
example:
Adrenergic Antagonist
Bethanechol fxn (2)
Cholinergic Muscarinic Agonist
- Stimulate Bowel and bladder fxn
Indirect cholinergic agonism via
ACETYLCHOLINESTERASE INHIBITORS
Cholinomimetic
- fxn (2)
- have what ending on drug name?
- EXAMPLE DRUG?
- Organophosphates are ACETYLCHOLINESTERASE INHIBITORS Toxin to humans why?
- What is the Organophosphate OD antedote?
- Blocks acetlycholine breakdown Which increase acetycholine concentration/levels
- NEO/STYGMINE
- NEO/STYGMINE
- ACETYLCHOLINE is not broken down and reach toxic levels
- Atropine
Cholinergic Antagosim
Drug example?
- Cholinergic Muscarinic antagonist
- anticholinergic
- antimuscurinic
- parasympatholytic
- Atropine
Atropine
Cholinergic Antagosim
used to tx (5)
Antidote for?
- speed up HR
- Emergency tx for bradycardia
- Atropine causes mydnasis (open the pupils)
- tx diarrhea slows down GI by blocking parasympathic effect
- Antidote for Organophosphate poisoning
Asthma tx DuoNeb contains two drugs
can use two class/types of drugs?
Name the two drugs?
- Beta 2 agonist/ Albulterol
- anticholinergic, antimuscarinic, parasympatholytic bloc/Ipratropium note “atropine” in the drug name
Sympathic and parasympathic drugs
organs to assess for INCREASE OR DECREASE in fxn or rate? (6)
- HR
- BP
- Eye pressure
- Lungs: Open or closed
- Bladder: Tone relax or less relaxed
- GI: stimulated or slow
- Mydriasis
- Name 2 class durgs to cause this
- Dilation of pupils
- Sympathomimetic adrenegic drugs (epinephrine) or anticholinergic parasympatholytic drugs (Atropine)
- Miosis is ?
- 2 class drugs to cause this?
- constricting pupils
- sympatholytic andrenergic antagonist and cholinergic parasympathomimetic
Dry Eye caused by
sympathomemetic adrenergic and anticholinergic parasympatholytics drugs
Drugs that stimulate tears?
sympatholytic adrenergic antagonist drugs or
cholinergic parasympathomimetic drugs
Dry mouth
most common side effect of medications
sympathomimetic adrenergic drugs or
anticholinergic parasympatholytic drugs cause dry mouth
stimulates salivary glands
sympatholytic adrenergic antagonist drugs or
cholinergic parasympathomimetic drugs stimulate saliva production or acetylcholinease to raise acetlycholine levels