Pharmacology for Psychosis Flashcards
Was there any treatment for psychosis before the 1930’s
Before the 1930’s there were no effective treatments for any of the so-called ‘functional psychosis’
What was the main function of psychiatric hospitals
The main function of psychiatric hospitals were to keep patients at tolerable health and comfort
What were nurses called
Nurses at the time were called attendants, they did not have a clinical role and only followed doctors orders
Who developed Insulin Therapy
Sakel developed insulin therapy in 1927
What is Insulin Therapy and when was it used
Insulin Therapy involves administering insulin to induce a coma, this was widely used in the 1940’s and 1960’s
Who developed the lobotomy
The Lobotomy was pioneered by Moniz between 1874-1955
What was believed about patients who were experiencing psychosis
It was believed that people experiencing psychosis had abnormal neural connections in their frontal lobes
What happened during a lobotomy
The frontal lobes of the patients were then cut or severed, this left people with severe and disabling impairments
What reductions were seen in patients after a lobotomy
Reductions were seen in responsiveness, self-awareness, control and sponaenity.
Where is the Electroconvulsive therapy suite in the mid-west
UHL has the only ECT suite in the mid-west region
What does ECT involve
ECT involves a brief electrical impulse being sent into the brain while the patient is under anaesthetic to stimulate a seizure
What is ECT used for
ECT is used for mania and depression but can also be used for catatonia
What was the first antipsychotic
Chlorpromazine was the first antipsychotic developed
Where was chlorpromazine developed
Chlorpromazine was founded in a laboratory when searching for antihistamines
Who used chlorpromazine first and for what and what did he find
Henri Loborit used chlorpromazine as part of a sedative cocktail for surgical patients but found it did not work the same as other sedatives as the patients were still functional
