Pharmacology For Pathology Flashcards
ADHD
Stimulants (methylphenidate amphetamine)
Alcohol withdrawal
Benzodiazepines (choldiazepoxide Lorazepam diazepam
Bipolar disorder
Lithium
Valproic acid
Atypical antipsychotics
Bulimia nervosa
SSRI
Depression
SSRI
Generalize anxiety disorder
SSRI
SNRI
Obsessive compulsive disorder
SSRI
Venlafaxine
Clomipramine
Panic disorder
SSRI
Venlaflaxine
Benzodiazepines
PTSD
SSRI
Venlafalxine
Schizophrenia
Atypical antipsychotics
Social anxiety disorder
SSRI
Venlaflaxine
Performance only: beta blockers benzodiazepines
Tourette syndrome
Antipsychotics (fluphenazine pimozine)
Bupropion
Increase NE and DA
Smoking cessation
Toxicity: stimulant effect (taquicardia, insomnia) headache seizure(in bulimic and anorexic patients )
Mirtazapine
Alpha 2 antagonist
Increase NE and 5HT
Toxicity: sedation ( good in patients with insomnia )
Increase appetite
Weight gain (in elderly and anorexic patients)
Dry mouth
Trazadone
Block: 5HT, alpha-1, H1
Use primary in insomnia (high doses needed for antidepressant )
Toxicity: sedation, nausea, priapism postural hypotension.
Varenicline
AcH-nicotinic partial agonist
Smoking cessation
Toxicity: sleep disturbance
Pentazocine
Kappa agonist
Miu antagonist
Severe pain
Opioid withdrawal symptoms if taking full opiod antagonist
Butorphanol
Kappa agonist
Miu partial agonist
Less respiratory depression than full agonist
Withdrawal symptoms if full opiod agonist
Memantine
NMDA receptor antagonist
Use in Alzheimer disease
Side effects : dizziness confusion hallucination
Tetrabenazine and reserpine
Inhibits vesicular monoamine transporter VMAT- decrease dopamine vesicles package
Riluzone
Tto in ALS
Decrease glutamate exocitotoxicity
Triptans
Serotonin 1B/1D agonist
Inhibit CN V
Decrease vasoactive peptide release
Induce vasoconstriction
