Pharmacology for delirium/dementia

Question 1

olanzapine (Zyprexa) action

Answer 1

Delirium

Question 2

olanzapine (Zyprexa) onset, peak, duration for PO

Answer 2

O: unknown
P: 6h
D: unknown

Question 3

olanzapine (Zyprexa) onset, peak, and duration for IM

Answer 3

O: rapid
P: 15-45 m
D: 2-4 h

Question 4

haloperidol (Haldol) action

Answer 4

Delirium

Question 5

haloperidol (Haldol) onset, peak, and duration for PO

Answer 5

O: 2 h
P: 2-6 h
D: 8-12 h

Question 6

haloperidol (Haldol) onset, peak, and duration for IM

Answer 6

O: 20-30m
P: 30-45 m
D: 4-8 h

Question 7

haloperidol (Haldol) onset, peak, and duration for IV/dose

Answer 7

All: unlabeled use

Give 0.5 mg - 5 mg every 30 m for acute psychosis/delirium.

Question 8

Typical dosing for olanzapine

Answer 8

5-10 mg/day - 20 mg/day

Question 9

Side effects for olanzapine

Answer 9

orthostatic hypotension, dry mouth, sedation, weakness, insomnia, tardive dyskinesia

Question 10

Side effects for Haldol

Answer 10

dry mouth, orthostatic hypotension, constipation, dizziness. Long time use may result in tardive dyskinesia

Question 11

donepezil (Aricept) action

Answer 11

Dementia

Question 12

donepezil (Aricept) onset, peak, and duration for PO

Answer 12

O: Unknown
P: several weeks
D: 6 weeks

Question 13

donepezil (Aricept) dosing

Answer 13

5 mg-10 mg a day (after 4-6 weeks)

Question 14

Side effects of donepezil (Aricept)

Answer 14

insomnia, headache, fatigue, dreaming, dizziness, GI upset

Question 15

memantine (Namenda) action

Answer 15

dementia

Question 16

memantine onset, peak, and duration for PO

Answer 16

O: unknown
P: 3-7 hours
D: 12 hours

Question 17

memantine (Namenda) dosing

Answer 17

5 mg once daily - 10 mg daily

Question 18

side effects of Namenda

Answer 18

dizziness, headache, constipation

Question 19

lorezapam (Ativan) action

Answer 19

anxiety related to dementia

Question 20

lorezapam (Ativan) onset, peak and duration for PO

Answer 20

O: 15-60m
P: 1-6 h
D: 8-12 h

Question 21

lorezapam (Ativan) onset, peak and duration for IM

Answer 21

O: 30-60m
P: 1-2 h
D: 8-12 h

Question 22

lorezapam (Ativan) onset, peak and duration for IV

Answer 22

O: 15-30 m
P: 15-20 m
D: 8-12 m

Question 23

lorezapam (Ativan) can be given sublingual (T/F)

Answer 23

T. Has a rapid absorption

Question 24

dosing for lorezapam (Ativan)

Answer 24

Always start with the lowest dose of 0.5 mg

Question 25

Side effects of lorezepam (Ativan)

Answer 25

drowsiness, dizziness, Gi upset, hypotension