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Pharmacology Exam 2 > Pharmacology exam two respiratory tract and Anticoagulant drugs > Flashcards

Pharmacology exam two respiratory tract and Anticoagulant drugs Flashcards

1
Q

What are the three Anti- inflammatory agents?

A
  • Glucocorticoids
  • Leukotriene Modifiers
  • Mast Cell Stabilizers
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2
Q

Examples of Glucocorticoids (anti-inflammatory agent)

A
  • Budesonide
  • Fluticasone
  • Methylprednisolone (IV)
  • Prednisone (oral)
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3
Q 
Mechanism of Action for ?
Budesonide
fluticasone
Methylprednisolone (IV)
Prednisone (oral)
A
  • Suppress INFLAMMATION
  • Decreases synthesis and release of inflammatory mediators.
  • Decreases infiltration and activity of inflammatory cells.
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4
Q 
Anti-inflammatory agents 
glucocorticoids 
(What is the Therapeutic Effects of the following?)
Budesonide
Fluticasone
Methylprednisolone(IV)
Prednisone(oral)
A

Therapeutic effects are:

  • Reduces bronchial hyperreactivity
  • Decreases mucus production
  • Increases number/responsiveness of beta-2 receptors
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5
Q

Anti-inflammatory agents (glucocorticoids)
What are the Adverse Effects of the following?
Budesonide
Fluticasone
Methylprednisolone (IV)
Prednisone(oral)

A

Adverse effects are:

  • Thrush
  • Severe long-term side effects: adrenal suppression, osteoporosis, hyperglycemia
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6
Q 
Anti-inflammatory (Glucocorticoids) 
What are the Nursing Considerations for the following?
Budesonide
Fluticasone
Methylprednisolone(IV)
Prednisone(oral)
A

Nursing Considerations are:

  • Most effective anti-asthma drugs (when used properly).
  • Rinse mouth after each inhalation dose.
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7
Q

Examples of Leukotriene Modifiers (anti-inflammatory agents)

A
  • Zileuton (Zyflo)
  • Zafirlukast (Accolate)
  • Montelukast (Singulair)
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8
Q

What is the mechanism of action for the following:
Zileuton (Zyflo)
Zafirlukast (Accolate)
Montelukast (Singulair)

A

Mechanism of action

  • Suppress effects of leukotrienes
  • Target leukotrienes (inflammatory mediators)
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9
Q

What are the therapeutic effects of the following:
Zileuton (Zyflo)
Zafirlukast (Accolate)
Montelukast (Singulair)

A

Therapeutic Effects (same as Glucocorticoids)

  • Reduces bronchial hyperreactivity
  • Decreases mucus production
  • Increases number/responsiveness of beta-2 receptors.
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10
Q

what are the adverse effects of the following:
Zileuton (Zyflo)
Zafirlukast (Accolate)
Montelukast (Singulair)

A

Adverse Effects:

  • Risk for liver damage
  • Dyspepsia
  • Churg-Strauss Syndrome
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11
Q

What are the drug interactions for the following:
Zileuton (Zyflo)
Zafirlukast (Accolate)
Montelukast (Singulair)

A

Drug Interactions are:

  • Theophylline and propranolol
  • Food (Accolate only)
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12
Q

what are the nursing considerations for the following:
Zileuton (Zyflo)
Zafirlukast (Accolate)
Montelukast (singulair)

A

Nursing Considerations

- Less effective than glucocorticoids

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13
Q

Examples of mast cell stabilizers (anti-inflammatory agents)

A

Cromolyn (inhalation, nebulizer, MDI-metered dose inhaler)

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14
Q

What is the mechanism of action for

Cromolyn (anti-inflammatory agent) ?

A

Mechanism of action

-Targets and inactivates mast cells.

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15
Q

What are the therapeutic effects of Cromolyn?

A

Therapeutic effects

- Suppresses inflammation (not a bronchodilator)

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16
Q

What are the adverse effects of Cromolyn?

A

Adverse Effects

  • Cough
  • Risk for bronchospasm
  • Safest of all anti-asthma meds
17
Q

What are the nursing considerations for Cromolyn (anti-inflammatory agent mast cell stabilizer)?

A

Nursing considerations

  • Slow-acting-not for quick relief, used for prophylaxis
  • Cannot be used in patients with liver or kidney damage.
18
Q

What are the types of bronchodilators?

A
  • Beta-2 adrenergic agonists

- Methylxanthines

19
Q

What are examples of the short acting bronchodilators?

A

SABA

  • Albuterol
  • Xopenex
20
Q

What are examples of long acting bronchodilators?

A

LABA

  • Salmeterol
  • Formoterol
21
Q

What is the mechanism of action for SABA and LABA bronchodilators?

A

Mechanism of action

  • Sympathomimetic drugs that produce selective activation of beta-2 adrenergic receptors.
  • Activate beta-2 receptors in smooth muscle of lung

Pharmacology Exam 2 (1 decks)

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