Pharmacology by Class

Question 1

Anticholinergic

Answer 1

ATROPINE

Question 2

Atropine Substitutes

Answer 2

TRIHEXYPHENIDYL, BENZTROPINE
IPRATROPIUM BROMIDE (M3)
TIOTROPIUM BROMIDE (M1)
HOMATROPINE
CYCLOPENTOLATE
TROPICAMIDE
GLYCOPYRROLATE
HYOSCINE
DICYCLOMINE
OXYBUTYNIN
TOLTERODINE

Question 3

Reversible Anti-Cholinesterase Drugs

Answer 3

Short-Acting: EDROPHONIUM
Medium-Acting: NEOSTIGMINE, PYRIDOSTIGMINE
Long-Acting: PYRIDOSTIGMINE, TACRINE, AMBEONIUM
DEMECARIUM

Question 4

Irreversible Anti-Cholinesterase Drugs

Answer 4

Organophosphorus Compounds:
-PARATHION, MALATHION
-DIAZINON (TIK-20)
-ECHOTHIOPHATE
-SOMAN
-SARIN
-TABUN
Carbonates:
-CARBARYL
-PROPAXUR

Question 5

Cholinesterase Reactivators

Answer 5

Oximes: PRALIDOXIME (PAM)

Question 6

Directly-Acting Cholinergic Agonists

Answer 6

Choline Esters: ACETYLCHOLINE, METHACHOLINE, CARBACHOL, BETHANECHOL
Cholinomimetic Alkaloids: PILOCARPINE, ARECHOLINE

Question 7

Indirectly-Acting Cholinergic Agonists

Answer 7

Reversible: NEOSTIGMINE (ME), PHYSOSTIGMINE (ME), PYRIDOSTIGMINE (L), EDROPHONIUM (S), DONEPEZIL
Irreversible: ORGANOPHOSPHATES, CARBAMATES

Question 8

Competitive (Non-depolarizing) Nicotinic Muscle Receptor Blockers (IV, does NOT cross BBB)

Answer 8

Long-Acting: TUBOCURARINE, PANCURONIUM, PIPECURONIUM, DOXACURIUM, METOCURINE
Intermediate: VECURONIUM, ROCURONIUM, ATRACURIUM
Short-Acting: MIVACURIUM

Question 9

Noncompetitive (Depolarizing) Nicotinic Muscle Receptor Blockers (IV, does NOT cross BBB)

Answer 9

SUCCINYLCHOLINE

Question 10

Directly-Acting Skeletal Muscle Relaxants

Answer 10

DANTROLENE

Question 11

Central Skeletal Muscle Relaxants

Answer 11

MEPHENESIN
CHLORZOXAZONE
CARISOPRODOL
METHOCARBAMOL

BENZODIAZEPINES

GABA derivatives: BACLOFEN

Question 12

Ganglionic Blockers

Answer 12

MECAMYLAMINE
TRIMETHAPHAN
HEXAMETHONIUM
NICOTINE

Question 13

MAO-A Inhibitors

Answer 13

PHENELZINE

TRANYLCYPROMINE

Question 14

MAO-B Inhibitors

Answer 14

SELEGILINE

Question 15

COMT Inhibitors

Answer 15

Long-Acting: TOLCAPONE
Short-Acting: ENTACAPONE

METYROSINE
RESERPINE
AMPHETAMINE
TYRAMINE
COCAINE
IMIPRAMINE

Question 16

Direct Adrenergic Agonists

Answer 16

EPINEPHRINE: alpha1, alpha2, beta1, beta2
NOREPINEPHRINE: alpha1, alpha2, beta1
ISOPROTERENOL: beta1, beta2
DOPAMINE: D1, D2 > beta > alpha
                    FENOLDOPAM
                    DOPEXAMINE

Question 17

Selective beta1 Agonists

Answer 17

DOBUTAMINE

Question 18

Selective alpha1 Agonists

Answer 18

PHENYLEPHRINE

METHOXAMINE

Question 19

Selective alpha2 Agonists

Answer 19

Centrally-Acting: CLONIDINE
Won’t Cross Placenta: METHYLDOPA

GUANFACINE
GUANABENZ

TIZANDINE

Question 20

Selective beta2 Agonists

Answer 20

SABA: ALBUTEROL/LEVALBUTEROL/PIRBUTEROL
            TERBUTALINE
            METAPROTERENOL
LABA: SALMETEROL
            FORMOTEROL

Question 21

First Generation H1 Antagonists

Answer 21

DIPHENHYDRAMINE
DIMENHYDRINATE (DRAMAMINE)
PROMETHAZINE
HYDROXYZINE
CHLORPHENIRAMINE
CYCLIZINE
MECLIZINE
DOXYLAMINE
CYPROHEPTADINE
DOXEPIN

Question 22

5-HT Agonists

Answer 22

BUSPIRONE
CISAPRIDE
SUMATRIPTAN
TEGASEROD

Question 23

5-HT Antagonists

Answer 23

CLOZAPINE
CYPROHEPTADINE (1st generation)
METHYLSERGIDE
ONDANSETRON

Question 24

Opiates

Answer 24

CODEINE
HYDROCODONE
HYDROMORPHONE
DEXTROMETHORPHAN
BENZONATATE
DIPHENHYDRAMINE (1st generation H1 antagonist)

Question 25

Anti-Emetics

Answer 25

``` ONDANSETRON GRANISETRON DOLASETRON PROCHLORPERAZINE DEXAMETHASONE METHYLPREDNISOLONE DRONABINOL/NABILONE DIPHENHYDRAMINE/MECLIZINE APREPITANT BENZODIAZEPINES ```

Question 26

Cholinergic Agonists

Answer 26

``` Directly Acting Choline Esters: Short-Acting: -METACHOLINE (M) -BETHANECHOL (M) -CARBACHOL (M & N) Cholinomimetic Alkaloids: Long-Acting: -PILOCARPINE (M) -ARECHOLINE ```