Pharmacology - Antianginals Flashcards
1
Q
Nitrates are prodrugs of:
A
Nitric oxide
2
Q
MOA: Nitrates
A
vasodilators –> decrease preload;
decrease oxygen requirements
3
Q
Use: Nitrates
A
Can decrease infarct size and post-MI mortality;
For acute angina
4
Q
Class: Isosorbide
A
Nitrate
**for chronic use
5
Q
Class: Nitroglycerin
A
Nitrate
**for acute use
6
Q
Nitrates are 100% contraindicated with use of what drug?
A
Sildenafil (PDE-5 inhibitor) for ED;
cause a massive drop in BP
