Pharmacology Flashcards
What is the MOA of Penicillin?
Bactericidal via beta-lactam blocking peptidoglycan synthesis in bacterial cell wall
What are the ADR’s of Penicillin?
Angioedema, diarrhoea, fever, hypersensitivity reaction, joint pains, rashes, anaphylaxis
What are the CI’s of Penicillin?
Previously sensitive to beta-lactam antibiotics
What is the MOA of Ciproflaxacin?
Bacteriostatic via quinolone acting as tropoisomerase inhibitor = no bacterial DNA replication
What are the ADR’s of Ciproflaxacin?
Diarrhoea, dizziness, headaches, nausea, vomiting, achilles tendon rupture
What are the CI’s of Ciproflaxacin?
Previous sensitivity or tendon rupture
What is the MOA of Daptomycin?
Bactericidal by drug inserting into bacterial cell membrane -> ion pores = depolarise + kill bacteria
What are the ADR’s of Daptomycin?
Abd. pain, GI disturbances, anaemia, rash
What are the CI’s of Daptomycin?
Pregnant