PHARMACOLOGY Flashcards
Antiemetic that is contraindicated in patients wih seizure
Meperidine
What group of anesthetic drug that are CI in patients wih Myasthenia Gravis
Neuromuscular Blockers
Active metabolite in Meperidine that causes Seizure
Normeperidine
DOC for Myasthenia Gravis
Neostigmine
C/I in porphyria
Barbiturates
Anticholinergic to be used in caution in patienta with BPH
Ipatropium bromide
Cholinergic drug that can be used in Post-Op urinary problems
Bethanecol
In these drugs, we avoid cheese, whine or tyramine containig foods bec it causes hypetensive crisis
MAOIs
Patients wih parkinsons disease should take this drug with caution due to EPS
METOCLOPRAMIDE
CINNARIZINE
2 preop prophylaxis for CV surgery
Cefazolin
Cefuroxime
Carbapenem CI to pt with seizure
Imipenem
Prophylaxis for Gastroduodenal area, small intestine, non-obstructed
Cefazolin
Anesthetic used in caution in patirnts wih liver cirrhosis
Halothane
Prophylaxis for Biliary tract: open procedure, laparoscopic high risk
Cefazolin Cefoxitin Ampicillin sulbactam Ceftriaxone Cefotetan
Prophylaxis for Biliay tract:laparoscopic low risk
None
Prophylaxis for Uncomplicated Appendicitis
Cedfazolin + Metronidazole
Cefoxitin
Cefotetan
Drugs that causes malignant hyperthermia
Halothane
Succinylcholine
Prophylaxis for Colorectal surgery
Obstructed small intestine
Cefazolin/Ceftriaxone + Metronidazole Ertapenem Cefoxitin Ampicillin sulbactam Neomycin (Nichol's preparation)
Prophylaxis for neurosugical procedures
Cefazolin
Prophylaxis for breast and hernia
Cefazolin
Prophylaxis for Orthopedic Surgery
Cefazolin/ Ceftriaxone
Most cardiotoxic anesthetic
Bupivacaine
Elective colorectal sugery
OMBP
Nichols Condon Preparation
Consists of Neomycin and erythromycin given a day prior to colorectal surgery
What has been substituted for erythromycin bec of its effectiveness against anaerobic organisms in the gut?
Metronidazole
Given prior to thyroid surgery to decrease vascularity and size of thyroid gland
Lugol’s iodine/ SSKI
Given orior to thyroid surgey to control adrenergic symptoms
Propanolol
Causes fetal hydantoin syndrome
Phenytoin
Causes ftal renal agenesis
ACE inhibitors
Cough in ACE-I is due to what substance?
Bradykinin
Medical prophylaxis
Gonorrhea
Ceftriaxone
Medical prophylaxis
Meningococcal infection
Rifampin
Minocycline
Ciprofloxacin
Medical prophylaxis
Pneumocystis carinii
TMP SMX
Aerosolized pentamidine
Medical prophylaxis
Syphilis
Benzathine penicillin G
Medical prophylaxis
TB
Isoniazid
Medical prophylaxis
Infective endocarditis in patients undergoing Dental procedures
Amoxicillin
Medical prophylaxis
Leptospirosis
Doxycycline
Medical prophylaxis
DVT
LMW heparin (Enoxaparin)
Antiplatelet of choice for secondary stroke prevention
Aspirin (inhibits COX, TxA2)
Migraine prophylaxis
Flunarizine
Propanolol
Lamotrigine (Steven-Johnsons’s syndrome)
GI upset Skin rashes Headaxhe Dizziness Closure of epiphyseal plates in children
Fluoroquinolones
Rash
Pseudomembranous colitis
Ampicillin
Teratogenic
Carcinogenic
Headaches
Confusion
Griseofulvin
Foscarnt toxicity
Nephrotoxicity
Ganciclovir toxicity
Nephrotoxicity
Leukopenia/Neutropenia
Thrombocytopenia
Toxic effects of TMP
Granulocytopenia
Leukopenia
Megaloblastic anemia
Toxic effects of Azoles (keto and fluconazole)
Gynecomastia
Liver dysfunction
Toxic effects of acyclovir
Nephrotoxicity
Delirium
Tremors
Digitalis toxicity is increased by
Hypokalemia
Hypomagnesemia
Hypercalcemia
Yellow perception
Gynecomastia
Hallucinations
Non specific symptoms
Digitalis toxicity
Anti arrhythmics that causes torsades de pointes
Sotalol
Bepridil
Drugs causing pulmonary fibrosis
Bleomycin
Amniodarone
Busulfa
Prophylaxis for head and neck surgery: clean contaminated
Cefazolin/Cefuroxime + Metronidazole
Ampicillin Sulbactam
DOC for chloroquine sensitive P. Falciparum
Chloroquine
DOC for Chloroquine-resistant Malaria
Quinine
MOA for Quinine
Forms complexes with plasmodium DNA and prevents strand separation
Used in prophylaxis and treatment of chloroquine resistant p. Falciparum
Mefloquine
Used in prophylaxis and treatment of chloroquine resistant p. Falciparum
Mefloquine
DOC for Tpxoplamosis
Pyrimethamine-Sulfadoxine (Fansidar)
Used in relapsing malaria, eradicates liver stages of P. Vivax and P. Ovale
Primaquine