Pharmacology

Question 1

Loading Dose

Answer 1

Initial dose given to get drug concentration to therapeutic range within a short period.

Question 2

1 unit = ? mls

Answer 2

0.1 ml

Question 3

Parenteral

Answer 3

Route other than GI

Question 4

Onset of Action

Answer 4

Begins when drug enters plasma and starts taking effect

Question 5

Six Patient Rights

Answer 5

Right Drug, Dose, Time, Route, Patient, and Document

Question 6

Therapeutic Index (Margin of Safety)

Answer 6

The ability of a drug to produce the desired effect with minimal or no toxicity.

Question 7

Lethal Dose

Answer 7

(LD50)- dose that kills 50% of receiving animals

Question 8

Effective dose

Answer 8

(ED50)- dose that produces desired effect in 50% of receiving animals

Question 9

The FDA does not cover these:

Answer 9

biologics and pesticides

Question 10

Half Life

Answer 10

Time required for the amount of drug in the body to be reduced by half its original level.

Question 11

Primary sites of drug excretion

Answer 11

kidneys, liver

Question 12

Glucuronyl Transferase

Answer 12

Enzyme that helps dogs and humans use aspirin- cats have much less of this

Question 13

Conjugation

Answer 13

Reaction that breaks down drug to allow it to bond with glucuronic acid

Question 14

Reduction

Answer 14

Gaining an electron resulting in negative charge

Question 15

Oxidation

Answer 15

Loss of an electron resulting in a positive charge