Pharmacology Flashcards
Agonists
Epi, NE, Clonadine
Epi action
A1: constrict
B1: Iono, chrono, dromo
B2: dilate
Epi Therapy
Broncospasm and vasoconstriction with local anesthetic
Epi pharmacokinetics
rapid
quickly degraded
IM or IV (faster)
Epi adverse effects
CNS: fear, anxiety, tension, tremor, arrhythmia
Antagonist to Insulin
NE action
A1: constricts -> inc Bp -> vagal response -> reflex bradycardia (M2)
NE Therapy
shock
NE Adverse Effects
Anxiety, fear, tremor, skin problem
Clonadine Action
A2: decreases sympathetic outflow from CNS
Clonadine Therapy
withdrawal
HBP
Antagonists (sympatholytics, blockers)
Prazosin
propranolol
Prazosin Action
A1: equilibrium antagonist
Decrease TPR w/o affecting CO
Prazosin Therapy
HBP
benign prostatic hyperplasia
Prazosin Adverse Effects
1st dose: orthostat hypotension
sexual dysfunction
antihypertension side effects with sildenafil or nitrates
Propranolol Action
B1: blocker (SA & AV)
decreases CO
bradycardia
Decreases TPR with prolong use