Pharmacology

Question 1

BUZZER

Modafinil is a drug used to treat what disorder?

Answer 1

Narcolepsy

Question 2

BONUS

What is the class of drug for Modafinil and what is its MOA?

Answer 2

Sympathomimetic and blocks reuptake of dopamine

Question 3

BUZZER

Decreased intestinal motility, constriction of pupils, decreased salivation, HTN, and smooth muscle contraction are associated with stimulation of what receptor?

Answer 3

Alpha-1 receptors

Question 4

BONUS

List 3/5 places that alpha-1 receptors are found?

Answer 4

1. Arterioles/Veins
2. Glands
3. Urinary tract smooth muscle
4. Eyes
5. Intestine

Question 5

BUZZER

Decreased NE release, DEC secretion from beta islet cells of pancreas, and DEC sympathetic outflow from the brain are all effects of what class of medications?

Answer 5

Alpha-2 receptor agonists

Question 6

BONUS

List 2 contraindications to Modafinil?

Answer 6

1. Bipolar disorder

2. CVD disease

Question 7

BUZZER

Tachycardia, INC renin secretion, INC cardiac contractility, and INC cardiac output are all effects of what receptor?

Answer 7

Beta-1 receptors

Question 8

BUZZER

Relaxation of the bronchioles/trachea and uterus as well as dilation of arterioles and veins are effects of what class of medication?

Answer 8

Beta-2 receptor agonists

Question 9

BUZZER

Non-specific beta blockers and beta-1 blockers are both?

Answer 9

Beta antagonists

Question 10

BUZZER

What receptors does Epinephrine binds to?

Answer 10

Alpha and Beta

Question 11

BONUS

What is Epinephrine’s effect on the metabolic system?

Answer 11

Glycogenolysis and Gluconeogenesis

Question 12

BONUS

Give 3 clinical uses for Epinephrine?

Answer 12

1. Bronchodilation
2. Anaphylaxis
3. Keep anesthetic in surgical area longer via blood vessel dilation

Question 13

BUZZER

What cholinesterase inhibitor is used to Tx Alzheimer’s dementia?

Answer 13

Rivastigmine

Question 14

BONUS

List 3 conditions that may be contraindications in the prescription of Rivastigmine?

Answer 14

1. Hx of seizures
2. Asthma/COPD
3. Cardiac conduction defects (i.e. Sick Sinus Syndrome, Bradyarrhythmias)

Question 15

BUZZER

Atropine should NOT be used in what condition?

Answer 15

Acute closed angle glaucoma

Question 16

BUZZER

What is the antidote to Cholinesterase inhibitor poisoning?

Answer 16

Atropine

Question 17

BONUS

Tachycardia, Tremors, Insomnia, Urinary retention, and appetite suppression are side effects from what class of drug?

Also may include Arrhythmias, HTN, Palpitations, HA, Restlessness, Difficult/painful urination

Answer 17

Sympathomimetic

Question 18

BUZZER

What substance is decreased in the body when given the parasympatholytic/muscarinic agonist Atropine?

Answer 18

Ach

Question 19

BONUS

What is Epinephrine’s effect on the Pulmonary system?

Answer 19

Bronchodilation from beta receptors

Vasoconstriction and DEC secretions from alpha receptors

Question 20

BONUS

What is Epinephrine’s effect on the Cardiac system?

Answer 20

INC heart rate & contractility

Question 21

BONUS

What is Epinephrine’s effect on the vascular system?

Answer 21

Low dose: dilates vessels

High dose: constrict vessels