Pharmacology

Question 1

ANS Receptor effects

Heart

Answer 1

M2: decrease HR, decrease contractility, decrease AV node conduction
B1: increase HR/contractility

Question 2

ANS Receptor effects

blood vessels

Answer 2

M3: vasodilation
a1: vasoconstriction
B2: vasodilation

Question 3

ANS Receptor effects

Blood pressure

Answer 3

M3: decrease BP
a1, b1: increase BP
b2: decreare BP

Question 4

ANS Receptor effects

Lung

Answer 4

M3: bronchoconstriction
B2: bronchodilation

Question 5

ANS Receptor effects

Temperature Regulation

Answer 5

M3: increase sweating

Question 6

ANS Receptor Effects

Eye

Answer 6

M3: miosis, accomodation (near vision), increase aqueous humor outflow
B1, B2: increase humor output, increase intraocular pressure

Question 7

ANS Receptor Effects

GI/GU

Answer 7

M3: increase salivation, increase detrusor contraction (increase urine flow), increase GI motility
B2, B3: detrusor muscle relaxation
a1: close sphincter (increase continence)
B2: uterine relaxation

Question 8

ANS Receptor Effects

CNS

Answer 8

M1: memory, cognition, meovement
a1: vigilance, focus

Question 9

ANS Receptor Effects

NMJ

Answer 9

Nm: Muscle Contraction
B2: muscle tremors

Question 10

Cholinergic (PNS) Agonists

Answer 10

Pilocarpine/Bethanechol (M)
Neostigmine/Pyridostigmine (indirect)
Edrophonium/Donepezil (indirect)
Organophosphate Nerve Gases (indirect)

Question 11

Conlinergic (PNS) Antagonists

Answer 11

Atropine-Scopolamine-Benztropine (M)
Oxybutynin-Tolterodine (M)
Ipratropium-Tiotropium (M)
Atracurium-Rocuronium-Succynylcholine (Nm)

Question 12

Adrenergic (SNS) Agonists

Answer 12

Epinephrine (a1-a2-b1-b2)
Norepinephrine (a1-a2-b1)
Isoproterenol (b1-b2)
Albuterol (b2)
Phenylephrine (a1)
Pseudoephedrine (indirect)
Dobutamine (b1)
dopamine (d1 + indirect)

Question 13

Adrenergic (SNS) Antagonists

Answer 13

Doxazosin-Terazosin-Prazosin (a1)
Metoprolol-Atenolol (b1)
Propranolol (b1-b2)
labetalol-carvedilol (a1-b1-b2)
clonidine (a2 agonist)

Question 14

Pilocarpine

Answer 14

Muscarininc Agonist

Question 15

Bethanechol

Answer 15

Muscarinic Agonist

Question 16

Neostigmine

Answer 16

indirect muscarinic agonist

AChE inhibitor, intermediate to long acting, reversible

Question 17

Pyridostigmine

Answer 17

indirect muscarinic agonist

AChE inhibitor, intermediate to long acting, reversible

Question 18

Edrophonium

Answer 18

indirect muscarinic agonist

AChE inhibitor, short acting, reversible

Question 19

Donepezil

Answer 19

indirect muscarinic agonist

Question 20

Organophosphate nerve gases

Answer 20

indirect muscarinic agonist

Question 21

Atropine

Answer 21

Muscarinic antagonist

Question 22

Scopolamine

Answer 22

Muscarinic antagonist

Question 23

Benztropine

Answer 23

Muscarinic antagonist

increased CNS activity

Question 24

Oxybutynin

Answer 24

Muscarinic antagonist

increased CNS activity

Question 25

Tolterodine

Answer 25

Muscarinic antagonist | increased CNS activity

Question 26

Ipratropium

Answer 26

Muscarinic antagonist

Question 27

Tiotropium

Answer 27

Muscarinic antagonist

Question 28

Atracurium

Answer 28

Nm antagonist

Question 29

Rocuronium

Answer 29

Nm antagonist

Question 30

Succinylcholine

Answer 30

Nm antagonist

Question 31

Epinephrine

Answer 31

a1-a2-b1-b2 agonist

Question 32

Norepinephrine

Answer 32

a1-a2-b1 agonist

Question 33

Isoproterenol

Answer 33

b1-b2 agonist

Question 34

Albuterol

Answer 34

b2 agonist

Question 35

Phenylephrine

Answer 35

a1 agonist

Question 36

Pseudoephedrine

Answer 36

a1 indirect agonist

Question 37

Dobutamine

Answer 37

b1 agonist

Question 38

Dopamine

Answer 38

D1 and indirect SNS agonist

Question 39

Doxazosin

Answer 39

a1 antagonist

Question 40

Terazosin

Answer 40

a1 antagonist

Question 41

Prazosin

Answer 41

a1 antagonist

Question 42

Metoprolol

Answer 42

b1 antagonist

Question 43

Atenolol

Answer 43

b1 antagonist

Question 44

propranolol

Answer 44

b1, b2 antagonist

Question 45

labetalol

Answer 45

a1, b1, b2 antagonist

Question 46

carvedilol

Answer 46

a1, b1, b2 antagonist

Question 47

clonidine

Answer 47

a2 agonist