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Neuro Unit I > Pharmacology > Flashcards

Pharmacology Flashcards

1
Q

ANS Receptor effects

Heart

A

M2: decrease HR, decrease contractility, decrease AV node conduction
B1: increase HR/contractility

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2
Q

ANS Receptor effects

blood vessels

A

M3: vasodilation
a1: vasoconstriction
B2: vasodilation

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3
Q

ANS Receptor effects

Blood pressure

A

M3: decrease BP
a1, b1: increase BP
b2: decreare BP

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4
Q

ANS Receptor effects

Lung

A

M3: bronchoconstriction
B2: bronchodilation

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5
Q

ANS Receptor effects

Temperature Regulation

A

M3: increase sweating

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6
Q

ANS Receptor Effects

Eye

A

M3: miosis, accomodation (near vision), increase aqueous humor outflow
B1, B2: increase humor output, increase intraocular pressure

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7
Q

ANS Receptor Effects

GI/GU

A

M3: increase salivation, increase detrusor contraction (increase urine flow), increase GI motility
B2, B3: detrusor muscle relaxation
a1: close sphincter (increase continence)
B2: uterine relaxation

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8
Q

ANS Receptor Effects

CNS

A

M1: memory, cognition, meovement
a1: vigilance, focus

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9
Q

ANS Receptor Effects

NMJ

A

Nm: Muscle Contraction
B2: muscle tremors

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10
Q

Cholinergic (PNS) Agonists

A

Pilocarpine/Bethanechol (M)
Neostigmine/Pyridostigmine (indirect)
Edrophonium/Donepezil (indirect)
Organophosphate Nerve Gases (indirect)

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11
Q

Conlinergic (PNS) Antagonists

A

Atropine-Scopolamine-Benztropine (M)
Oxybutynin-Tolterodine (M)
Ipratropium-Tiotropium (M)
Atracurium-Rocuronium-Succynylcholine (Nm)

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12
Q

Adrenergic (SNS) Agonists

A 
Epinephrine (a1-a2-b1-b2)
Norepinephrine (a1-a2-b1)
Isoproterenol (b1-b2)
Albuterol (b2)
Phenylephrine (a1)
Pseudoephedrine (indirect)
Dobutamine (b1)
dopamine (d1 + indirect)
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13
Q

Adrenergic (SNS) Antagonists

A 
Doxazosin-Terazosin-Prazosin (a1)
Metoprolol-Atenolol (b1)
Propranolol (b1-b2)
labetalol-carvedilol (a1-b1-b2)
clonidine (a2 agonist)
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14
Q

Pilocarpine

A

Muscarininc Agonist

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15
Q

Bethanechol

A

Muscarinic Agonist

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16
Q

Neostigmine

A

indirect muscarinic agonist

AChE inhibitor, intermediate to long acting, reversible

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17
Q

Pyridostigmine

A

indirect muscarinic agonist

AChE inhibitor, intermediate to long acting, reversible

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18
Q

Edrophonium

A

indirect muscarinic agonist

AChE inhibitor, short acting, reversible

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19
Q

Donepezil

A

indirect muscarinic agonist

20
Q

Organophosphate nerve gases

A

indirect muscarinic agonist

21
Q

Atropine

A

Muscarinic antagonist

22
Q

Scopolamine

A

Muscarinic antagonist

23
Q

Benztropine

A

Muscarinic antagonist

increased CNS activity

24
Q

Oxybutynin

A

Muscarinic antagonist

increased CNS activity

25
Q

Tolterodine

A

Muscarinic antagonist

increased CNS activity

26
Q

Ipratropium

A

Muscarinic antagonist

27
Q

Tiotropium

A

Muscarinic antagonist

28
Q

Atracurium

A

Nm antagonist

29
Q

Rocuronium

A

Nm antagonist

30
Q

Succinylcholine

A

Nm antagonist

31
Q

Epinephrine

A

a1-a2-b1-b2 agonist

32
Q

Norepinephrine

A

a1-a2-b1 agonist

33
Q

Isoproterenol

A

b1-b2 agonist

34
Q

Albuterol

A

b2 agonist

35
Q

Phenylephrine

A

a1 agonist

36
Q

Pseudoephedrine

A

a1 indirect agonist

37
Q

Dobutamine

A

b1 agonist

38
Q

Dopamine

A

D1 and indirect SNS agonist

39
Q

Doxazosin

A

a1 antagonist

40
Q

Terazosin

A

a1 antagonist

41
Q

Prazosin

A

a1 antagonist

42
Q

Metoprolol

A

b1 antagonist

43
Q

Atenolol

A

b1 antagonist

44
Q

propranolol

A

b1, b2 antagonist

45
Q

labetalol

A

a1, b1, b2 antagonist

46
Q

carvedilol

A

a1, b1, b2 antagonist

47
Q

clonidine

A

a2 agonist

Neuro Unit I (1 decks)

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