Pharmacology

Question 1

CYP450 Inhibitors

Answer 1

Cimetidine
Ciprofloxacin 
Erythromycin
Azole antifungals 
Grape fruit juice
Isoniazid 
Ritonavir (protease inhibitors)

Question 2

CYP450 inducers

Answer 2

Carbamazepine
Phenobarbital
Phenytoin
Rifampin
Griseofulvin

Question 3

Drugs used for Parkinson’s (BALSA)

Answer 3

Bromocriptine
Amantadine
Levodopa/carbidopa
Selegiline
Antimuscarinics (Benztropine)

Question 4

DOC for stroke? Prevention of additional cerebrovascular events?

Answer 4

rtPA/tPA (DOC)

Aspirin, clopidogrel (prevention)

Question 5

DOC for trigeminal neuralgia? 2nd line?

Answer 5

Carbamazepine, oxcarbazepine (DOC)

Phenytoin, lamotrigine, gabapentin, baclofen (2nd line)

Question 6

DOC for migraine? 2nd line?

Answer 6

Sumatriptan (DOC)

Dihydroergotamine (2nd line)

Question 7

Migraine prophylaxis?

Answer 7

Beta blockers (propranolol,timolol, metoprolol)
TAC (amitriptyline, nortriptyline)
Antiepileptics (topiramate, valproate)
Intracranial Botox injections

Question 8

DOC for tension headaches?

Answer 8

NSAID’s

Question 9

DOC for cluster headaches?

Answer 9

High flow O2

Sumatriptan

Question 10

DOC cluster headache prevention? 2nd line?

Answer 10

Verapamil (DOC)

Ergotamine, lithium, prednisone (2nd line)

Question 11

Open angle glaucoma treatment?

Answer 11

Beta blocker (timolol)
Alpha adrenergic agonist (brimonidine)
Carbonic anhydrase inhibitor (acetazolamide)
Muscarinic agonist (pilocarpine, carbachol)
Prostaglandin analogues (latanoprost)

Question 12

DOC for simple/complex partial seizures?

Answer 12

Carbamazepine

Question 13

DOC for absence seizures?

Answer 13

Ethosuximide

Question 14

DOC for myoclonus seizures?

Answer 14

Valproic acid

Question 15

DOC for tonic-clonic seizures?

Answer 15

Phenytoin
Valproic acid
Carbamazepine

Question 16

DOC status epilepticus?

Answer 16

Benzodiazepines

Question 17

First line medication for bipolar disorder?

Answer 17

Lithium
Valproic acid
Carbamazepine
Atypical antipsychotics (risperidone)

Question 18

Treated for acute mania?

Answer 18

Antipsychotics (olanzapine, quetiapine, ziprasidone)

Question 19

Treatment for OCD?

Answer 19

Behavioral therapy
SSRI’s (fluoxetine, fluvoxamine)
TCA’s (clomipramine)

Question 20

Treatment for alcoholism?

Answer 20

Disulfiram
Naltrexone
Acamprosate

Question 21

Treatment for delirium tremens

Answer 21

Benzodiazepines

Question 22

First line treatment for generalized anxiety disorder?

Answer 22

Cognitive behavioral therapy
SSRI
SNRI

Question 23

2nd line treatment for general anxiety disorder?

Answer 23

Buspirone
TCA’s
Benzodiazepines

Question 24

Treatment for adjustment disorder?

Answer 24

SSRI’s

Cognitive behavioral therapy

Question 25

Treatment for panic disorder?

Answer 25

Cognitive behavioral therapy SSRI's SNRI's Benzodiazepines

Question 26

First line treatment for depression?

Answer 26

SSRI's

Question 27

Treatment for atypical depression?

Answer 27

SSRI's CBT MAOI's

Question 28

Treatment for postpartum depression?

Answer 28

SSRI's | TCA's

Question 29

Treatment for social anxiety?

Answer 29

SSRI | CBT

Question 30

Treatment for PTSD?

Answer 30

Psychotherapy | SSRI's

Question 31

Treatment for schizophrenia?

Answer 31

Traditional/atypical antipsychotics

Question 32

DOC for ventricular fibrillation?

Answer 32

Amiodarone + epinephrine/vasopressin

Question 33

Treatment of torsades de pointes? Treatment when due to congenital prolonged QT?

Answer 33

Mg2+ | Beta blocker

Question 34

Drugs that cause torsades de pointes?

Answer 34

``` Antiarrhythmics (class IA, III) Antibiotics (macrolides) Antipsychotics (haloperidol) Antidepressants (TCA's) Antiemetics (Ondansetron) ```

Question 35

Treatment of raynaud phenomenon?

Answer 35

Ca2+ channel blockers

Question 36

Treatment of congestive heart failure?

Answer 36

``` B blockers Spironolactone Ace inhibitor/ARB Diuretics (furosemide, thiazide) Digoxin ```

Question 37

Improve mortality in HF?

Answer 37

B blockers Spirinolactone Ace inhibitors/ARB

Question 38

Benefit black patients in HF?

Answer 38

Hydralazine + nitrates

Question 39

Treatment unstable angina/NSTEMI?

Answer 39

``` Ace inhibitors Aspirin B blockers Clopidogrel LMW heparin Statins ```

Question 40

Treatment for dilated cardiomyopathy?

Answer 40

Ace inhibitors/diuretics B blockers Digoxin

Question 41

DOC for Prinzmetal?

Answer 41

Ca2+ channel blockers (Diltiazem) | Nitrates

Question 42

Tx of hypertensive emergency?

Answer 42

Sodium nitroprusside

Question 43

Tx of hypertrophic cardiomyopathy?

Answer 43

Ca2+ channel blockers (verapamil, Diltiazem) B blockers ICD

Question 44

Class IA antiarrythmics? (Double quarter pounder)

Answer 44

Disopyramide Quinidine Procainamide

Question 45

Class 1B antiarrythmics? ( lettuce, tomato, mayo, pickles)

Answer 45

Lidocaine Tocainide Mexiletine Phenytoin

Question 46

Class IC antiarrythmics? (More fries please)

Answer 46

Moricizine Flecainide Propafenone

Question 47

Class II antiarrythmics?

Answer 47

B blockers ( metoprolol, propranolol, Esmolol, atenolol, timolol, Carvedilol

Question 48

Class III antiarrythmics? (AIDS)

Answer 48

Amiodarone Ibutilide Defetilide Sotalol

Question 49

Class IV antiarrythmics?

Answer 49

Diltiazem Verapamil (Ca2+ channel blockers)