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STEP1 High Yield > Pharmacology > Flashcards

Pharmacology Flashcards

1
Q

CYP450 Inhibitors

A 
Cimetidine
Ciprofloxacin 
Erythromycin
Azole antifungals 
Grape fruit juice
Isoniazid 
Ritonavir (protease inhibitors)
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2
Q

CYP450 inducers

A 
Carbamazepine
Phenobarbital
Phenytoin
Rifampin
Griseofulvin
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3
Q

Drugs used for Parkinson’s (BALSA)

A 
Bromocriptine
Amantadine
Levodopa/carbidopa
Selegiline
Antimuscarinics (Benztropine)
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4
Q

DOC for stroke? Prevention of additional cerebrovascular events?

A

rtPA/tPA (DOC)

Aspirin, clopidogrel (prevention)

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5
Q

DOC for trigeminal neuralgia? 2nd line?

A

Carbamazepine, oxcarbazepine (DOC)

Phenytoin, lamotrigine, gabapentin, baclofen (2nd line)

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6
Q

DOC for migraine? 2nd line?

A

Sumatriptan (DOC)

Dihydroergotamine (2nd line)

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7
Q

Migraine prophylaxis?

A

Beta blockers (propranolol,timolol, metoprolol)
TAC (amitriptyline, nortriptyline)
Antiepileptics (topiramate, valproate)
Intracranial Botox injections

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8
Q

DOC for tension headaches?

A

NSAID’s

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9
Q

DOC for cluster headaches?

A

High flow O2

Sumatriptan

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10
Q

DOC cluster headache prevention? 2nd line?

A

Verapamil (DOC)

Ergotamine, lithium, prednisone (2nd line)

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11
Q

Open angle glaucoma treatment?

A

Beta blocker (timolol)
Alpha adrenergic agonist (brimonidine)
Carbonic anhydrase inhibitor (acetazolamide)
Muscarinic agonist (pilocarpine, carbachol)
Prostaglandin analogues (latanoprost)

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12
Q

DOC for simple/complex partial seizures?

A

Carbamazepine

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13
Q

DOC for absence seizures?

A

Ethosuximide

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14
Q

DOC for myoclonus seizures?

A

Valproic acid

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15
Q

DOC for tonic-clonic seizures?

A

Phenytoin
Valproic acid
Carbamazepine

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16
Q

DOC status epilepticus?

A

Benzodiazepines

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17
Q

First line medication for bipolar disorder?

A

Lithium
Valproic acid
Carbamazepine
Atypical antipsychotics (risperidone)

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18
Q

Treated for acute mania?

A

Antipsychotics (olanzapine, quetiapine, ziprasidone)

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19
Q

Treatment for OCD?

A

Behavioral therapy
SSRI’s (fluoxetine, fluvoxamine)
TCA’s (clomipramine)

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20
Q

Treatment for alcoholism?

A

Disulfiram
Naltrexone
Acamprosate

21
Q

Treatment for delirium tremens

A

Benzodiazepines

22
Q

First line treatment for generalized anxiety disorder?

A

Cognitive behavioral therapy
SSRI
SNRI

23
Q

2nd line treatment for general anxiety disorder?

A

Buspirone
TCA’s
Benzodiazepines

24
Q

Treatment for adjustment disorder?

A

SSRI’s

Cognitive behavioral therapy

25
Q

Treatment for panic disorder?

A

Cognitive behavioral therapy
SSRI’s
SNRI’s
Benzodiazepines

26
Q

First line treatment for depression?

A

SSRI’s

27
Q

Treatment for atypical depression?

A

SSRI’s
CBT
MAOI’s

28
Q

Treatment for postpartum depression?

A

SSRI’s

TCA’s

29
Q

Treatment for social anxiety?

A

SSRI

CBT

30
Q

Treatment for PTSD?

A

Psychotherapy

SSRI’s

31
Q

Treatment for schizophrenia?

A

Traditional/atypical antipsychotics

32
Q

DOC for ventricular fibrillation?

A

Amiodarone + epinephrine/vasopressin

33
Q

Treatment of torsades de pointes? Treatment when due to congenital prolonged QT?

A

Mg2+

Beta blocker

34
Q

Drugs that cause torsades de pointes?

A 
Antiarrhythmics (class IA, III)
Antibiotics (macrolides)
Antipsychotics (haloperidol)
Antidepressants (TCA's)
Antiemetics (Ondansetron)
35
Q

Treatment of raynaud phenomenon?

A

Ca2+ channel blockers

36
Q

Treatment of congestive heart failure?

A 
B blockers 
Spironolactone
Ace inhibitor/ARB
Diuretics (furosemide, thiazide)
Digoxin
37
Q

Improve mortality in HF?

A

B blockers
Spirinolactone
Ace inhibitors/ARB

38
Q

Benefit black patients in HF?

A

Hydralazine + nitrates

39
Q

Treatment unstable angina/NSTEMI?

A 
Ace inhibitors 
Aspirin 
B blockers
Clopidogrel
LMW heparin
Statins
40
Q

Treatment for dilated cardiomyopathy?

A

Ace inhibitors/diuretics
B blockers
Digoxin

41
Q

DOC for Prinzmetal?

A

Ca2+ channel blockers (Diltiazem)

Nitrates

42
Q

Tx of hypertensive emergency?

A

Sodium nitroprusside

43
Q

Tx of hypertrophic cardiomyopathy?

A

Ca2+ channel blockers (verapamil, Diltiazem)
B blockers
ICD

44
Q

Class IA antiarrythmics? (Double quarter pounder)

A

Disopyramide
Quinidine
Procainamide

45
Q

Class 1B antiarrythmics? ( lettuce, tomato, mayo, pickles)

A

Lidocaine
Tocainide
Mexiletine
Phenytoin

46
Q

Class IC antiarrythmics? (More fries please)

A

Moricizine
Flecainide
Propafenone

47
Q

Class II antiarrythmics?

A

B blockers ( metoprolol, propranolol, Esmolol, atenolol, timolol, Carvedilol

48
Q

Class III antiarrythmics? (AIDS)

A

Amiodarone
Ibutilide
Defetilide
Sotalol

49
Q

Class IV antiarrythmics?

A

Diltiazem
Verapamil
(Ca2+ channel blockers)

STEP1 High Yield (2 decks)

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