Pharmacology Flashcards

1
Q

study of the harmful effects of chemicals on living things

A

toxicology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

area of pharmacology that refers to the use of specific drugs to prevent, treat or diagnose disease

A

pharmacotherapeutics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

analysis of what the drug does to the body, including the
mechanism by which the drug exerts its effect ands its
beneficial or adverse effects atthe cellular or organ level

A

pharmacodynamics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

analysis of what the body does tothe drug.
how body deals with drug; how it is absorbed, distributed,
metabolized & excreted

A

pharmacokinetics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Directs therapeutics according to person’s genotype and examine unexpected reactions to drugs

A

Pharmacogenetics/Pharmacogenomics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

effects of drugs by large populations and examines all factors

A

pharmacoepidemiology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

area of pharmacology looking at cost:benefit

A

pharmacoeconomics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q
  • lol
A

beta blockers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

andr

A

androgens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

setron

A

serotonin receptor antagonists

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

-arabine

A

selected antineoplastics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

azepam

A

antianxiety agents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

imab

A

monoclonal antibody

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

cort

A

cortisone derivative

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

curium

A

neuromuscular blocking agent

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

bactam

A

beta lactamase inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

bamate

A

tranquilizers, antiepileptics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

barb

A

barbituric acid derivatives

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

butazone

A

anti inflammatory analgesics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

caine

A

local anesthetics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

cef or ceph

A

cephalosporins

22
Q

cillin

A

penicillin

23
Q

conazole

A

anti fungals

24
Q

cycline

A

tetracycline antibiotics

25
pharmacokinetics- ADME=?
absorption distribution metabolism elimination
26
Percentage of drug that reach the general bloodstream
bioavailability
27
After absorption from gastrointestinal tract, the drug is first carried through the liver where it might be metabolized / destroyed prior to reaching the general circulation and the sites of action
first pass effect
28
Defines the most common methods of drugadministration that do not use the GI tract
parenteral
29
virchow triad?
1. stasis of bed flow: bedrest, immobility 2. endothelia injury: trauma 3. hypercoaguability of blood: oncologic diseases
30
how chemicals affect living tissue
pharmacology
31
drug classes
A group of drugs that have certain things in common and work in a similar way 

32
specific biochemical interaction through which a drug substance 
produces its pharmacological effect. Includes mention of specific molecular targets to which the drug binds such as an enzyme or receptor. 

mechanism of action
33
a secondary, typically undesirable effect of a drug or medical treatment 

side effects
34
how body deals with drug; how it is absorbed, distributed, 
metabolized and excreted
pharmacokinetics
35
analysis of what the drug does in the body, including mechanism 
by which drug exerts its effect and its beneficial or adverse effects at cellular or organ level 

pharmacodynamics
36
schedule I to schedule V
a. Schedule I – highest potential for abuse 
 b. Schedule II – high potential for abuse and addiction 
 c. Schedule III – less potential for abuse (mild to moderate) 
 d. Schedule IV – low possibility of abuse 
 e. Schedule V – lowest abuse potential 

37
Discovered and developed by a pharmaceutical company. | Have patent for certain amount of years and no one can make it until patent is over.
brand/trade name
38
what the structure is
chemical
39
same active ingredients as brand name, but can only be made after the patent has ended 

generic
40
- lol
beta blockers
41
- azepam
antianxiety agents
42
-curium
neuromuscular blocking agents
43
-cort
cortisone derivatives
44
Mimic effects of neurotransmitters naturally found in human brain. Aids in production of enhancement of action. Stimulates and action. Works at time of relaxation of muscles. Imitates action of neurotransmitters.
agonist
45
first acts like neurotransmitter, binding directly to receptor site – direct bind allows recipient to experience effects of drug as if they were released directly into brain. Ex. : dopamine, apomorphine, and nicotine 

direct binding
46
enhance neurotransmitter actions by stimulating neurotransmitters release, increasing emissions. Example: cocaine 

indirect binding
47
Block brains neurotransmitters. Opposes action of agonist and blocks reception. Sit idle and do nothing while agonist are working. Response blocked by working against drug. Works during the phase of muscle contraction. Manage status- quo of receptors by staying away from altering its activity although the might help in getting receptors bound. Action of neurotransmitter is obstructed.
antagonist
48
take up space present on receptors otherwise occupied by neurotransmitters. End result is that neurotransmitters themselves are blocked from binding to receptors. Example: atropine 

direct acting- antagonist
49
inhibiting release or production of neurotransmitter are known as indirect-acting antagonist. Example: reserpine 

indirect acting
50
Describe the general concept of the MOA of analgesics
Depress thalamus and interfere with transmission of pain impulses. In addition, brains interpretation of pain may be altered with the use of these drugs.