Pharmacology Flashcards

1
Q

study of the harmful effects of chemicals on living things

A

toxicology

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2
Q

area of pharmacology that refers to the use of specific drugs to prevent, treat or diagnose disease

A

pharmacotherapeutics

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3
Q

analysis of what the drug does to the body, including the
mechanism by which the drug exerts its effect ands its
beneficial or adverse effects atthe cellular or organ level

A

pharmacodynamics

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4
Q

analysis of what the body does tothe drug.
how body deals with drug; how it is absorbed, distributed,
metabolized & excreted

A

pharmacokinetics

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5
Q

Directs therapeutics according to person’s genotype and examine unexpected reactions to drugs

A

Pharmacogenetics/Pharmacogenomics

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6
Q

effects of drugs by large populations and examines all factors

A

pharmacoepidemiology

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7
Q

area of pharmacology looking at cost:benefit

A

pharmacoeconomics

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8
Q
  • lol
A

beta blockers

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9
Q

andr

A

androgens

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10
Q

setron

A

serotonin receptor antagonists

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11
Q

-arabine

A

selected antineoplastics

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12
Q

azepam

A

antianxiety agents

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13
Q

imab

A

monoclonal antibody

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14
Q

cort

A

cortisone derivative

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15
Q

curium

A

neuromuscular blocking agent

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16
Q

bactam

A

beta lactamase inhibitor

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17
Q

bamate

A

tranquilizers, antiepileptics

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18
Q

barb

A

barbituric acid derivatives

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19
Q

butazone

A

anti inflammatory analgesics

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20
Q

caine

A

local anesthetics

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21
Q

cef or ceph

A

cephalosporins

22
Q

cillin

A

penicillin

23
Q

conazole

A

anti fungals

24
Q

cycline

A

tetracycline antibiotics

25
Q

pharmacokinetics- ADME=?

A

absorption
distribution
metabolism
elimination

26
Q

Percentage of drug that reach the general bloodstream

A

bioavailability

27
Q

After absorption from gastrointestinal
tract, the drug is first carried through the liver where it might be metabolized / destroyed prior to reaching the general
circulation and the sites of action

A

first pass effect

28
Q

Defines the most common methods of drugadministration that do not use the GI tract

A

parenteral

29
Q

virchow triad?

A
  1. stasis of bed flow: bedrest, immobility
  2. endothelia injury: trauma
  3. hypercoaguability of blood: oncologic diseases
30
Q

how chemicals affect living tissue

A

pharmacology

31
Q

drug classes

A

A group of drugs that have certain things in common and work in a similar way 


32
Q

specific biochemical interaction through which a drug substance 
produces its pharmacological effect.
Includes mention of specific molecular targets to which the drug binds such as an enzyme or receptor. 


A

mechanism of action

33
Q

a secondary, typically undesirable effect of a drug or medical treatment 


A

side effects

34
Q

how body deals with drug; how it is absorbed, distributed, 
metabolized and excreted

A

pharmacokinetics

35
Q

analysis of what the drug does in the body, including mechanism 
by which drug exerts its effect and its beneficial or adverse effects at cellular or organ level 


A

pharmacodynamics

36
Q

schedule I to schedule V

A

a. Schedule I – highest potential for abuse 

b. Schedule II – high potential for abuse and addiction 

c. Schedule III – less potential for abuse (mild to moderate) 

d. Schedule IV – low possibility of abuse 

e. Schedule V – lowest abuse potential 


37
Q

Discovered and developed by a pharmaceutical company.

Have patent for certain amount of years and no one can make it until patent is over.

A

brand/trade name

38
Q

what the structure is

A

chemical

39
Q

same active ingredients as brand name, but can only be made after the patent has ended 


A

generic

40
Q
  • lol
A

beta blockers

41
Q
  • azepam
A

antianxiety agents

42
Q

-curium

A

neuromuscular blocking agents

43
Q

-cort

A

cortisone derivatives

44
Q

Mimic effects of neurotransmitters naturally found in human brain.
Aids in production of enhancement of action.
Stimulates and action.
Works at time of relaxation of muscles.
Imitates action of neurotransmitters.

A

agonist

45
Q

first acts like neurotransmitter, binding directly to receptor site – direct bind allows recipient to experience effects of drug as if they were released directly into brain.
Ex. : dopamine, apomorphine, and nicotine 


A

direct binding

46
Q

enhance neurotransmitter actions by stimulating neurotransmitters release, increasing emissions.
Example: cocaine 


A

indirect binding

47
Q

Block brains neurotransmitters.
Opposes action of agonist and blocks reception. Sit idle and do nothing while agonist are working. Response blocked by working against drug. Works during the phase of muscle contraction. Manage status- quo of receptors by staying away from altering its activity although the might help in getting receptors bound. Action of neurotransmitter is obstructed.

A

antagonist

48
Q

take up space present on receptors otherwise occupied by neurotransmitters. End result is that neurotransmitters themselves are blocked from binding to receptors.
Example: atropine 


A

direct acting- antagonist

49
Q

inhibiting release or production of neurotransmitter are known as indirect-acting antagonist.
Example: reserpine 


A

indirect acting

50
Q

Describe the general concept of the MOA of analgesics

A

Depress thalamus and interfere with transmission of pain impulses. In addition, brains interpretation of pain may be altered with the use of these drugs.