Pharmacology

Question 1

List 5 hormonal treatments for dysfunctional uterine bleeding

Answer 1

1. COCP/HRT (not very successful)
2. Progestogens - continual treatment (stops periods)
3. Danazole - side effect: androgen if properties
4. Mirena IUS
5. GnRH analogue (full on, no pulsatility - switch off HPO axis)

Question 2

List 3 surgical options to treat dysfunctional uterine bleeding

Answer 2

1. Hysterectomy (abdominal/vaginal/laparoscopic)
2. Endometrial resection
3. Endometrial ablation (electrocautery/laser/thermal/microwave)

Question 3

List 4 non-hormonal management methods for dysfunctional uterine bleeding

Answer 3

1. Ferrous sulphate
2. NSAIDs
3. Tranexamic acid
4. Ethamsylate