Pharmacology

Question 1

Why doesn’t LA work in infection?

Answer 1

• With infection/abscess, pH drops and the environment becomes acidic
• Local anesthetic is very pH sensitive and diffusion into the nerve fibres will be slow

Question 2

Amt of epinephrine in 1.8mL of local anesthetic

Answer 2

1: 100k = 0.018mg
1: 50k = 0.036mg