Pharmacology Flashcards by Angie Cummins

B1 receptors act on

heart cells

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B2 receptors act on

smooth muscle (bronchial cells)

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A1 receptors act on

organs

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Anti anginals do their job 2 ways

decrease O2 demand and increase O2 supply

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What 2 types of drugs (that are used for anti anginal) do their job by way of decreasing O2 demand

BB, nitrates

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what 2 types of drugs (that are used for anti anginal) do their job by way of increasing O2 supply

CCB, anti coags

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4 main types of drugs used for CHF

diuretics, sympathos, ACE inhibitors, BB

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a sympathetic antagonist works how

prevents neurotransmitters (norep and ep) from binding

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_______olol

beta blockers

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BB are used for what

angina
arrythmia
post MI

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The 2 selective BB

AM (atenolol and metoprolol)

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What does selective mean

only works with B1 (heart) receptors

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the 2 non selective BB

N…..olol, P…..olol

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Betablockers work how

decrease HR, decrease O2 demand

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What to use for intensity or limiting factor with pts on BBs

nothing related to HR

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How do nitrates work

vasodilate and decrease workload of heart

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Nitrates especially work on the

venous side- preload

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PT imiplications for nitrates

report ANY differences in their angina and watch thermo modalities as increased venous pooling can occur

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Isodril is a

nitrate

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Nitro_____

Nitrate (anti anginal)

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Nifedipine

CCB (selective)

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How do CCB work

dilates coronary arteries blocking Ca and slows conduction

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CCB are used for what 2 main things

anti arrythmic, anti anginal

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CCB PT implications

monitor for HR, diziness or any changes

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Furosemide

another name for Lasix (Diuretic)

Diuretics are used for what 2 main things

CHF, HTN

spironolactone

name of a diuretic

Thiazides

diuretics

PT implications diuretics

K wasting ones (lose K = arrythmias)

Vasodilators are used for

CHF HTN

These type of vasodilators act directly on the local arteries (local controls)

non adrenergic

Hydralazine

non adrenergic vasodilator

These vasodilators work by reducing peripheral resistance

alpha adrenergic

______zosin or | _____press

alpha adrenergic vasodilators

issue with alpha adrenergic vasodilators

can cause ortho hypotension

____zosin ____press can cause

ortho hypo tension

_______opril

ACE inhibitors (vasodilators)

side effect of _____opril

dry cough (only with inhibitors)

Losartan

Angiotenson receptor blocker

issue with centrally acting vasodilators

can cause sexual dysfunction

Dig_______

cardiac glycosides

Cardiac glycosides are used for

CHF, arrythmias

Issues with Dig_______

can quickly cause toxicity, can cause ST segment depression like a subendo MI

What should a pt do 10-14 days prior to ex testing if they take Dig_____

stop

Dig____ can also cause

visual issues or arrythmia

Anti-arrythmics are (category)

Na channel blockers

_______amide

anti arythmic (Na channel blocker)

Quin______

anti arythmic

any drug used to tx arrythmia can cause

arrythmia

cholenergic input causes

bronchoconstriction

cyclic AMP acts via

2nd messenger sx

sympatho drugs are beta 2

agonists

albuterol (_____erol)

sympatho

metaproterenol

also a sympatho beta 2 agonist

beta 2 agnonists mimic

sns

SNS causes broncho___

dilation

Phentolamine

an alpha antagonist sympatho

anticholenergics do what

broncho dilate

parasympathos are

anticholenergic bronchodilators

Methylxanthines do

bronchodilation

______phyline

are methylxanthines = bronchodilation

Theo____

methylxathine

issue with theodur

toxic levels are very close to therapeutic

side effects or toxicity of theodur

nausea, irritability, confusion working towards seizures and arrythmia

_____asone

corticosteroids (anti inflamms)

prohpolactic anti inflamm won't prevent bronchoconstriction during asthma attack) (this is a prevention drug, not an acute tx drug)

Cromolyn

___leukast | ___leu___

anti-inflamm/leukotrienes used with children

leukitrienes main plus

no side effects

These Thin secretions by breaking disulfide bonds of mucus

mucolytics (smell like rotten eggs)

metaproterenol

beta 2 agonist (sympatho) broncho dilator

albuterol is a ____ acting ____

fast/short acting selective sympatho drug

Isoproterenol is a _____, _______

non selective sympatho

Catapress

alpha adrenergic vasodilator

Terazosin | Doxazosin

alpha adrenergic vasodil

Linsinopril and Catopril are

ACE inhitibing Vasodilators

How do ACE inhibitors work

1. Reduces pressure by inhibiting the conversion of angiotensin I to angio II 2. Indirectly leads to decreased aldosterone secretion

If a pt has CHF with afib, they are prob on a

Dig (cardiac glycosolide)

Quinidex or Quinidine

antiarythmic (Na blocker)

Which of the sympatho B2 agonists are selective

albuterol | metaproterenol

which B2 agonist is not selective

isoproterenol

main K wasting diuretic

lasix

spirilactone diuretic is K

sparing