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GI II > Pharmacology > Flashcards

Pharmacology Flashcards

1
Q

Dexlansoprazole

A

Proton Pump Inhibitor

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2
Q

Esmeprazole (Nexium)

A

PPI

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3
Q

Lansoprazole (Prevacid)

A

PPI

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4
Q

Omeprazole (Prilosec)

A

PPI - may inhibt warfarin metabolism

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5
Q

Pantoprazole (Protonix)

A

PPI

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6
Q

Rabeprazole

A

PPI

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7
Q

Cimetidine (Tagamet)

A

H2 Receptor Antagonist

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8
Q

Famotidine (Pepcid)

A

H2RA

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9
Q

Nizatidine

A

H2RA

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10
Q

Ranitidine (Zantac)

A

H2RA

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11
Q

Sodium bicarbonate (baking soda, Alka Seltzer)

A

Antacids

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12
Q

Calcium carbonate (Tums)

A

Antacids

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13
Q

Magnesium hydroxide/Aluminum hydroxide (Mylanta, Maalox)

A

Antacids

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14
Q

Bismuth subcitrate

A

Mucosal Protection

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15
Q

Bismuth subsalicylate

A

Mucosal Protection (Pepto-Bismol)

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16
Q

Misoprostol

A

Mucosal Protection - prostaglandin analog

not well tolerated, not in pregnancy

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17
Q

Sucralfate (Carafate)

A

Mucosal Protection

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18
Q

Amoxicillian

A

Antibiotic for H. pylori

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19
Q

Clarithromycin

A

Antibiotic for H. pylori

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20
Q

Metronidazole

A

Antibiotic for H. pylori

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21
Q

Tetracycline

A

Antibiotic for H. pylori

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22
Q

5-aminosalicylic acid

A

IBD - first line for mild/moderate UC

ADR: nephrotox, lupus like, pancreatitis, hepatotox

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23
Q

Apriso, Asacol, Lialda, Pentasa

A

Delayed/extended release 5-aminosalicylic acid (IBD)

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24
Q

Sulfasalazine, balsalazide, slsalazine

A

Prodrug - 5-aminosalicylic acid (IBD)

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25
Q

Rowasa, Canasa

A

Rectal formulations - 5-aminosalicylic acid (IBD)

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26
Q

Prednisone

A

Corticosteroid (IBD) inhibits inflammatory cytokines

moderate to severe IBD

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27
Q

Budesonide

A

Corticosteroid (IBD)

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28
Q

Hydrocortisone

A

Corticosteroid (IBD)

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29
Q

Azathioprine

A

Immunosuppressants (IBD) purine analog

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30
Q

Mercaptopurine (6-MP)

A

Immunosuppressants (IBD) purine analog

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31
Q

Methotrexate(MTX)

A

Immunosuppressants (IBD) - inhibits DHF reductase/ macrophages
maintain remission of CD
ADR: bone marrow, megaloblastic anemia, alopecia

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32
Q

Cyclosporine

A

Immunosuppressants (IBD)

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33
Q

Infliximab

A

Anti-TNF alpha antibody (IBD) inhibits calcineurin
TNF key pro inflammatory cytokine
severe CD
severe infections, antibodies to antibody, serum sickness

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34
Q

Adalimumab

A

Anti-TNF alpha antibody (IBD)

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35
Q

Certolizumab pegol

A

Anti-TNF alpha antibody (IBD)

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36
Q

Natalizumab

A

alpha4-integrin Monoclonal Antibody (IBD)

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37
Q

Metronidazole

A

Antibiotics (IBD)

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38
Q

Ciprofloxacin

A

Antibiotics (IBD)

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39
Q

Lubiprostone

A

Laxatives (IBS)

40
Q

psyllium, bran

A

Bulk forming laxatives (IBS)

41
Q

Loperamide (Imodium)

A

Anti-Diarrheal Agents (IBS)

42
Q

Diphenoxylate (Lomotil)

A

Anti-Diarrheal Agents (IBS)

43
Q

Tegaserod - withdrawn

A

Prokinetic Agent (IBS)

44
Q

Alosetron

A

5HT3 Antagonist (IBS)

45
Q

Dicyclomine

A

Antispasmodic Agents (IBS) anticholinergics

46
Q

Hyoscyamine sulfate

A

Antispasmodic Agents (IBS) anticholinergics

47
Q

Amytriptyline

A

Antidepressants (IBS)

48
Q

Peginterferon alfa

A

HBV/HBC drug - inhibits viral penetration/replication
ADR flu like illness, neurotoxic (chronic use)
CI hepatic decomposition and psychiatric disease

49
Q

Adefovir

A

HBV drug - Nucleoside Analog
inhibits DNA polymerase, PO
ADR: HA diarrhea, ab pain, renal probs
not first line

50
Q

Entecavir

A

HBV drug - NA
inhibit DNA polymerase
first line

51
Q

Lamivudine

A

HBV drug - Nuleoside analog
inhibit DNA polymerase
HIV, not first line

52
Q

Telbivudine

A

HBV drug - NA
inhibits DNA polymerase
no use with interferon alfa
not first line

53
Q

Tenofovir

A

HBV drug - NA
inhibits DNA polymerase
ADR: decrease bone density
first line

54
Q

Ribavirin

A

HCV drug
inhibits RNA initiation/elongation
ADR: hemolytic anemia, teratogenic, oncogenic, gonadotoxic

55
Q

Simeprevir

A

HCV drug

inhibits protease

56
Q

Sofosbuvir

A

HCV drug

inhibits RNA polymerase

57
Q

Boceprevir

A

HCV drug - Protease Inhibitors

58
Q

Ondansetron (Zofran)

A

5-HT3 antiemetic

59
Q

Granisetron

A

5-HT3 antiemetic

60
Q

Dolasetron

A

5-HT3 antiemetic

61
Q

Palonosetron

A

5-HT3 antiemetic

62
Q

Metoclopramide

A

Substituted Benzamide - D2 receptor antagonist - antiemetic

63
Q

Chlorpromazine

A

Phenothiazines - D2 Receptor Antagonists - antiemetic

64
Q

Prochlorperazine

A

Phenothiazines - D2 Receptor Antagonists - antiemetic

65
Q

Thiethylperazine

A

Phenothiazines - D2 Receptor Antagonists - antiemetic

66
Q

Triflupromazine

A

Phenothiazines - D2 Receptor Antagonists - antiemetic

67
Q

Cyclizine

A

Antihistamine - antiemetics

68
Q

Dimenhydrinate (Dramamine)

A

Antihistamine - antiemetics

69
Q

Diphenhydramine (Benadryl)

A

Antihistamine - antiemetics

70
Q

Hydroxyzine

A

Antihistamine - antiemetics

71
Q

Meclizine

A

Antihistamine - antiemetics

72
Q

Promethazine

A

Antihistamine - antiemetics

73
Q

Scopalamine

A

Antimuscarinics - antiemetics

74
Q

Dronabinol

A

Cannabinoids - antiemetics

75
Q

Aprepitant

A

Neurokinin Receptor Antagonist - antiemetic

76
Q

Fosaprepitant

A

Neurokinin Receptor Antagonist - antiemetic

77
Q

Dexamethasone

A

Corticosteroids - antiemetics

78
Q

Methylprednisolone

A

Corticosteroids - antiemetics

79
Q

Lorazepam

A

Benzodiazepines - antiemetics

80
Q

Alprazolam

A

Benzodiazepines - antiemetics

81
Q

Diazepam

A

Benzodiazepines - antiemetics

82
Q

Loperamide (Imodium)

A

Opioids - Antidiarrheal agents

83
Q

Diphenoxylate (Lomotil)

A

Opioids - Antidiarrheal agents

84
Q

Difenoxin

A

Opiods - Antidiarrheal agents

85
Q

Paregoric (camphorated opium tincture, morphine)

A

Opiods - Antidiarrheal agents

86
Q

Octreotide acetate

A

Somatostatin analog - Antidiarrheal agents

87
Q

Bismuth subsalicylate (Pepto-Bismol)

A

Mucosal Protective Agents - Antidiarrheal agents

88
Q

Saline Laxatives

A

Osmotic Laxitive

89
Q

Nondigestible sugars and alcohols

A

Osmotic laxitive

90
Q

Polyethylene Glycol-Electrolytes

A

Osmotic laxitive

91
Q

Stimulant Laxitives

A

Laxitives

92
Q

Stool Softeners

A

Laxitives

93
Q

Metoclopramide

A

Prokinetic Laxitive

94
Q

Domperidone

A

Prokinetic Laxitive

95
Q

Erythromycin

A

Prokinetic Laxitive

GI II (1 decks)

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