Pharmacology

Question 1

You step on a nail and it penetrates through your sweaty gym shoe into your foot. What’s the likely microbe to infect your foot?

Answer 1

Psedomonas auriginosa

Question 2

What are the three most effective control to reduce a potential hazard according to the hierarchy of hazard control? Provide examples

Answer 2

1) Elimination
2) Substitution
3) Engineering controls

For drugs the first two are strait forward. The third could involve computer alerts that prevent you from moving forward if a potential problem exisits.

Question 3

A physician prescribes too little antibiotic and because it’s not at the MIC the patient starts to going down hill. A text alert pages the physician with this information and they rush to the patents bedside to correct the error. The patient almost dies as a result. Grief stricken the physician takes their own life. Which issues related to Saftey took place?

A) Swiss cheese model of accident causation
B) second victim
C) predictive Saftey method
D) PPE
E) A and C
D) B and C

Answer 3

D the text message with a real time alert was predictive in nature, and the physician who took their own life was an example of a second victim.

Question 4

1) a nurse spills some saline causing a patient to fall and break their hip, after which the nurse is blamed, shamed, and retrained.
2) a new drug comes to market and the hospital decides to make a protocol to prevent its misuse, as its a potentially dangerous drug
3) a physician is sent text alerts anytime one of their patients start to seriously decline

The correct order of these Saftey methods is
A) 123
B) 231
C) 213
D) 132

Answer 4

A 123

Question 5

Which of the following is NOT a culprit of drug induced CNS disease?

A) starting dose for a new drug is too high
B) change in patients kidney function
C) pump malfunction
D) method of delivery: IV, IM, p/o

Answer 5

D

Question 6

List all of the check point which maybe undermined by the Swiss cheese model of accident causation

Answer 6

Prescriber, pharmacy, computer, nurse, technology, care giver

Question 7

Your on the 27th hour of a 32hr shift in a rural hospital with computer software issues. You feel that you properly input the patients ideal weight into the computer to dose for acyclovir, but the automatic conversion turns your input of kg to lbs and the dosing is off. If something adverse happens to the patient what’s the most appropriate actions to be taken?

A) fire the doctor
B) fix the computer system
C) evaluated all the barriers to proper care and proactively change your hospital protocols
D) suspend the physician, and then retrain them

Answer 7

C
This is an example of a job made more difficult by systems that don’t work and thus systems should be addressed. If the doctor were drunk or something more negligent they should be disciplined.

Question 8

What’s the bow tie model of Saftey?

Answer 8

Hazards come in various types and can break through proactive controls leading to an adverse incident. On the other side you need reactive controls in place to deal with the incident leading to various good outcomes.

Question 9

Wilton’s disease is characterized by an increase in the body of what metal?

Answer 9

Cu

Question 10

RLS may be the result of what type of deficiency ?

Answer 10

Iron

Question 11

Huntingtons disease results in dementia and what movement disorder? What’s the reason for this movement disorder and how does it relate to the treatment of the disease?

Answer 11

Chorea- which is an over activity of dopaminergic

Treatment is with a dopamine receptor antagonist (decrease dopamine activity) haloperidol