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SNS, PSN: Pharmacology, Physiology, Pathophys > Pharmacology > Flashcards

Pharmacology Flashcards

1
Q

Pilocarpine

A
  • Cholinergic
  • Agonist
  • Muscarinic
  • AchE sensitive
    treats xerostomia (dry mouth) in cemo and sjogren’s pt.
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2
Q

Bethanechol

A
  • Cholinergic
  • Agonist
  • Muscarinic
  • Not hydrolysed by AchE (longer lasting)
  • for postoperative or postpartum urinary retention
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3
Q

Neostigmine

A
  • Cholinergic
  • Agonist
  • low doses Inhibits AchE, high dose blocks Achr
  • Treats myasthenia Gravis
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4
Q

Pyridostigmine

A
  • Cholinergic
  • Agonist
  • low doses Inhibits AchE, high dose blocks Achr
  • Treats myasthenia Gravis, nerve gas
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5
Q

Edrophonium

A
  • Cholinergic
  • Agonist
  • Inhibits AchE
  • Diagnose myasthenia gravis
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6
Q

Donepezil

A
  • Cholinergic
  • Agonist
  • Inhibits AchE
  • used in alzheimer’s
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7
Q

Organophosphate Nerve Gases

A
  • Cholinergic
  • Agonist
  • Inhibits AchE
  • causes death by asphyxiation
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8
Q

Atropine

A
  • Cholinergic
  • Antagonist
  • Muscarinic competitive antagonist
  • increases firing of SA Node.
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9
Q

Scopolamine

A
  • Cholinergic
  • Antagonist
  • Muscarinic competitive antagonist
  • for motion sickness; Mostly M1 receptor
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10
Q

Oxybutynin

A
  • Cholinergic
  • antagonist
  • Muscarinic competitive antagonist
  • for overactive blader; M1, M2, M3 receptor
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11
Q

Tolterodine

A
  • Cholinergic
  • antagonist
  • Muscarinic competitive antagonist
  • for overactive blader; M1, M2, M3 receptor
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12
Q

Rocuronium

A
  • Cholinergic
  • Antagonist
  • competitive block at nicotinic receptor at the neuromuscular junction
  • for use with anesthetic in surgery. also lethal injection.
  • antagonised by AchEI’s
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13
Q

Atracurium

A
  • Cholinergic
  • Antagonist
  • competitive block at nicotinic receptor at the neuromuscular junction
  • for use with anesthetic in surgery. also lethal injection.
  • antagonised by AchEI’s
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14
Q

succinylcholine

A

Cholinergic

  • antagonist
  • depolarizes Ach nicotinic receptor at MEP but is not hydrolized, desensitizes neuron
  • used as muscle relaxer in surgery.
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15
Q

tubocurarine

A

-cholinergic
Antagonist
- Blocks nicotinic neuromuscular MEP
-used for tobacco withdrawal

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16
Q

Epinepherine

A

Adrenergic

  • agonist
  • A1, B1, B2
  • from adrenal medulla, used in asthma and cardiac failure
17
Q

Norepinephrine

A

Adrenergic

  • agonist
  • A1, B1, (A2)
  • used in cases of neurogenic shock and vasodilatory shock, can be used as a vasopressor in critical hypotension
18
Q

Isoproterenol

A

Adrenergic

  • agonist
  • B1, B2
  • uses are asthma and transient heart block
19
Q

Albuterol

A

Adrenergic

  • agonist
  • B2
  • asthma
20
Q

Clonidine

A

Adrenergic

  • agonist
  • A2
  • Hypertensive agent, crosses bb to hypothalamus A2 receptors to lower BP. also used to treat stress sleep and anxiety disorders.
21
Q

Phenylephrine

A

Adrinergic

  • agonist
  • A1
  • treats nasal congestion and can be helpful with hypotensive shock
22
Q

Pseudophedrine

A

adrenergic

  • agonist
  • indirectly stimulates A and B receptors to release NorEpi
  • used for congestion
23
Q

Dobutamine

A

Adrenergic

  • Agonist
  • B1
  • used for Cardiac decompensation, decreased contractility from organic or surgical cause
24
Q

Dopamine

A

Adrenergic

  • agonist
  • D1 indirect- releases norepi and acts on B receptors in the heart
  • used for hemodynamic imbalance, MI, shock, ect
25
Q

Prazosin

A

Adrenergic

  • Antagonist
  • A1
  • used for hypertension, BPH symptoms, severe heart failure
26
Q

Doxazosin

A

Adrenergic

  • Antagonist
  • A1
  • used for hypertension, BPH symptoms, severe heart failure
27
Q

Terazosin

A

Adrenergic

  • Antagonist
  • A1
  • BPH symptoms, some BP lowering
28
Q

phentolamine

A

adrenergic

  • antagonist
  • A1, A2
  • helps Diagnose pheochromocytoma or hypertensive crisis
29
Q

phenoxybenzamine

A

adrenergic

  • antagonist
  • A1, A2
  • helps sweating with a pheochromocytoma or essential hypertension
30
Q

Metoprolol and Atenolol

A

Adrenergic
-antagonist
-B1
Atenolol (very lipid soluble) Angina and hypertension
Metoprolol- Acute MI, heart failure, hypertension, angina

31
Q

propranolol

A

Adrenergic

  • antagonist
  • B1, B2
  • heart and migraines
32
Q

Labetalol

A

Adrenergic

  • antagonist
  • B1, B2, A1
  • Hypertension, angina, preeclampsia
33
Q

Carvadilol

A

Adrenergic

  • antagonist
  • B1, B2, A1
  • Hypertension and NYHA class II or III heart failure

SNS, PSN: Pharmacology, Physiology, Pathophys (1 decks)

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