pharmacology Flashcards
chlorambucil - MOA
has a cytotoxic effect on lymphocytes
3 side effects of chlorambucil
GI signs, myelosuppression, myoclonus
drugs that decrease esophageal sphincter pressure
alpha-2s, ace, mu agonist opioids
drugs that cause esophageal stricture
doxy, tetracyclines, clindamycin
what type of drug is sucralfate?
aluminum disaccharide
3 drugs sucralfate may block the absorption of?
fluoroquinolones, tetracyclines, digoxin
parasites treated by pyrantel pamoate
hooks, physaloptera
what are two uses of metronidazole?
antibiotic and immunomodulatory
most palatable form of metro?
benzoate
2 side effects of ronidazole?
reversible neurotoxicity and hepatotoxicity
what class of drugs are metro and ronidazole?
nitroimidazoles
steroid of choice with heart disease?
dexamethasone
MOA of cyclosporine in IBD?
suppresses T lymphocyte-mediated inflammation
what is a type A drug reaction?
dose dependent
what is a type b drug reaction?
idiosyncratic
antifungal drugs that cause hepatotoxicity and myelosuppression (4)
griseofulvin, fluconazole, terbinafine, itraconazole
most common major side effect of chloramphenicol
myelosuppression
antimetabolite immunosuppressives (3)
azathioprine, mycophenolate, methotrexate
name 2 short-acting glucocorticoids
hydrocortisone, cortisone
