Pharmacology Flashcards
What is the mode of action of sitagliptin?
DPPIV inhibitor
What drugs worsen myasthenia gravis?
- D-penicilliamine
- Neuromuscular blocking agents e.g succinylcholine
- Aminoglycoside & fluroquinolone Abx
- Antiarrhythmics e.g procainamide
- B-blockers
Adverse effects of carbamazepine
- Ataxia
- Nystagmus
- Diplopia
What is the mode of action of docetaxel?
Binding to microtubules
Which anti-TB medication causes peripheral neuropathy?
Isoniazid
What drug is safe for hyperthyroidism in pregnancy?
Proplythiouracil
Lowest dose possible should be used due to it crossing the placenta
Which antiretroviral drugs cause hypertriglyceridaemia?
Protease inhibitors such as ritonavir and lopinavir
What drug can cause blue-grey skin pigmentation?
Minocycline
What drug can cause red urine on standing?
L-dopa
Why does metformin cause diarrhoea?
Bile salt malabsorption
What is the MOA of the progesterone only pill?
Thickens cervical mucus
What is the MOA of vancomycin?
Prevents synthesis of polymers for the bacterial cell wall
What is the most common side effect of lithium?
Hypothyroidism
Which biological agents are used in ankylosing spondylitis?
Etanercept or Adalimumab
Which anti-depressant is 1st line if a patient is on warfarin or heparin?
Mirtazapine
What is the MOA of clopidogrel?
Blocks ADP receptors
Which cardiac anti-arrhythmic shortens the QT?
Digoxin
What is the MOA of ambrisentan?
Endothelin A receptor antagonist
