Pharmacology Flashcards
Archer Review Help - Cheat Sheet, Endings, and Needs to Know about Drugs
Drug Class based on ending
-afil
Phosphodiesterase (PDE) inhibitor
- Sildenafil
- Avanafil
Drug Class based on ending
-ase
Thrombolytic
- Alteplase
- Streptokinase
Drug Class based on ending
-asone
Corticosteroid
- Fluticasone
- Betamethasone
Drug Class based on ending
-bital
Barbiturate
- Phenobarbital
- Butabarbital
Drug Class based on ending
-caine
local anesthesia
- Lidocaine
-Prilocaine
Drug Class based on ending
cef-, ceph-
cephalosporin antibiotic
- Cefdinir
- Cephalexin
Drug Class based on ending
-cillin
Penicillin antibiotic
-Amoxicillin
- Ampicillin
Drug Class based on ending
cort
corticosteroid
- Hydrocortisone
- Fludrocortisone
Drug Class based on ending
-cycline
Tetracycline antibiotic
-Doxycycline
- Minocycline
Drug Class based on ending
-dazole
anthelmintic, antibiotic
- Metronidazole
- Tinidazole
Drug Class based on ending
-dipine
Ca channel blocker
- Amlodipine
-Nifedipine
Drug Class based on ending
-done
opioid analegesic
- Hydrocodone
- Oxycodone
Drug Class based on ending
-dronate
Biphosphate, bone reabsorption inhibitor
- Alendronate
- Risperidone
Drug Class based on ending
-eprazole, -oprazole
PPI
- Esomeprazole, Omeprazole
- Lansoprazole, Pantoprazole
Drug Class based on ending
-fenac
NSAID
- Diclofenac
- Nepafenac
Drug Class based on ending
-floxacin
Quinolone antibiotic
- Ciprofloxacin
- Levofloxacin
Drug Class based on ending
-iramine
Antihistamine
- Chlorpheniramine
- Pheniramine
Drug Class based on ending
-mide
diuretic
- Furosemide
- Torsemide
Drug Class based on ending
-mycin
antibiotic
- Azithromycin
- Clindamycin
Drug Class based on ending
-nacin
Muscarinic antagonist (anticholinergic)
- Darifenacin
- Solifenacin
Drug Class based on ending
-nazole
antifungal
- Fluconazole
- Miconazole
Drug Class based on ending
-olol
Beta Blocker
- Metoprolol
-Timolol
- Propranolol
Drug Class based on ending
-olone
Corticosteroid
- Prednisolone
-Triamcinolone
Drug Class based on ending
-onide
corticosteroid
- Budesonide
- Flucinonide
Drug Class based on ending
-parin
antithrombotic, anticoagulant
-Enoxaparin
-Heparin
Drug Class based on ending
-phylline
Bronchodilator
- Aminophylline
- Theophylline
Drug Class based on ending
-pramine
Tricyclic antidepressant
-Clomipramine
-Imipramine
Drug Class based on ending
pred, pred-
corticosteroid
- Prednisolone
- Prednisone
Drug Class based on ending
-pril
ACE inhibitor
- Enalapril
-Lisinopril
Drug Class based on ending
-profen
NSAID
- ibuprofen
- Ketoprofen
Drug Class based on ending
-ridone
Atypical antipsychotic
- Paliperidone
- Risperidone
Drug Class based on ending
-sartan
Angiotensin 2 receptor antagonist
- Losartan
-Valsartan
Drug Class based on ending
-semide
Loop diuretic
- Furosemide
Drug Class based on ending
-statin
HMG-CoA reductase inhibitor
- Atorvastatin
- Simvastatin
Drug Class based on ending
sulfa-
antibiotic, anti-infective, anti-inflammatory
- Sulfacetamide
Drug Class based on ending
-terol
Beta agonist bronchodilator
- Albuterol
Drug Class based on ending
-thiazide
thiazide diuretic
- Hydrochlorothiazide
Drug Class based on ending
-tidine
H2 receptor antagonist
- Famotidine
Drug Class based on ending
-trel
female hormone - progestin
- etonogestrel
-levonorgestrel
Drug Class based on ending
-tyline
tricyclic antidepressant
- Amitripyline
Drug Class based on ending
vir, -vir
antiviral
- Ribavirin
- Tenofovir
Drug Class based on ending
-zepam
benzo
- Clonazepam
-Lorazepam
Drug Class based on ending
-zodone
antidepressant
- nefazodone
- Trazodone
Drug Class based on ending
- zolam
benzo
-Alprazolam
Drug Class based on ending
-zosin
Alpha blocker
-Doxazosin
-Terazosin
Acetaminophen antidote
Acetylcysteine and activated charcoal
Benzo antidote
Flumazenil
Cyanide poisoning antidote
Methylene blue
Digoxin toxicity antidote
Digoxin immune FAB
Ethylene poisoning antidote
Fomepizole
Heparin and enoxaparin antidote
Protamine sulfate
Warfarin antidote
Vitamin K (Phytonadione)
Iron antidote
Deferoxamine
Lead antidote
Succimer
Mg Sulfate antidote
Ca gluconate
Opioid antidote
Naloxone
Drugs to avoid with
ACE inhibitors
Potassium-sparing meds
- Hyperkalemia
Drugs to avoid with
Nitroglycerin
Erectile dysfunction meds
- profound hypotension
Drugs to avoid with Metformin
Contrast dye
-Nephrotoxicity
Drugs to avoid with
MAOI and St. John’s
Other antidepressants (2 weeks before and after)
- Serotonin syndrome
Foods to avoid with
Ca channel blockers, statins, and anticoagulants
grapefruit juice
- blocks enzyme to metabolize increases levels in the body
Foods to avoid with MAOIs
Tyramine (Charcuterie foods)
- Hypertensive Crisis
Foods to avoid with Warfarin
Excessive Vitamin K foods (need consistent amount)
- clotting and increase clot cascade
Disease to Drug Interactions
Asthma
Beta Blockers
- Bronchospasm
Disease to Drug Interactions
Chronic Liver Dzs
Warfarin
- increase sensitivity and bleeding
Disease to Drug Interactions
Congestive Heart Failure
Ca channel Blockers, NSAIDs - Na retnetion, and increase cardiac events
Steroids - Na and water retention
Disease to Drug Interactions
Epilepsy
TCAs, antimalarials, antipsychotics
- more seizures
Disease to Drug Interactions
HTN
NSAIDs
- increase BP due to Na retention
Disease to Drug Interactions
Parkinson’s
COX-2 Inhibitors
- worsening s/s
Disease to Drug Interactions
Renal Failure
NSAIDs
- Nephrotoxicity
Disease to Drug Interactions
Resp Failure
Neuroleptics
- resp depression
Nifedipine toxicity
flushing
HA
Tachycardia
Hypotension
Verapamil toxicity s/s
Bradycardia
AV Heart Block
Hypotension
Constipation
Statins toxicity
HA
GI disturbances
liver and muscle toxicity
Midazolam toxicity
increase sedation
SSRI toxicity - sertraline
serotonin syndrome
Prolonging QT Interval puts the pt at risk for
Vtach or Torsades
-EKG monitors
Grapefruit juice should not be given to what drugs
Nifedipine
Statins
Midazolam
SSRI
Verapamil
Drugs Prolonging QT Interval
Amiodarone
Nicardipine
Sotalol
Azithromycin
Erythromycin
Fluconazole
Voriconazole
Amitriptyline, Protriptyline
Escitalopram, Citalopram
Fluoxetine, Sertraline
Haldol
Quetiapine
Risperidone
Ondansetron
Lithium
Pheylephrine
Pseudophydrine
Tacrolimus
Terbutaline
Hepatotoxic Drugs
Statins
Carbamazepine
Phenytoin
Valproic acid
antifungals (-azole)
Bupropion
TCAs
Trazodone
Amoxicillin, Penicillin
Erythromycin
Amiodarone
Labetalol
Lisinopril
Losartan
Omeprazole
Acetaminophen with alcohol
Opioid Side effects
MITOSIS (pupil constriction)
OUT of it
Respiratory depression, reduced salivation
Pruritus, pneumonia
Hypotension, HA
Infrequent elimination (decrease motility)
Nausea, nervousness
Emesis
Methadone
does not cause euphoria
long half-life
- titrate slowly
(Peds on heart surgeries titrating off pain meds)
Opioid Antagonist - Antagonist
Buprenorphine
Suboxone
Buprenorphine
mild to mod pain and opioid addiction
low potenetial for abuse and less powerful
Narcan will cause
immediate withdrawal dependent on opioids
Non opioid that does not suppress inflammation
acetaminophen
NSAIDs inhibit COX 1 and 2 causing
gastric ulceration (bleeding)
vasoconstriction
renal impairment
reduced inflammation
analgesic
reduce fever
Ibuprofen side effects
GI BLEED
renal impairment
ASA best for what type of pain
joint, muscles, and head pain
arthritis
fever
stroke prevention
ASA decrease what
platelet aggregation decrease in ischemic diseases
ASA NURSING
bleeding D/C 5-7 days before surgery
Reye’s with viral infection
ASA is only used in what peds diseases
Kawasaki <16 y/o