PHARMACOLOGY

Question 1

What is Pharmacology?

Answer 1

• Study of Drugs
• Study of Biological effects of CHEMICALS
• when chemicals introduced to the body, there will be some sort of change:
• Desirable = Therapeutic Effect
• Undesirable = SE (Expected) & AE (Unexpected)

Question 2

What happens when the drugs enters the body?

Answer 2

When the drugs entered the body, there is the cell together with the receptor that receives the drugs/chemical, when the drug binds to the cell, there will be a change or effect, and this is called “PHARMACODYNAMICS”

Question 3

PHARMACODYNAMICS

Answer 3

Action of the drug

Question 4

PHARMACOKINETICS

Answer 4

Response of the drug
- e.g., Liberation, Absorption, Distribution, Metabolism, Excretion

Question 5

What are the action of the drug

Answer 5

1. Replacing a missing substance
2. Increase cellular activities
3. Depress cellular activities
4. Interfere with the growth of a foreign cell

Question 6

Drug actions maybe through:

Answer 6

• Receptor
• Enzyme
• Pumps
• Chemical Interaction
• Altering Metabolic Process

Question 7

AGONISTS

Answer 7

Drug that activates or stimulates a receptor site
- example: Epinephrine

Question 8

ANTAGONISTS

Answer 8

COMPETITIVE ANTAGONIST
- Drugs that blocks the SAME receptor site
Example: (A) Morphine and (AntaG) Naloxone
- Antidote

NON-COMPETITIVE ANTAGONIST
- drugs bind to DIFFERENT receptor sites
- action of agonist is REDUCED
Example: Cefuroxime = omeprazole

Question 9

Release of active ingredient

Answer 9

Liberation