Pharmacology Flashcards

1
Q

Which chemotherapeutic agent has been associated with cardio toxicity?

A

Doxorubicin

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2
Q

Which chemotherapeutic agent has been associated with cystitis?

A

Cyclophosphamide

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3
Q

Which chemotherapeutic agent has been associated with anaphylaxis?

A

L-asparaginase

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4
Q

Which chemotherapeutic agent can cause pancreatitis?

A

Lomustine

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5
Q

Aminoglycosides are known for their potential toxic effects to what organ?

A

Kidneys

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6
Q

Penicillins and Cephalosporins fall under what class of antimicrobials drugs?

A

Beta Lactams

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7
Q

What is the mechanism of action of penicillins and cephalosporins?

A

Inhibits formation of petidoglycan cross-links of bacterial cell wall.

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8
Q

What is the spectrum of activity of penicillins and cephalosporins?

A

Gram-Positive limited Gram-Negative Anaerobes

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9
Q

Are penecillins and cephalosporins cidal or static?

A

Cidal

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10
Q

Are penicillins and cephalosporins time or concentration dependent?

A

Time

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11
Q

Beta lactamase inhibitors can be used to extend what?

A

The anti-bacterial spectrum

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12
Q

Gentamicin and Amikacin fall under what class of antimicrobials drugs?

A

Aminoglycosides

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13
Q

What is the mechanism of action of aminoglycosides?

A

Interfere with protein synthesis

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14
Q

What is the spectrum of activity of aminoglycosides?

A

Limited Gram-Positive Gram-Negative

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15
Q

Are aminoglycosides time or concentration dependent?

A

Concentration

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16
Q
A