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Rheumatology > Pharmacology > Flashcards

Pharmacology Flashcards

1
Q

How many isoforms of AJK

A

4: JAK-1, 2,3, and TYK 2

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2
Q

Most JAK inhibition effects are mediated through this cytokine

A

IL-6

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3
Q

Broad spectrum JAK inhibitors

A

Tofacitinib and Baricitinib

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4
Q

Which 2 cytokines receptors does JAK not inhibit

A

IL-1 and TNF-alpha

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5
Q

JAK-1 selective inhibitor

A

Upadacitinib

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Rheumatology (2 decks)

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