Pharmacology Flashcards

1
Q

Collection of glands and tissues that secrete hormones into the bloodstream

A

Endocrine System

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2
Q

A chemical substance produced in the body that controls and regulates the activity of certain cells or organs.

A

Hormones

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3
Q

Three types of hormones

A

Peptide Hormones
Steroid Hormones
Amine Hormones

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4
Q

One of the principal fuels used by our body

A

Glucose

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5
Q

Cannot be given orally because of proteolytic enzymes in the GIT

A

Peptide

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6
Q

An example of a growth hormone that stimulates growth in tissue and bone

A

Sometrem (Protropin) /Somatropin (Humatrope)

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7
Q

Growth hormone inhibiting hormone [GHIH] that is contraindicated to hypersensitivity, pregnancy, lactation and with adverse effects such as GI distress, constipation/ diarrhea, flatulence, nausea, acute cholecystitis (e.g. Ocreotide [Sandostatin])

A

Somatostatin Agonists

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8
Q

An indication for diabetes insipidus, hemorrhage, and postoperative abdominal distension

A

Vasopressin, Pitressin Synthetic, Desmopressin

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9
Q

A drug that acts on the posterior pituitary gland

A

Oxytocin

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10
Q

Increases the availability of glucose

A

Glucocorticoids

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11
Q

It is used to promote lung maturation in premature infants and prevent organ transplant rejection

A

Glucocorticoids

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12
Q

A preferred drug for adrenocortical insufficiency

A

Hydrocortisone

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13
Q

Used to diagnose Cushing’s syndrome and for treatment of non-endocrine disorders

A

Dexamethasone

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14
Q

Potassium normal range

A

3.5 to 5 mL

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15
Q

Antithyroid Agents : prevent formation of thyroid hormone, inhibit conversion of T3 and T4, and increased metabolism

A

Thioamides

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16
Q

An organ that secretes digestive enzymes and releases insulin and glucagon from the Islets of Langerhans.

A

Pancreas

17
Q

A disorder of carbohydrate metabolism either from deficiency of insulin or cellular resistance to insulin’s actions

A

Diabetes Mellitus

18
Q

An anti-diabetic drug that decreases insulin resistance and glucose production in the liver

A

Thiazolidinediones

19
Q

An antidiabetic drugs that decreases glucose production by the liver and increase the tissue response to insulin.

A

Biguanides

20
Q

This is an anti-diabetic drug that increases the insulin release and reduces the glucagon release.

A

Gliptins

21
Q

A drug used to treat polycystic ovary syndrome that improves glucose tolerance, ovulation, and pregnancy rate

A

Metformin

22
Q

An antidiabetic drug that reduces rate starches that are broken down and absorbed, and also decreases postprandial rise in blood glucose

A

Alpha-glucosidase inhibitors

23
Q

Anti-diabetic drug for type II diabetes mellitus that works by opening Ca+ channels of the beta cells stimulating release of insulin

A

Sulphonylureas

24
Q

Short-acting sulphonylureas drugs

A

Gliclazide, Tolbutamide

25
Q

Long-acting sulphonylureas drugs

A

Chlorpropamide, Glibenclamide, Glipizide

26
Q

Anti-diabetic Drugs for Type 2 DM

A

Sulphonylureas, Biguanides, Alpha-Glucosidase Inhibitors, Thiazolidinediones

27
Q

It is a combined endocrine/metabolic disorder characterized by androgen excess and insulin resistance

A

PCOS (Polycystic Ovary Syndrome)

28
Q

Onset: 5-15 mins
Peak: Humalog = 30-90 mins, Novolog = 1-3 hrs
Duration: Humalog = 2-5 hrs, Novolog = 3-5 hrs

A

Rapid-Acting Insulin

29
Q

Onset: 30 mins
Peak: 2.5-5 hrs
Duration: 6-8 hrs

A

Short-Acting Insulin

30
Q

Onset: 1-2 hrs
Peak: 6-12 hrs
Duration: 18-24 hrs

A

Intermediate-Acting Insulin