Pharmacology

Question 1

Define the 3 different drug names

Answer 1

Chemical name: describes the chemical composition
Generic name: The official name listed in publications and used for prescribing
Trade (brand name): marketed name

Question 2

Define the term pharmacodynamics

Answer 2

What the drug does to the body

Question 3

Define the term pharmacokinetics

Answer 3

What the body does to the drug

Question 4

Define the term agonist

Answer 4

Binds to and activates the receptor

Question 5

Define the term antagonist

Answer 5

Binds to and deactivates receptor

Question 6

Name the 4 pharmacokinetics in the correct sequence

Answer 6

1. Absorption
2. Distribution
3. Metabolism
4. Excretion

Question 7

Describe absorption

Answer 7

The passage of medication from the site of administration into the blood

Question 8

Describe distribution

Answer 8

Movement of the drug from the blood to the bodies tissues

Question 9

Describe metabolism

Answer 9

The process of chemical medication of the drug

Question 10

Describe excretion

Answer 10

The movement of the drug from the body

Question 11

What influences absorption

Answer 11

Route of delivery
Body surface area
The ability of the medication to dissolve
Blood flow of the area of absorption

Question 12

What influences distribution

Answer 12

Cardiac function
Tissue binding
Capillary permeability
Plasma protein binding

Question 13

What influences metabolism

Answer 13

Age
Gender
Environmental factors
Disease status

Question 14

What influences excretion

Answer 14

Renal function

Question 15

State 5 ways that drugs can be excreted

Answer 15

1. Bile
2. Feces
3. Sweat
4. Breast milk
5. Expired air

Question 16

Explain Hepatic first-pass effect

Answer 16

Anything taken orally goes through the liver before it enters the systemic circulation

Question 17

Explain bioavailability

Answer 17

The proportion of the administered drug that reaches the systemic circulation intact -Drugs administered via IV is 100% bioavailability