Pharmacologic Therapy for Mood Elevation and Stabilization

Question 1

Most common drug to treat mania?

Answer 1

Lithium Carbonate

Question 2

How long will it take for symptoms to subside?

Answer 2

1-3 weeks

Question 3

What’s the mechanism of action of lithium?

Answer 3

It enhances the re-uptake of norepinephrine and serotonin which decreases levels in blood. This results I’m decreased hyperactivity!

Question 4

What are other drugs to treat mania?

Answer 4

Anticonvulsants and Ca Channel Blockers

Question 5

Anticonvulsants

Answer 5

Klonopin, Tegretaol, Depakote

Question 6

Ca Channel Blockers

Answer 6

Calan, Verapamil

Question 7

What is important to watch during lithium Tx?

Answer 7

Toxicity levels

Question 8

After what lithium level in blood do these toxicity symptoms appear?

Answer 8

>1.5 mEq/L

Question 9

For how long do pts need to take the meds after symptoms disappear to reduce risk of relapse?

Answer 9

One year

Question 10

Outpatients get a ___ week supply of meds

Answer 10

One

Question 11

Pts taking antidepressants are at increased risk for ____________ when depression begins to lift

Answer 11

Suicide

Question 12

What are EARLY lithium toxicity S&S?

Answer 12

Severe diarrhea, blurred vision, ataxia, lethargy, tinnitus

Question 13

What are some LATE lithium toxicity S&S?

Answer 13

Seizures, kidney failure

Question 14

When is the best time to check lithium levels?

Answer 14

12 hrs after the last dose

Question 15

What are some common SE of lithium?

Answer 15

Drowsiness, dizziness, HA Dry mouth, thirst N&V Fine hand tremors Hypotension, arrhythmia Polyuria, DEHYDRATION weight gain

Question 16

Client teaching for pt under Lithium tx?

Answer 16

Adequate fluid intake Do not decrease salt intake Avoid driving until meds are stabilized Carry Medic Alert ID Teach S&S of Lithium Toxicity