Pharmacokinetics - Route of Administration

Question 1

Pharmacokinetics

Answer 1

What the body does to a drug

Question 2

Pharmacodynamics

Answer 2

What the drug does to a body.

Question 3

The four Pharmacokinetic properties are:

Answer 3

Absorption, Distribution, Metabolism, Elimination

Question 4

When the drug is administered by mouth, it’s called:

Answer 4

Enteral Delivery

Question 5

When the drug is swallowed, it is called:

Answer 5

Oral Delivery

Question 6

Instead of swallowing, the drug is placed under tongue:

Answer 6

Sub lingual delivery

Question 7

Sublingual delivery has the advantage of:

Answer 7

Direct absorption of drug in Bloodstream.

Question 8

Sublingual Route is same as:

Answer 8

Buccal Route

Question 9

Coating that resists action of stomach fluids and dissolves in intestine is called:

Answer 9

Enteric coating

Question 10

Coating that determines how fast or slow the drug is released form the pill is called:

Answer 10

Extended release coating

Question 11

Administration that introduces drug directly into systemic circulation:

Answer 11

Parenteral

Question 12

The three major parenteral routes are:

Answer 12

Intravascular (IV), Intramuscular (IM), Subcutaneous (SC)

Question 13

An IM suspension in a non aqueous vehicle is called:

Answer 13

Depot Preparation

Question 14

Which Vehicle is used in Depot preparation?

Answer 14

Polyethylene Glycol

Question 15

Two examples of depot preparation are:

Answer 15

Haloperidol Sustained release, Medroxyprogesterone

Question 16

Which route of administration requires no absorption?

Answer 16

IV

Question 17

Which routes provide slow and steady release

Answer 17

Depot Preparation (IM , SC) , Transdermal patches

Question 18

Which patients are ideal for rectal administration?

Answer 18

Comatose or vomiting

Question 19

Give examples of Oral Inhalation:

Answer 19

Bronchodilator = Albutarol ; 
Corticosteroid= Fluticasone

Question 20

Give examples of Nasal Inhalation:

Answer 20

Nasal decongestants= oxymetazoline,
Anti-inflammatory corticosteroids= Mometasone furoate,
Desmopressin for treatment of diabetes insipidus, Salmon calcitonin, a peptide
hormone used in the treatment of osteoporosis. available as
a nasal spray.

Question 21

Route where drug is administered directly into the cerebrospinal fluid:

Answer 21

Intrathecal Route

Question 22

Example of intrathecal:

Answer 22

Amphotericine B for Cryptococcal meningitis

Question 23

Example of transdermal drug

Answer 23

Nitroglycerine for Angina
Scopolamine as antiemetic
Nicotine patches for Smokers who want to quit.

Question 24

The rectal route is commonly used to administer

Answer 24

Antiemetic Agents