Pharmacokinetics - Route of Administration Flashcards
Pharmacokinetics
What the body does to a drug
Pharmacodynamics
What the drug does to a body.
The four Pharmacokinetic properties are:
Absorption, Distribution, Metabolism, Elimination
When the drug is administered by mouth, it’s called:
Enteral Delivery
When the drug is swallowed, it is called:
Oral Delivery
Instead of swallowing, the drug is placed under tongue:
Sub lingual delivery
Sublingual delivery has the advantage of:
Direct absorption of drug in Bloodstream.
Sublingual Route is same as:
Buccal Route
Coating that resists action of stomach fluids and dissolves in intestine is called:
Enteric coating
Coating that determines how fast or slow the drug is released form the pill is called:
Extended release coating
Administration that introduces drug directly into systemic circulation:
Parenteral
The three major parenteral routes are:
Intravascular (IV), Intramuscular (IM), Subcutaneous (SC)
An IM suspension in a non aqueous vehicle is called:
Depot Preparation
Which Vehicle is used in Depot preparation?
Polyethylene Glycol
Two examples of depot preparation are:
Haloperidol Sustained release, Medroxyprogesterone
Which route of administration requires no absorption?
IV
Which routes provide slow and steady release
Depot Preparation (IM , SC) , Transdermal patches
Which patients are ideal for rectal administration?
Comatose or vomiting
Give examples of Oral Inhalation:
Bronchodilator = Albutarol ; Corticosteroid= Fluticasone
Give examples of Nasal Inhalation:
Nasal decongestants= oxymetazoline,
Anti-inflammatory corticosteroids= Mometasone furoate,
Desmopressin for treatment of diabetes insipidus, Salmon calcitonin, a peptide
hormone used in the treatment of osteoporosis. available as
a nasal spray.
Route where drug is administered directly into the cerebrospinal fluid:
Intrathecal Route
Example of intrathecal:
Amphotericine B for Cryptococcal meningitis
Example of transdermal drug
Nitroglycerine for Angina
Scopolamine as antiemetic
Nicotine patches for Smokers who want to quit.
The rectal route is commonly used to administer
Antiemetic Agents
