Pharmacokinetics Flashcards
1
Q
Define volume of distribution
A
The apparent volume in which a drug is dissolved in the body- Wide distribution = conc, in plasma will be low
2
Q
Vd=?
A
Amount in body/Conc.
= Dose/conc.at t=0
3
Q
What is clearance?
A
the volume of plasma cleared of a drug in unit time (removal of drug from the body) - helps determine the dose rate
4
Q
Clearance= ?
A
renal clearance +hepatic clearance
5
Q
First order kinetics
A
Rate of elimination is proportional to conc of a drug
