Pharmacodynamics of Antimicrobial Drugs Flashcards
Aminoglycosides: MOA
Protein Synthesis
Cell Membrane Leak
Cephalosporins: MOA
Cell Wall Synthesis
Fluoroquinolones: MOA
DNA Synthesis (DNA Gyrase)
Macrolides: MOA
Protein Synthesis
Penicillins: MOA
Cell Wall Synthesis
Sulfonamides: MOA
Folic Acid Synthesis
Tetracyclines: MOA
Protein Synthesis
Which 3 classes of antibiotics act on Protein Synthesis?
Tetracyclines, Macrolides, Aminoglycosides
Which 2 classes of antibiotics act on cell wall synthesis?
Cephalosporins, Penicillins
Aminoglycosides: Spectrum
G-
G+
NOT anaerobes
Cephalosporins: Spectrum
G+
G-
Fluoroquinolones: Spectrum
G+
G-
Mycoplasma
NOT anaerobes
Macrolides: spectrum
G+
Mycoplasma
Penicillins: Spectrum
G+
G-
Sulfonamides: Spectrum
G+
G-
Protozoa
Tetracyclines: Spectrum
G+
G-
Mycoplasma
Rickettsia
Chlamydia