Pharmacodynamics

Question 1

Stimulating Action

Answer 1

direct effects from a receptor agonist that stimulates the body.

Question 2

receptor

Answer 2

protein molecule in a cellular membrane that can bind to a complementary molecule

Question 3

agonist

Answer 3

chemical capable of activating a receptor to generate a therapeutic response

Question 4

partial agonist

Answer 4

only partially activates the receptor

Question 5

Depressing Action

Answer 5

direct effects from a receptor agonist that depresses the body

Question 6

Antagonizing Action

Answer 6

a drug binding to a receptor without activating it

Question 7

Stabalizing Action

Answer 7

a drug cuasing a neutral reaction, neither stimulating nor depressing the system

Question 8

Replacing Action

Answer 8

the accumulation of a substance in the system, such as a glycogen stored as carbohydrates

Question 9

Direct Constructive Chemical Reaction

Answer 9

a drug producing beneficial results

Question 10

therapeutic window

Answer 10

measures the dose required for the medication to be effective against the amount of it that would cause adverse side effects

Question 11

duration of action

Answer 11

how long the drug will be effective in the body

Question 12

affinity

Answer 12

the evolutionary relationship between a group of relative organisms

Question 13

pharmacokinetics

Answer 13

the way drugs move THROUGH the body

Question 14

pharmacology

Answer 14

the effects the drug has ON the body

Question 15

pharmacology

Answer 15

the effects the drug has ON the body

Question 16

bioavailability

Answer 16

the usable amount of the drug that reaches the body’s circulation

depends on route of administration

Question 17

bioequivalent

Answer 17

when two drugs have the same bioavailability

same chemical form, just formulated differently - GENERICS

Question 18

liberation

Answer 18

(mechanism of pharmacokinetics)

release of a drug from its pharmaceutical formulation

Question 19

absorption

Answer 19

(mechanism of pharmacokinetics)

process of a drug entering the body

Question 20

distrubution

Answer 20

(mechanism of pharmacokinetics)

the dispersion of a drug throughout the body’s fluid and tissue

Question 21

metabolism

Answer 21

(mechanism of pharmacokinetics)

transformation of a drug’s compounds into drug metabolites

Question 22

excretion

Answer 22

(mechanism of pharmacokinetics)

the elimination of a drug from the body

Question 23

first-pass effect (definition)

Answer 23

drug’s metabolism is greatly diminished before its distributed into the circulatory system

Question 24

first-pass effect happens in (2)

Answer 24

either the liver or the small intestine

Question 25

ionized

Answer 25

charged

Question 26

non-ionized

Answer 26

uncharged

Question 27

pH <7

Answer 27

acidic

Question 28

pH 7

Answer 28

neutral

Question 29

pH >7

Answer 29

alkaline

Question 30

passive diffusion

Answer 30

the inactive transport of biochemical substance without energy input

Question 31

lipid-water partition

Answer 31

form of passive diffusion

drug molecule can cross over cell membranes via lipid pathway or a water channel