Pharmacodynamics Flashcards
1
Q
Pharmacodynamics
A
-the efficacy and toxicity of a drug
2
Q
Pharmacokinetics
A
-the fate of the drug in the body
3
Q
Efficacy of a drug
A
How much you need to take and how well it work in return (what lower dosage and less drug with it working better)
4
Q
What are the 12 stages of Drug Design and Development?
A
- identify the target disease
- identify the drug target
- establish testing procedures
- find a lead compound
- structure activity relationship (SAR)
- identify a pharmacophore
- drug design - optimizing target interactions
- drug design - optimizing pharmacokinetic properties
- toxicological and safety tests
- chemical development and production
- patenting an regulatory affairs
- clinical trials
5
Q
What four specific stages of drug design and development are being focused on>
A
- find a lead compound
- structure activity relationship (SAR)
- identify a pharmacophore
- drug design - optimizing target interactions
- drug design - optimizing pharmacokinetic properties
6
Q
What are the priorities for the pharamcauetical industry?
A
-can profits from marketing a new drug outweigh the cost of developing and testing that drug?
-is the disease widespread
-does the disease affect the first world
