pharmaco dev rx Flashcards

1
Q

développement pré-clinique

A

-Molécule candidate
-Étude in vitro (cellules et animaux)
-Études toxicité aigu et chronique

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2
Q

Phase 1

A

-Humain (volontaire sain)
-Étude cinétique et toxicité court terme

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3
Q

Phase 2

A

-Patient
-Étude relation dose/effet

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4
Q

Phase 3

A

-Grosse cohorte
-Étude efficacité et innocuité + étude d’équivalence

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5
Q

Phase 5

A

Pharamco (vigilance et économie)

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