Pharmacist Only Medicines Flashcards

1
Q

Adapalene requirements of pharmacist supply

A

For severe acne, not more than 30g.

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2
Q

Adapalene instructions

A

Apply thinly OD at night to clean, dry skin. Review after 3 months. Wash off in the morning

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3
Q

Adapalene mechanism of action

A

Topical retinoid:

Inhibits keratinisation, reduces sebum production and modulates antiinflammatory response

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4
Q

Adapalene contraindications (can’t supply)

A

Pregnant or breastfeeding (and those wanting to)

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5
Q

Adapalene adverse effects

A

Redness, dryness, burning sensation at the application site

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6
Q

Adapalene advice and self-care

A

There will be an initial flare up. Should see improvement after 8 weeks

Moisturise and apply sunscreen - increased photosensitivity.

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7
Q

Brompheniramine

A

Not available by itself in NZ. Is a first-generation antihistamine. Could be sold to adults and children older than 2 for insomnia containing no more than 10 dosage units.

Is available as a pharmacy-only medicine with other cold medicines.

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8
Q

Calcipotriol requirements of pharmacist supply

A

For mild-moderate psoriasis in an adult previously diagnosed by a doctor. Not more than 30g.

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9
Q

Calcipotriol instructions

A

Apply twice daily. Wash hands thoroughly after.

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10
Q

Calcipotriol mechanism of action

A

Is a vitamin D analogue. It is an antiproliferative, reducing kertatinocyte proliferation and induces cell differentiation, normalising epidermal growth.

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11
Q

Calcipotriol contraindications (can’t supply)

A

Calcium disorders

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12
Q

Calcipotriol adverse effects

A

Local skin reactions (sting, itch, rash, peeling, redness)

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13
Q

Calcipotriol advice and self-care

A

Do not apply to face

Protect skin (photosensitivity)

Keep away from dog - can be fatal for them

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14
Q

Chloramphenicol requirements of pharmacist supply

A

For bacterial conjunctivitis in patients older than 2

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15
Q

Chloramphenicol instructions

A

1-2 drops every 2-6 hours for 2-3 days, then reduce frequency. Continue treatment for 48 hours after symptoms subside. Do not wear contact lenses.

Discard 4 weeks after opening

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16
Q

Chloramphenicol mechanism of action

A

Broad spectrum antibiotic

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17
Q

Chloramphenicol contraindications (can’t supply)

A

Contact lens wearer, pregnant or breastfeeding

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18
Q

Chloramphenicol adverse effects

A

Stinging, itching eyes. Usually mild and short-lived.

Hypersensitivity rare

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19
Q

Chloramphenicol advice and self-care

A

Wash hands and do not share face cloths to avoid spread.

To minimize systemic absorption, apply pressure to the tear duct immediately after administration

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20
Q

Chlorpheniramine requirements of pharmacist supply

A

For oral treatment of insomnia from age 6 not containing more than 10 dosage units.

Allergic rhinitis and skin disorders

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21
Q

Chlorpheniramine instructions

A

5mL ut 8 times daily.

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22
Q

Chlorpheniramine mechanism of action

A

First generation antihistamine

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23
Q

Chlorpheniramine contraindications (can’t supply)

A

Under 2 (or 6), acute asthma, pregnancy and breastfeeding

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24
Q

Chlorpheniramine adverse effects

A

Sedation uncommon but still possible

GI: nausea, vomiting, diarrhoea

Antimuscarinic effects

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25
Q

Ciclopirox requirements of pharmacist supply

A

Is POM if it is stronger than 2%, cannot be more than 8%. For external use of fungal infections

Nail laquer (rejuvenail)

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26
Q

Ciclopirox instructions

A

Apply to infected nails every 2 days for 1 month, then twice weekly for the second month and once weekly thereafter for up to 6 months.

Before first application and once weekly remove as much of the affected nail as possible. Once weekly cleanse all lacquer from nail.

If skin irritation persists, discontinue treatment

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27
Q

Ciclopirox mechanism of action

A

Broad spectrum antifungal

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28
Q

Ciclopirox contraindications (can’t supply)

A

Under 18 years of age?? Pregnant/breastfeeding

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29
Q

Ciclopirox adverse effects

A

Skin irritation, nail discolouration, inflammation of the skin

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30
Q

Ciclopirox advice and self-care

A

Good hygiene

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31
Q

Clobetasone requirements of pharmacist supply

A

For dermal use no stronger than 0.005% or more than 30g. Must be in original pack.

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32
Q

Clobetasone instructions

A

Apply sparingly to the affected are 1-2 times daily. Do not use for more than 2 weeks

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33
Q

Clobetasone mechanism of action

A

Moderately potent CC. Act on glucocorticoid receptors to initiate antiinflammatory action

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34
Q

Clobetasone contraindications (can’t supply)

A

Untreated bacterial, viral or fungal infections of the skin. Do not use for acne, rosacea, perioral dermatitis or skin ulcerations.

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35
Q

Clobetasone adverse effects

A

Thinning of skin

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36
Q

Dexchlorpheniramine requirements of pharmacist supply

A

For the treatment of insomnia for patients olfer than 2. Must be in manufacturer’s pack and contain no more than 10 tablets.

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37
Q

Dexchlorpheniramine instructions

A

1 tablet nocte for 7-10 days

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38
Q

Dexchlorpheniramine mechanism of action

A

First generation antihistamine

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39
Q

Dexchlorpheniramine contraindications (can’t supply)

A

Under 2, pregnant or breastfeeding, use of monoamine oxidase inhibitors

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40
Q

Dexchlorpheniramine adverse effects

A

Sedation and anticholinergic effects

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41
Q

Dextromethorphan requirements of pharmacist supply

A

In liquid form: containing no more than 600mg and a recommended daily dose of max 120mg.

For dry cough aged 6 and over.

In tablet form: 25mg max but no more than 30 tablets.

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42
Q

Dextromethorphan instructions

A

10-20mg q4h or 30mg q6-8h. Max 120mg daily.

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43
Q

Dextromethorphan mechanism of action

A

Suppresses cough reflex by acting on the cough centre of the brain (medulla oblongata)

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44
Q

Dextromethorphan contraindications (can’t supply)

A

Monoamine oxidase inhibitor usage (moclobemide)

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45
Q

Dextromethorphan adverse effects

A

GI: nausea, vomiting, constipation

Neuro: confusion, drowsiness, dizziness

General: fatigue, allergic reaction

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46
Q

Diclofenac requirements of pharmacist supply

A

In tablets 12.5-25mg strength. No more than 30 tablets. For pain and inflammation

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47
Q

Diclofenac instructions

A

2 tablets (50mg) as a loading dose, then another 1-2 tablets every 8 hours as necessary. Take with food and a large glass of water.

Max 150mg for adults, 75mg for children older than 14

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48
Q

Diclofenac mechanism of action

A

Reduces prostaglandin production by inhibiting COX 2 resulting in anti-inflammatory and antipyretic effects.

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49
Q

Diclofenac contraindications (can’t supply)

A

Under 14 years

GIMIRI risk/history

Caution in asthmatics

Pregnancy/breastfeeding

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50
Q

Diclofenac adverse effects

A

Heartburn, dyspepsia, nausea, stomach discomfort, diarrhoea.

Report unusual signs of bleeding

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51
Q

Diphenhydramine requirements of pharmacist supply

A

For adults and children over 2 for treatment of insomnia. Must be in original pack and contain no more than 10 units.

52
Q

Diphenhydramine instructions

A

50mg at bedtime if required for 7-10 days

53
Q

Diphenhydramine mechanism of action

A

First generation antihistamine

54
Q

Diphenhydramine contraindications (can’t supply)

A

Glaucoma, prostate problems, difficulty passing urine, stomach blockage/ulcer

Under the age of 12

Pregnant or breastfeeding

55
Q

Diphenhydramine adverse effects

A

Drowsiness, anticholinergic effects,

56
Q

Doxylamine requirements of pharmacist supply

A

For adults and children over 2 for the treatment of insomnia. Must be in original pack and contain no more than 10 units.

57
Q

Doxylamine instructions

A

25mg 30 minutes before bedtime for 7-10 days.

58
Q

Doxylamine mechanism of action

A

First generation antihistamine

59
Q

Doxylamine adverse effects

A

Drowsiness, anticholinergic effects

60
Q

Fluorides requirements of pharmacist supply

A

Tablets: 1.1mg containing no more than 5.

Toothpaste: 1.1%

For prevention of dental caries

61
Q

Fluorides instructions

A

Suck or dissolve tablets

Do not eat or drink for 30 minutes afterwards

Do it at night

62
Q

Fluorides mechanism of action

A

Incorporates fluoride into the tooth enamel, strengthening it and making it more resistant to acid.

63
Q

Fluorides adverse effects

A

Occasionally white flecks on teeth. If dose exceeded yellowish-brown discolouration may occur

64
Q

Glucagon instructions

A

Dissolve the powder in water and inject intramuscularly

65
Q

Glucagon mechanism of action

A

Mobilises/breaks down glycogen stored in liver, increasing the blood glucose levels.

66
Q

Glucagon adverse effects

A

Nausea, vomiting, abdominal pain

67
Q

Glucagon advice and self-care

A

Make sure your friends and family know how to use it if needed. Check the expiry date. Go to doctor after using.

68
Q

Glyceryl Trinitrate requirements of pharmacist supply

A

For oral, sublingual or rectal use.

Haemmorrhoids and angina (Rectogesic)

69
Q

Glyceryl Trinitrate instructions

A

Haemmorrhoids: Insert 1-1.5cm of ointment into the anal canal TDS

Angina: Spray 1-2 doses under the tongue. Can repeat dose after 10 minutes but if still pain does not subside call the ambulance

70
Q

Glyceryl Trinitrate mechanism of action

A

Donates nitric oxide, resulting in relaxation of smooth muscle and vasodilation.

71
Q

Glyceryl Trinitrate contraindications (can’t supply)

A

Severe anemia, glaucoma, hypotension, increased intracranial pressure

Pregnancy/breastfeeding

72
Q

Glyceryl Trinitrate adverse effects

A

Hypotension, headache, facial flush, dizziness

73
Q

Hydrocortisone + Hydrocortisone acetate requirements of pharmacist supply

A

For dermal use up to 1% with no other active ingredient except an antifungal. 30g or less.

74
Q

Hyoscine butylbromide requirements of pharmacist supply

A

For relief of GI muscle spasm. 10mg and no more than 20 dosage units.

Or 20mg and containing no more than 10 units.

75
Q

Hyoscine butylbromide instructions

A

20mg QID. Swallow whole and take with a large glass of water

76
Q

Hyoscine butylbromide mechanism of action

A

Binds to M3 receptors in the GI tract, relaxing smooth muscles. (Antagonist)

77
Q

Hyoscine butylbromide contraindications (can’t supply)

A

Glaucoma

Under 6

78
Q

Hyoscine butylbromide adverse effects

A

Dry mouth, blurred vision, altered mental alertness.

79
Q

Ibuprofen requirements of pharmacist supply

A

Up to 400mg per dose form and containing no more than 50 dose units. Must be in original pack and labelled appropriately

80
Q

Ibuprofen mechanism of action

A

Non-selective COX inhibitor, inhibits prostaglandin synthesis, reducing pain inflammation and fever.

81
Q

Macrogols requirements of pharmacist supply

A

Oral preparations for bowel cleansing prior to diagnostic, medical or surgical procedures

82
Q

Macrogols instructions

A

Dissolve the sachet in water either the evening before the procedure or early in the morning on the day. Treatment should be finished at least 1 hour before colonoscopy.

83
Q

Macrogols mechanism of action

A

Osmotic laxative that increases the water content of stool, softening it and promoting bowel movement

84
Q

Macrogols contraindications (can’t supply)

A

GI obstruction

85
Q

Macrogols adverse effects

A

Flatulence, abdominal pain, nausea and colic

86
Q

Macrogols advice and self-care

A

Do not have any food for at least 2 hours prior

Ensure adequate hydration

Take any oral medication at least 1 hour before treatment

Onset is 1 hour and should be complete within 4 hours

87
Q

Paracetamol requirements of pharmacist supply

A

Modified release containing no more than 665mg and 96 tablets.

For OA and muscle aches and pains.

88
Q

Paracetamol instructions

A

2 tablets TDS every 6-8 hours as needed. No more than 6 tablets in 24 hours.

Swallow whole with liquid

89
Q

Paracetamol mechanism of action

A

Inhibits prostaglandin synthesis, reducing pain and fever.

90
Q

Paracetamol contraindications (can’t supply)

A

Under 12

91
Q

Pholcodine requirements of pharmacist supply

A

For dry cough

Not more than 15mg in solid dosage form, maximum daily dose not exceeding 100mg.

92
Q

Pholcodine instructions

A

10mg up to 6 times daily BUT Duro Tuss says 10-15mg QID max.

93
Q

Pholcodine mechanism of action

A

Suppresses cough reflex by acting on the cough centre in the brain (medulla oblongata)

94
Q

Pholcodine contraindications (can’t supply)

A

Under 6

Monoamine oxidase inhibitors

Pregnant/breastfeeding

95
Q

Pholcodine adverse effects

A

Nausea, vomiting, constipation, drowsiness

96
Q

Promethazine requirements of pharmacist supply

A

For oral use in adults and children over 2 for the treatment of insomnia.

Must be in original pack and contain no more than 10 units

97
Q

Promethazine instructions

A

25-75 mg OD nocte.

98
Q

Promethazine mechanism of action

A

First generation antihistamine

99
Q

Promethazine adverse effects

A

Drowsiness, sedation, dry mouth

100
Q

Salicylic acid requirements of pharmacist supply

A

For dermal use containing 40% or less.

Used in acne, corns and calluses

101
Q

Salicylic acid mechanism of action

A

Antikeratolytic (softens keratin). This helps loosen dry scaly skin making it easier to remove.

102
Q

Salicylic acid adverse effects

A

Moderate to severe skin irritation, flushing, unusually warm/reddening skin.

103
Q

Salicylic acid advice and self-care

A

Do not apply to broken skin or mucous membranes

Wash hands afterward

104
Q

Sodium phosphate requirements of pharmacist supply

A

For bowel cleansing prior to diagnostic, medical or surgical procedures.

Oral preparations

105
Q

Sodium phosphate instructions

A

First dose over 1 hour, then repeat after 10-12 hours

106
Q

Sodium phosphate mechanism of action

A

Osmotic laxative, drawing water to the stool and promoting bowel movement

107
Q

Sodium phosphate contraindications (can’t supply)

A

GI obstruction, under 12

108
Q

Sodium phosphate adverse effects

A

Nausea, vomiting, abdominal pain

109
Q

Sodium phosphate advice and self-care

A

Lots of hydration, take first dose 24 hours procedure.

Should take 30-60 minutes

110
Q

Sodium picosulfate requirements of pharmacist supply

A

In oral preparations for bowel cleansing prior to medical, diagnostic or surgical procedures

111
Q

Sodium picosulfate mechanism of action

A

Is a stimulant laxative. Increases motility and promotes bowel movement

112
Q

Sodium picosulfate adverse effects

A

Abdominal cramps, nausea, vomiting, diarrhoea

113
Q

Staph aureus + Strep B haem vaccine (BUCCALINE) requirements of pharmacist supply

A

In oral vaccines for the prophylaxis of bacterial complications of colds

114
Q

Staph aureus + Strep B haem vaccine (BUCCALINE) instructions

A

Children under 7: 1 tab for 2 days, then 2 tabs on the third day

Over 7: 1 tab first day, 2 tabs second, four.

115
Q

Staph aureus + Strep B haem vaccine (BUCCALINE) mechanism of action

A

Inactivated cell vaccine

116
Q

Staph aureus + Strep B haem vaccine (BUCCALINE) adverse effects

A

Nausea, abdominal pain, vomiting, diarrhoea

117
Q

Staph aureus + Strep B haem vaccine (BUCCALINE) advice and self-care

A

Does not make up for flu vaccine

118
Q

Theophylline requirements of pharmacist supply

A

When in liquid form containing 2% or less

119
Q

Theophylline instructions

A

25mL q6h.

120
Q

Theophylline mechanism of action

A

Xanthine derivative

Inhibits phophodiesterase type 3 and 4, realxing smooth muscles and causing bronchodilation

121
Q

Theophylline contraindications (can’t supply)

A

Under 2

122
Q

Theophylline adverse effects

A

Nausea, vomiting, GI irritation, diarrhoea

123
Q

Theophylline advice and self-care

A

Smoking (cigarettes or weed) and caffeine may change the effect of theophylline

124
Q

Trimeprazin requirements of pharmacist supply

A

For oral use in adults and children over 2 for the treatment of insomnia.

Must be in original pack and contain no more than 10 units

125
Q

Trimeprazin + tripolidine mechanism of action

A

First generation antihistamine